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Details

Stereochemistry ABSOLUTE
Molecular Formula C4H5O6.H4N
Molecular Weight 167.1174
Optical Activity UNSPECIFIED
Defined Stereocenters 2 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of AMMONIUM BITARTRATE

SMILES

[NH4+].O[C@H]([C@@H](O)C([O-])=O)C(O)=O

InChI

InChIKey=ZMFVLYPTTFPBNG-ZVGUSBNCSA-N
InChI=1S/C4H6O6.H3N/c5-1(3(7)8)2(6)4(9)10;/h1-2,5-6H,(H,7,8)(H,9,10);1H3/t1-,2-;/m1./s1

HIDE SMILES / InChI

Molecular Formula H3N
Molecular Weight 17.0305
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C4H6O6
Molecular Weight 150.0868
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 2 / 2
E/Z Centers 0
Optical Activity UNSPECIFIED

Tartaric acid is found in many plants such as grapes, tamarinds, pineapples, mulberries and so on. Wine lees (called mud in the US), the sediment collected during the fermentation of grapes, contains potassium bitartrate (potassium hydrogen tartrate) as its major component. L-(+)-tartaric acid is an enantiomer of tartaric acid. Twenty five years before the tetrahedral structure for carbon was proposed in 1874 to explain the optical activity and other properties of organic compounds, Louis Pasteur discovered the existence of enantiomerism in tartaric acid. L-(+)-tartaric acid is widely used in food and beverage as acidity regulator with E number E334.

Originator

Curator's Comment: Scheele first prepared tartaric acid. Louis Pasteur discovered the existence of enantiomerism in tartaric acid

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Inactive ingredient
CLEARASIL DAILY CLEAR CLEAR SKIN

Approved Use

Unknown
Sourcing

Sourcing

Vendor/AggregatorIDURL
PubMed

PubMed

TitleDatePubMed
Inhibition of leukotriene function can modulate particulate-induced changes in bone cell differentiation and activity.
2001
Studies on the association of 2-thiazolidinecarboxylic acid and antimony potassium tartrate: chiral recognition and prediction of absolute configuration by electrospray ionization mass spectrometry.
2001
L-prolinium tartrate.
2001 Apr
Effect of brimonidine tartrate ophthalmic solution 0.2% on pupil size in normal eyes under different luminance conditions.
2001 Apr
A novel and simplified route to the synthesis of N3S chelators for 99mTc labeling.
2001 Aug
Synthesis and evaluation of a C-glycosyl nucleoside as an inhibitor of chitin synthase.
2001 Aug 30
Production and chemiluminescent free radical reactions of glyoxal in lipid peroxidation of linoleic acid by the ligninolytic enzyme, manganese peroxidase.
2001 Dec
A comparison of salts for the crystallization of macromolecules.
2001 Feb
Reversal of multidrug resistance-associated protein-mediated drug resistance in cultured human neuroblastoma cells by the quinolone antibiotic difloxacin.
2001 Jan
Cell-surface recognition of biotinylated membrane proteins requires very long spacer arms: an example from glucose-transporter probes.
2001 Jan 8
Comparison of the clinical success and quality-of-life impact of brimonidine 0.2% and betaxolol 0.25 % suspension in patients with elevated intraocular pressure.
2001 Jul
Arsenic induces expression of the multidrug resistance-associated protein 2 (MRP2) gene in primary rat and human hepatocytes.
2001 Jul
A Mg-dependent ecto-ATPase in Leishmania amazonensis and its possible role in adenosine acquisition and virulence.
2001 Jul 1
Isolation and characterization of Mn(III) tartrate from Phanerochaete chrysosporium culture broth.
2001 Jul 24
Determination of organic acids of low molecular weight and phosphate in soil by capillary electrophoresis.
2001 Jul-Aug
Dicaffeoyl- or digalloyl pyrrolidine and furan derivatives as HIV integrase inhibitors.
2001 Jun
Chiral separations of transition metal complexes using capillary zone electrophoresis.
2001 Jun 15
Classification of Ralstonia pickettii biovar 3/'thomasii' strains (Pickett 1994) and of new isolates related to nosocomial recurrent meningitis as Ralstonia mannitolytica sp. nov.
2001 Mar
Crystal structure analysis and chiral recognition study of Delta-[Ru(bpy)2(py)2][(+)-O,O'-dibenzoylD-tartrate].12H2O and Lambda-[Ru(bpy)2(py)2][(-)-O,O'-dibenzoyl-L-tartrate].12H2O.
2001 Mar 12
Chemical and biochemical issues related to X-ray crystallography of the ligand-binding domain of estrogen receptor alpha.
2001 May-Jun
Synthesis, characterization, and labeling with 99mTc/188Re of peptide conjugates containing a dithia-bisphosphine chelating agent.
2001 May-Jun
Technetium-99m direct radiolabeling of lanreotide: a somatostatin analog.
2001 Nov
Direct chiral resolution of malic acid in apple juice by ligand-exchange capillary electrophoresis using copper(II)-L-tartaric acid as a chiral selector.
2001 Sep
Oxidation of hydroquinones by the versatile ligninolytic peroxidase from Pleurotus eryngii. H2O2 generation and the influence of Mn2+.
2001 Sep
Sodium stibogluconate is a potent inhibitor of protein tyrosine phosphatases and augments cytokine responses in hemopoietic cell lines.
2001 Sep 15
Novel bicistronic retroviral vector expressing gamma-glutamylcysteine synthetase and the multidrug resistance protein 1 (MRP1) protects cells from MRP1-effluxed drugs and alkylating agents.
2001 Sep 20
The MRP1-mediated effluxes of arsenic and antimony do not require arsenic-glutathione and antimony-glutathione complex formation.
2002 Apr
Acid phosphatases.
2002 Apr
Initial stages of cell-matrix adhesion can be mediated and modulated by cell-surface hyaluronan.
2002 Apr
Stereoselective synthesis of myo-inositol via ring-closing metathesis: a building block for glycosylphosphatidylinositol (GPI) anchor synthesis.
2002 Apr 18
Thermophysical properties of pharmaceutically compatible buffers at sub-zero temperatures: implications for freeze-drying.
2002 Feb
Retention of anions on silica-based metalloporphyrin stationary phases.
2002 Feb
Ergotamine-induced anorectal strictures: report of five cases.
2002 Feb
Diaquabis[mu-(R,R)-tartrato-kappa4O1,O2:O3,O4]dinickel(II) trihydrate.
2002 Feb
Screening method for inherited disorders of purine and pyrimidine metabolism by capillary electrophoresis with reversed electroosmotic flow.
2002 Feb 15
Some comparative aspects of the pharmacokinetics of tylosin in buffaloes and cattle.
2002 Jan
Anaerobaculum mobile sp. nov., a novel anaerobic, moderately thermophilic, peptide-fermenting bacterium that uses crotonate as an electron acceptor, and emended description of the genus Anaerobaculum.
2002 Jan
In vitro antibiotic susceptibility of field isolates of Mycoplasma synoviae in Argentina.
2002 Jan-Mar
A simple spectrophotometric method for the determination of copper in industrial, environmental, biological and soil samples using 2,5-dimercapto-1,3,4-thiadiazole.
2002 Jul
Boronic acid receptors for alpha-hydroxycarboxylates: high affinity of Shinkai's glucose receptor for tartrate.
2002 Jul 26
Improving the labeling of S-acetyl NHS-MAG(3)-conjugated morpholino oligomers.
2002 Jul-Aug
Stereoselective radical reactions of some tartaric and glyceric acid derivatives.
2002 Jun 13
The separation of racemic crystals into enantiomers by chiral block copolymers.
2002 Jun 3
Recruitment, augmentation and apoptosis of rat osteoclasts in 1,25-(OH)2D3 response to short-term treatment with 1,25-dihydroxyvitamin D3 in vivo.
2002 Jun 7
Role of the Multidrug Resistance Protein 1 in protection from heavy metal oxyanions: investigations in vitro and in MRP1-deficient mice.
2002 Mar 1
Consumption of an omega-3 fatty acids product, INCELL AAFA, reduced side-effects of CPT-11 (irinotecan) in mice.
2002 Mar 18
Use of disposable GRC electrodes for the detection of phenol and chlorophenols in liquid chromatography.
2002 May
Crystallization and preliminary X-ray crystallographic analysis of UDP-N-acetylglucosamine acyltransferase from Helicobacter pylori.
2002 May
Formation of methylantimony species by an aerobic prokaryote: Flavobacterium sp.
2002 Oct
Symmetric and helical growth of polyacetylene fibers over a single copper crystal derived from copper tartrate decomposition.
2002 Sep 5
Patents

