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Details

Stereochemistry ACHIRAL
Molecular Formula C2H3O3.H4N
Molecular Weight 93.0819
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of AMMONIUM GLYCOLATE

SMILES

[NH4+].OCC([O-])=O

InChI

InChIKey=UBKBVPONTPMQQW-UHFFFAOYSA-N
InChI=1S/C2H4O3.H3N/c3-1-2(4)5;/h3H,1H2,(H,4,5);1H3

HIDE SMILES / InChI

Molecular Formula H3N
Molecular Weight 17.0305
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C2H4O3
Molecular Weight 76.0514
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

SODIUM GLYCOLATE, a sodium salt of carboxymethyl ether, is used as a pharmaceutical grade dissolution excipient for solid dosage forms. It absorbs water rapidly, resulting in swelling which leads to the rapid disintegration of tablets and capsules. Without a disintegrant, these may not dissolve appropriately and may effect the amount of active ingredient absorbed, thereby decreasing effectiveness.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Preventing
CLEAR CELL SALICYLIC CLARIFYING TONIC

Approved Use

Prevention and treatment of Acne and acne-prone skin. A salicylic/glycolic acid skin clarifying removes excess surface oil. A blend of anti-oxidants leaves skin fresh and shine-free.

Launch Date

2009
PubMed

PubMed

TitleDatePubMed
The integration of paclitaxel and new platinum compounds in the treatment of advanced ovarian cancer.
2001
Iron coordination in photosystem II: interaction between bicarbonate and the QB pocket studied by Fourier transform infrared spectroscopy.
2001 Apr 3
[Tissue platinum distribution and the effect following intra-arterial injection of cisplatin to metastatic liver cancer--a case report].
2001 Aug
[Evaluation of a combination chemotherapy with nedaplatin and 5-FU for oral cancers].
2001 Aug
Ethylene glycol-mediated tubular injury: identification of critical metabolites and injury pathways.
2001 Aug
Structure of an active soluble mutant of the membrane-associated (S)-mandelate dehydrogenase.
2001 Aug 21
Perturbation of rat renal tubule transport of the organic cation amantadine in recent onset streptozotocin-induced diabetes and in uninephrectomy.
2001 Jan
Local structure analysis of Ti species stabilized in ion exchangeable layer solids by x-ray absorption spectroscopy.
2001 Mar 1
Biochemical characterization of the 2-ketoacid reductases encoded by ycdW and yiaE genes in Escherichia coli.
2001 Mar 15
[Effect of combination chemotherapy with nedaplatin and 5-FU for head and neck squamous cell carcinoma].
2001 Sep
A dynamic study and modeling of the formation of polyhydroxyalkanoates combined with treatment of high strength wastewater.
2001 Sep 1
Fast- and slow-release tablets for oral administration of flavonoids: rutin and quercetin.
2002 Apr
Identification of a set of genes involved in the formation of the substrate for the incorporation of the unusual "glycolate" chain extension unit in ansamitocin biosynthesis.
2002 Apr 24
Phase I study of combination chemotherapy with 5-fluorouracil (5-FU) and nedaplatin (NDP): adverse effects and eecommended dose of NDP administered after 5-FU.
2002 Dec
Insights into substrate binding and catalytic mechanism of human tyrosyl-DNA phosphodiesterase (Tdp1) from vanadate and tungstate-inhibited structures.
2002 Dec 13
Drought and oxidative load in the leaves of C3 plants: a predominant role for photorespiration?
2002 Jun
Purification and characterization of malate synthase from the glucose-grown wood-rotting basidiomycete Fomitopsis palustris.
2002 Mar
An inherited metabolic disorder presenting as ethylene glycol intoxication in a young adult.
2002 Mar
[Chemoradiation therapy for esophageal cancer].
2002 May
Sensitive and real-time determination of H2O2 release from intact peroxisomes.
2002 May 1
[Clinical study of the combination of small amount of nedaplatin (CDGP)/5-FU with radiation for the treatment of esophageal cancer].
2002 Oct
Total synthesis of (+)-geldanamycin and (-)-o-quinogeldanamycin with use of asymmetric anti- and syn-glycolate aldol reactions.
2002 Oct 3
Evaluation of the effect of triterpenes on urinary risk factors of stone formation in pyridoxine deficient hyperoxaluric rats.
2002 Sep
Patents
Substance Class Chemical
Created
by admin
on Fri Dec 15 20:17:32 GMT 2023
Edited
by admin
on Fri Dec 15 20:17:32 GMT 2023
Record UNII
8G1X5P7GIL
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
AMMONIUM GLYCOLATE
INCI  
INCI  
Official Name English
ACETIC ACID, 2-HYDROXY-, AMMONIUM SALT (1:1)
Common Name English
ACETIC ACID, HYDROXY-, MONOAMMONIUM SALT
Common Name English
AMMONIUM HYDROXYACETATE
Systematic Name English
AMMONIUM GLYCOLATE [INCI]
Common Name English
HYDROXYACETIC ACID AMMONIUM SALT
Common Name English
GLICONOL L
Common Name English
Code System Code Type Description
FDA UNII
8G1X5P7GIL
Created by admin on Fri Dec 15 20:17:32 GMT 2023 , Edited by admin on Fri Dec 15 20:17:32 GMT 2023
PRIMARY
CAS
35249-89-9
Created by admin on Fri Dec 15 20:17:32 GMT 2023 , Edited by admin on Fri Dec 15 20:17:32 GMT 2023
PRIMARY
PUBCHEM
169677
Created by admin on Fri Dec 15 20:17:32 GMT 2023 , Edited by admin on Fri Dec 15 20:17:32 GMT 2023
PRIMARY
EPA CompTox
DTXSID6049642
Created by admin on Fri Dec 15 20:17:32 GMT 2023 , Edited by admin on Fri Dec 15 20:17:32 GMT 2023
PRIMARY
Related Record Type Details
PARENT -> SALT/SOLVATE
Related Record Type Details
ACTIVE MOIETY