Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C2H3O3.H4N |
| Molecular Weight | 93.0819 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[NH4+].OCC([O-])=O
InChI
InChIKey=UBKBVPONTPMQQW-UHFFFAOYSA-N
InChI=1S/C2H4O3.H3N/c3-1-2(4)5;/h3H,1H2,(H,4,5);1H3
| Molecular Formula | C2H4O3 |
| Molecular Weight | 76.0514 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | H3N |
| Molecular Weight | 17.0305 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
SODIUM GLYCOLATE, a sodium salt of carboxymethyl ether, is used as a pharmaceutical grade dissolution excipient for solid dosage forms. It absorbs water rapidly, resulting in swelling which leads to the rapid disintegration of tablets and capsules. Without a disintegrant, these may not dissolve appropriately and may effect the amount of active ingredient absorbed, thereby decreasing effectiveness.
Approval Year
Conditions
| Condition | Modality | Targets | Highest Phase | Product |
|---|---|---|---|---|
| Preventing | CLEAR CELL SALICYLIC CLARIFYING TONIC Approved UsePrevention and treatment of Acne and acne-prone skin. A salicylic/glycolic acid skin clarifying removes excess surface oil. A blend of anti-oxidants leaves skin fresh and shine-free. Launch Date1.26230397E12 |
PubMed
| Title | Date | PubMed |
|---|---|---|
| Simultaneous determination of ethylene glycol and glycolic acid in serum by gas chromatography-mass spectrometry. | 1999 Nov-Dec |
|
| Evaluation of the functional equivalence of crospovidone NF from different sources. I. Physical characterization. | 2001 |
|
| Cytocidal effect and DNA damage of nedaplatin in vitro by simulating pharmacokinetic parameters. | 2001 Apr |
|
| The gene yghK linked to the glc operon of Escherichia coli encodes a permease for glycolate that is structurally and functionally similar to L-lactate permease. | 2001 Apr |
|
| Combinatory anti-tumor effects of electroporation-mediated chemotherapy and wild-type p53 gene transfer to human esophageal cancer cells. | 2001 Apr |
|
| Iron coordination in photosystem II: interaction between bicarbonate and the QB pocket studied by Fourier transform infrared spectroscopy. | 2001 Apr 3 |
|
| Activity staining of isocitrate lyase after electrophoresis on either native or sodium dodecyl sulfate polyacrylamide gels. | 2001 Aug |
|
| An easy screening method for fungi producing ochratoxin A in pure culture. | 2001 Dec 30 |
|
| Bioadhesive properties of hydroxypropylcellulose topical films produced by hot-melt extrusion. | 2001 Feb 23 |
|
| Perturbation of rat renal tubule transport of the organic cation amantadine in recent onset streptozotocin-induced diabetes and in uninephrectomy. | 2001 Jan |
|
| Preclinical in vivo antitumor efficacy of nedaplatin with gemcitabine against human lung cancer. | 2001 Jan |
|
| Phenotypic expression of primary hyperoxaluria: comparative features of types I and II. | 2001 Jan |
|
| Phase I/II study of intravenous nedaplatin and intraarterial cisplatin with transcatheter arterial embolization for patients with locally advanced uterine cervical carcinoma. | 2001 Jan 1 |
|
| [A case of esophageal carcinoma with multiple liver metastases successfully treated with nedaplatin (NDP) and 5-fluorouracil (5-FU) combined with radiotherapy]. | 2001 Jun |
|
| Biodegradable microspheres of novel segmented poly(ether-ester-amide)s based on poly(epsilon-caprolactone) for the delivery of bioactive compounds. | 2001 Jun |
|
| [Concurrent chemoradiotherapy for advanced cervical cancer--a pilot study]. | 2001 Mar |
|
| Biochemical characterization of the 2-ketoacid reductases encoded by ycdW and yiaE genes in Escherichia coli. | 2001 Mar 15 |
|
| Pharmacokinetics and pharmacodynamics of serum platinum of gynecologic cancer patients treated with nedaplatin. | 2001 Nov-Dec |
|
| [Small cell carcinoma of the urinary bladder: a case report]. | 2001 Oct |
|
| AGXT gene mutations and their influence on clinical heterogeneity of type 1 primary hyperoxaluria. | 2001 Oct |
|
| Multiple sources of sodium starch glycolate, NF: evaluation of functional equivalence and development of standard performance tests. | 2002 |
|
| Global expression profiling of acetate-grown Escherichia coli. | 2002 Apr 12 |
|
| Identification of a set of genes involved in the formation of the substrate for the incorporation of the unusual "glycolate" chain extension unit in ansamitocin biosynthesis. | 2002 Apr 24 |
|
| Potential mechanisms of marked hyperoxaluria not due to primary hyperoxaluria I or II. | 2002 Aug |
|
| Phase I study of combination chemotherapy with 5-fluorouracil (5-FU) and nedaplatin (NDP): adverse effects and eecommended dose of NDP administered after 5-FU. | 2002 Dec |
|
| Insights into substrate binding and catalytic mechanism of human tyrosyl-DNA phosphodiesterase (Tdp1) from vanadate and tungstate-inhibited structures. | 2002 Dec 13 |
|
| Primary hyperoxaluria: a rare but important cause of nephrolithiasis. | 2002 Jun |
|
| An inherited metabolic disorder presenting as ethylene glycol intoxication in a young adult. | 2002 Mar |
|
| [Chemoradiation therapy for esophageal cancer]. | 2002 May |
|
| [Combination chemotherapy of paclitaxel followed by nedaplatin for human ovarian cancer]. | 2002 Nov |
|
| Metabolic shifts in hypersaline microbial mats upon addition of organic substrates. | 2002 Nov |
|
| Genetic analysis--a diagnostic tool for primary hyperoxaluria type I. | 2002 Nov |
|
| The combined effect of drought stress and heat shock on gene expression in tobacco. | 2002 Nov |
|
| Irinotecan plus cisplatin has substantial antitumor effect as salvage chemotherapy against germ cell tumors. | 2002 Nov 1 |
|
| Carbon exchange in hot alkaline degradation of glucose. | 2002 Nov 29 |
|
| [Clinical study of the combination of small amount of nedaplatin (CDGP)/5-FU with radiation for the treatment of esophageal cancer]. | 2002 Oct |
|
| Platinum drugs in the treatment of non-small-cell lung cancer. | 2002 Oct 7 |
|
| Powder compaction properties of sodium starch glycolate disintegrants. | 2002 Sep |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Thu Jul 06 03:16:23 UTC 2023
by
admin
on
Thu Jul 06 03:16:23 UTC 2023
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| Record UNII |
8G1X5P7GIL
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| Record Status |
Validated (UNII)
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35249-89-9
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169677
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DTXSID6049642
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admin on Thu Jul 06 03:16:23 UTC 2023 , Edited by admin on Thu Jul 06 03:16:23 UTC 2023
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| Related Record | Type | Details | ||
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PARENT -> SALT/SOLVATE |
| Related Record | Type | Details | ||
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ACTIVE MOIETY |