Sample Use Guides

L-(+)-tartaric acid as a food additive. Acceptable Daily Intake: 0-30 mg/kg
Route of Administration: Oral
In Vitro Use Guide
After incubation in medium containing 50 mM L(+)-tartaric acid, osteoclasts and chondroclasts were heavily stained with reaction product.
Substance Class Chemical
Created
by admin
on Wed Jul 05 22:51:09 UTC 2023
Edited
by admin
on Wed Jul 05 22:51:09 UTC 2023
Record UNII
8F0G0F8I3B
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
AMMONIUM BITARTRATE
MI  
Systematic Name English
(2R,3R)-2,3-DIHYDROXYBUTANEDIOIC ACID AMMONIUM SALT (1:1)
Common Name English
L-TARTARIC ACID MONOAMMONIUM SALT
Common Name English
AMMONIUM BITARTRATE [MI]
Common Name English
Code System Code Type Description
EPA CompTox
DTXSID40883950
Created by admin on Wed Jul 05 22:51:09 UTC 2023 , Edited by admin on Wed Jul 05 22:51:09 UTC 2023
PRIMARY
CAS
3095-65-6
Created by admin on Wed Jul 05 22:51:09 UTC 2023 , Edited by admin on Wed Jul 05 22:51:09 UTC 2023
PRIMARY
ECHA (EC/EINECS)
221-442-2
Created by admin on Wed Jul 05 22:51:09 UTC 2023 , Edited by admin on Wed Jul 05 22:51:09 UTC 2023
PRIMARY
PUBCHEM
18352
Created by admin on Wed Jul 05 22:51:09 UTC 2023 , Edited by admin on Wed Jul 05 22:51:09 UTC 2023
PRIMARY
MERCK INDEX
M1770
Created by admin on Wed Jul 05 22:51:09 UTC 2023 , Edited by admin on Wed Jul 05 22:51:09 UTC 2023
PRIMARY Merck Index
FDA UNII
8F0G0F8I3B
Created by admin on Wed Jul 05 22:51:09 UTC 2023 , Edited by admin on Wed Jul 05 22:51:09 UTC 2023
PRIMARY
Related Record Type Details
PARENT -> SALT/SOLVATE