Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C10H13NO4 |
| Molecular Weight | 211.2145 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
C[C@@](N)(CC1=CC=C(O)C(O)=C1)C(O)=O
InChI
InChIKey=CJCSPKMFHVPWAR-SNVBAGLBSA-N
InChI=1S/C10H13NO4/c1-10(11,9(14)15)5-6-2-3-7(12)8(13)4-6/h2-4,12-13H,5,11H2,1H3,(H,14,15)/t10-/m1/s1
| Molecular Formula | C10H13NO4 |
| Molecular Weight | 211.2145 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
D-Methyldopa is an inactive isomer of methyldopa. It is known, that only L-isomer has the ability to inhibit dopa decarboxylase and possesses the antihypertensive activity in man. Moreover, about twice the dose of the racemate (DL-form of methyldopa) is required for the equal antihypertensive effect.
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 08:04:59 GMT 2023
by
admin
on
Sat Dec 16 08:04:59 GMT 2023
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| Record UNII |
8K91SZC8W9
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| Record Status |
Validated (UNII)
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| Record Version |
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NCT00976235
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DTXSID50859484
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8K91SZC8W9
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2799-15-7
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admin on Sat Dec 16 08:04:59 GMT 2023 , Edited by admin on Sat Dec 16 08:04:59 GMT 2023
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721860
Created by
admin on Sat Dec 16 08:04:59 GMT 2023 , Edited by admin on Sat Dec 16 08:04:59 GMT 2023
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| Related Record | Type | Details | ||
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PARENT -> IMPURITY |
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
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ACTIVE MOIETY |
IMT-002 (D-MDOPA) is an oral small molecule drug being developed to treat T1D in patients with the HLA-DQ8 gene. When HLA-DQ8 function is inhibited, the immune system will no longer attack insulin producing beta-cells,
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