FENETHAZINE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C16H18N2S
Molecular Weight	270.393
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of FENETHAZINE

Structure Search

SMILES

CN(C)CCN1C2=C(SC3=C1C=CC=C3)C=CC=C2

InChI

InChIKey=PFAXACNYGZVKMX-UHFFFAOYSA-N

InChI=1S/C16H18N2S/c1-17(2)11-12-18-13-7-3-5-9-15(13)19-16-10-6-4-8-14(16)18/h3-10H,11-12H2,1-2H3

HIDE SMILES / InChI

Molecular Formula	C16H18N2S
Molecular Weight	270.393
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/12677184 | https://www.drugfuture.com/chemdata/fenethazine.html | http://www.hmdb.ca/metabolites/HMDB0240228

FENETHAZINE was a first-generation phenothiazine-derived antihistamine drug. Promethazine was derived from FENETHAZINE.

Originator

Approval Year

PubMed

PubMed

Title	Date	PubMed
The 50th Anniversary of Chlorpromazine.	2002-09	12677184

Substance Class	Chemical Created by `admin` on `Wed Apr 02 09:33:26 GMT 2025` Edited by `admin` on `Wed Apr 02 09:33:26 GMT 2025`
Record UNII	8J97CUZ4HX
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

FENETHAZINE [MI]

Preferred Name

English

FENETHAZINE

Official Name

English

Fenethazine [WHO-DD]

Common Name

English

10-(2-DIMETHYLAMINOETHYL)PHENOTHIAZINE

Systematic Name

English

fenethazine [INN]

Common Name

English

PHENETHAZINE

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29578

Created by admin on Wed Apr 02 09:33:26 GMT 2025 , Edited by admin on Wed Apr 02 09:33:26 GMT 2025

Code System Code Type Description

DRUG CENTRAL

3747

Created by admin on Wed Apr 02 09:33:26 GMT 2025 , Edited by admin on Wed Apr 02 09:33:26 GMT 2025

PRIMARY

MESH

C014551

Created by admin on Wed Apr 02 09:33:26 GMT 2025 , Edited by admin on Wed Apr 02 09:33:26 GMT 2025

PRIMARY

NCI_THESAURUS

C65646

Created by admin on Wed Apr 02 09:33:26 GMT 2025 , Edited by admin on Wed Apr 02 09:33:26 GMT 2025

PRIMARY

ECHA (EC/EINECS)

208-325-1

Created by admin on Wed Apr 02 09:33:26 GMT 2025 , Edited by admin on Wed Apr 02 09:33:26 GMT 2025

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EPA CompTox

DTXSID30200233

Created by admin on Wed Apr 02 09:33:26 GMT 2025 , Edited by admin on Wed Apr 02 09:33:26 GMT 2025

PRIMARY

ChEMBL

CHEMBL2106299

Created by admin on Wed Apr 02 09:33:26 GMT 2025 , Edited by admin on Wed Apr 02 09:33:26 GMT 2025

PRIMARY

EVMPD

SUB07558MIG

Created by admin on Wed Apr 02 09:33:26 GMT 2025 , Edited by admin on Wed Apr 02 09:33:26 GMT 2025

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INN

1860

Created by admin on Wed Apr 02 09:33:26 GMT 2025 , Edited by admin on Wed Apr 02 09:33:26 GMT 2025

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CAS

522-24-7

Created by admin on Wed Apr 02 09:33:26 GMT 2025 , Edited by admin on Wed Apr 02 09:33:26 GMT 2025

PRIMARY

FDA UNII

8J97CUZ4HX

Created by admin on Wed Apr 02 09:33:26 GMT 2025 , Edited by admin on Wed Apr 02 09:33:26 GMT 2025

PRIMARY

PUBCHEM

68223

Created by admin on Wed Apr 02 09:33:26 GMT 2025 , Edited by admin on Wed Apr 02 09:33:26 GMT 2025

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WIKIPEDIA

Fenethazine

Created by admin on Wed Apr 02 09:33:26 GMT 2025 , Edited by admin on Wed Apr 02 09:33:26 GMT 2025

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MERCK INDEX

m186

Created by admin on Wed Apr 02 09:33:26 GMT 2025 , Edited by admin on Wed Apr 02 09:33:26 GMT 2025

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Merck Index

SMS_ID

100000081252

Created by admin on Wed Apr 02 09:33:26 GMT 2025 , Edited by admin on Wed Apr 02 09:33:26 GMT 2025

PRIMARY

Related Record Type Details


					225AVG0161

FENETHAZINE HYDROCHLORIDE

SALT/SOLVATE -> PARENT

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					8J97CUZ4HX

ACTIVE MOIETY