CLOPERIDONE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C21H23ClN4O2
Molecular Weight	398.886
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

ClC1=CC=CC(=C1)N2CCN(CCCN3C(=O)NC4=C(C=CC=C4)C3=O)CC2

InChI

InChIKey=FXZJKVODWNYPKK-UHFFFAOYSA-N

InChI=1S/C21H23ClN4O2/c22-16-5-3-6-17(15-16)25-13-11-24(12-14-25)9-4-10-26-20(27)18-7-1-2-8-19(18)23-21(26)28/h1-3,5-8,15H,4,9-14H2,(H,23,28)

HIDE SMILES / InChI

Molecular Formula	C21H23ClN4O2
Molecular Weight	398.886
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/5885076

Cloperidone is a quinazolinedione derivative with sedative and antihypertensive properties. Cloperidone was discovered in 1965 by Miles Laboratories. The activity of the compound was demonstrated by behavioral observations in dogs and cats, by rotarod and activity cage experiments in mice and in other models.

Approval Year

PubMed

Title	Date	PubMed
New sedative and hypotensive 3-substituted 2,4(1H,3H)-quinazolinediones.	1965 Nov	5885076

Substance Class	Chemical Created by `admin` on `Fri Dec 15 17:13:38 GMT 2023` Edited by `admin` on `Fri Dec 15 17:13:38 GMT 2023`
Record UNII	8FP5Y6U39R
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

CLOPERIDONE

Official Name

English

Cloperidone [WHO-DD]

Common Name

English

3-(3-(4-(M-CHLOROPHENYL)-1-PIPERAZINYL)PROPYL)-2,4-(1H,3H)-QUINAZOLINEDIONE

Systematic Name

English

2,4(1H,3H)-QUINAZOLINEDIONE, 3-(3-(4-(3-CHLOROPHENYL)-1-PIPERAZINYL)PROPYL)-

Systematic Name

English

cloperidone [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29756