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Details

Stereochemistry ACHIRAL
Molecular Formula C32H24N6O6S2
Molecular Weight 652.7
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 2
Charge 0

SHOW SMILES / InChI
Structure of CONGO RED FREE ACID

SMILES

NC1=C(C=C(C2=CC=CC=C12)S(O)(=O)=O)\N=N\C3=CC=C(C=C3)C4=CC=C(C=C4)\N=N\C5=CC(=C6C=CC=CC6=C5N)S(O)(=O)=O

InChI

InChIKey=HFHIDKQMGIGARX-ATXIYDNESA-N
InChI=1S/C32H24N6O6S2/c33-31-25-7-3-1-5-23(25)29(45(39,40)41)17-27(31)37-35-21-13-9-19(10-14-21)20-11-15-22(16-12-20)36-38-28-18-30(46(42,43)44)24-6-2-4-8-26(24)32(28)34/h1-18H,33-34H2,(H,39,40,41)(H,42,43,44)/b37-35+,38-36+

HIDE SMILES / InChI

Molecular Formula C32H24N6O6S2
Molecular Weight 652.7
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 2
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Filipin prevents pathological prion protein accumulation by reducing endocytosis and inducing cellular PrP release.
2002 Jul 12
Imaging beta-amyloid plaques and neurofibrillary tangles in the aging human brain.
2004
Harnessing chaperones to generate small-molecule inhibitors of amyloid beta aggregation.
2004 Oct 29
Quantification of cerebral amyloid angiopathy and parenchymal amyloid plaques with Congo red histochemical stain.
2006
Flavonoids possess neuroprotective effects on cultured pheochromocytoma PC12 cells: a comparison of different flavonoids in activating estrogenic effect and in preventing beta-amyloid-induced cell death.
2007 Mar 21
Patents
Substance Class Chemical
Created
by admin
on Sat Dec 16 08:26:45 GMT 2023
Edited
by admin
on Sat Dec 16 08:26:45 GMT 2023
Record UNII
8KB6BS2FOH
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
CONGO RED FREE ACID
Common Name English
1-NAPHTHALENESULFONIC ACID, 3,3'-((1,1'-BIPHENYL)-4,4'-DIYLBIS(AZO))BIS(4-AMINO-
Systematic Name English
3,3'-((1,1'-BIPHENYL)-4,4'-DIYLBIS(2,1-DIAZENEDIYL))BIS(4-AMINO-1-NAPHTHALENESULFONIC ACID)
Systematic Name English
C.I. DIRECT RED 28 FREE ACID
Common Name English
1-NAPHTHALENESULFONIC ACID, 3,3'-((1,1'-BIPHENYL)-4,4'-DIYLBIS(2,1-DIAZENEDIYL))BIS(4-AMINO-
Systematic Name English
Code System Code Type Description
RXCUI
2391143
Created by admin on Sat Dec 16 08:26:45 GMT 2023 , Edited by admin on Sat Dec 16 08:26:45 GMT 2023
PRIMARY
CAS
14684-01-6
Created by admin on Sat Dec 16 08:26:45 GMT 2023 , Edited by admin on Sat Dec 16 08:26:45 GMT 2023
PRIMARY
PUBCHEM
11314
Created by admin on Sat Dec 16 08:26:45 GMT 2023 , Edited by admin on Sat Dec 16 08:26:45 GMT 2023
PRIMARY
EPA CompTox
DTXSID0048428
Created by admin on Sat Dec 16 08:26:45 GMT 2023 , Edited by admin on Sat Dec 16 08:26:45 GMT 2023
PRIMARY
FDA UNII
8KB6BS2FOH
Created by admin on Sat Dec 16 08:26:45 GMT 2023 , Edited by admin on Sat Dec 16 08:26:45 GMT 2023
PRIMARY
Related Record Type Details
SALT/SOLVATE -> PARENT
TARGET -> INHIBITOR
Related Record Type Details
ACTIVE MOIETY