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Details

Stereochemistry ABSOLUTE
Molecular Formula C4H5O6.H4N
Molecular Weight 167.1174
Optical Activity UNSPECIFIED
Defined Stereocenters 2 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of AMMONIUM BITARTRATE

SMILES

[NH4+].O[C@H]([C@@H](O)C([O-])=O)C(O)=O

InChI

InChIKey=ZMFVLYPTTFPBNG-ZVGUSBNCSA-N
InChI=1S/C4H6O6.H3N/c5-1(3(7)8)2(6)4(9)10;/h1-2,5-6H,(H,7,8)(H,9,10);1H3/t1-,2-;/m1./s1

HIDE SMILES / InChI

Molecular Formula C4H6O6
Molecular Weight 150.0868
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 2 / 2
E/Z Centers 0
Optical Activity UNSPECIFIED

Molecular Formula H3N
Molecular Weight 17.0305
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Tartaric acid is found in many plants such as grapes, tamarinds, pineapples, mulberries and so on. Wine lees (called mud in the US), the sediment collected during the fermentation of grapes, contains potassium bitartrate (potassium hydrogen tartrate) as its major component. L-(+)-tartaric acid is an enantiomer of tartaric acid. Twenty five years before the tetrahedral structure for carbon was proposed in 1874 to explain the optical activity and other properties of organic compounds, Louis Pasteur discovered the existence of enantiomerism in tartaric acid. L-(+)-tartaric acid is widely used in food and beverage as acidity regulator with E number E334.

Originator

Curator's Comment: Scheele first prepared tartaric acid. Louis Pasteur discovered the existence of enantiomerism in tartaric acid

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Inactive ingredient
CLEARASIL DAILY CLEAR CLEAR SKIN

Approved Use

Unknown
Sourcing

Sourcing

Vendor/AggregatorIDURL
PubMed

PubMed

TitleDatePubMed
Vitreous concentration of topically applied brimonidine tartrate 0.2%.
2001 Apr
A novel and simplified route to the synthesis of N3S chelators for 99mTc labeling.
2001 Aug
Synthesis and evaluation of a C-glycosyl nucleoside as an inhibitor of chitin synthase.
2001 Aug 30
Reversal of multidrug resistance-associated protein-mediated drug resistance in cultured human neuroblastoma cells by the quinolone antibiotic difloxacin.
2001 Jan
Cell-surface recognition of biotinylated membrane proteins requires very long spacer arms: an example from glucose-transporter probes.
2001 Jan 8
Comparison of the clinical success and quality-of-life impact of brimonidine 0.2% and betaxolol 0.25 % suspension in patients with elevated intraocular pressure.
2001 Jul
Malo-ethanolic fermentation in grape must by recombinant strains of Saccharomyces cerevisiae.
2001 Jul
Arsenic induces expression of the multidrug resistance-associated protein 2 (MRP2) gene in primary rat and human hepatocytes.
2001 Jul
A Mg-dependent ecto-ATPase in Leishmania amazonensis and its possible role in adenosine acquisition and virulence.
2001 Jul 1
Stability of chiral domains produced by adsorption of tartaric acid isomers on the Cu(110) surface: a periodic density functional theory study.
2001 Jul 11
Isolation and characterization of Mn(III) tartrate from Phanerochaete chrysosporium culture broth.
2001 Jul 24
Stabilization of minodronic acid in aqueous solution for parenteral formulation.
2001 Jul 3
Determination of organic acids of low molecular weight and phosphate in soil by capillary electrophoresis.
2001 Jul-Aug
Dicaffeoyl- or digalloyl pyrrolidine and furan derivatives as HIV integrase inhibitors.
2001 Jun
Diverging respiratory effects of serotonin and nicotine in vagotomised cats prior to and after section of carotid sinus nerves.
2001 Mar
Crystal structure analysis and chiral recognition study of Delta-[Ru(bpy)2(py)2][(+)-O,O'-dibenzoylD-tartrate].12H2O and Lambda-[Ru(bpy)2(py)2][(-)-O,O'-dibenzoyl-L-tartrate].12H2O.
2001 Mar 12
Mutation of a single conserved tryptophan in multidrug resistance protein 1 (MRP1/ABCC1) results in loss of drug resistance and selective loss of organic anion transport.
2001 May 11
Technetium-99m direct radiolabeling of lanreotide: a somatostatin analog.
2001 Nov
Direct chiral resolution of tartaric acid in food products by ligand exchange capillary electrophoresis using copper(II)-D-quinic acid as a chiral selector.
2001 Oct 12
Direct chiral resolution of malic acid in apple juice by ligand-exchange capillary electrophoresis using copper(II)-L-tartaric acid as a chiral selector.
2001 Sep
Oxidation of hydroquinones by the versatile ligninolytic peroxidase from Pleurotus eryngii. H2O2 generation and the influence of Mn2+.
2001 Sep
Sodium stibogluconate is a potent inhibitor of protein tyrosine phosphatases and augments cytokine responses in hemopoietic cell lines.
2001 Sep 15
Towards atomic resolution with crystals grown in gel: the case of thaumatin seen at room temperature.
2002 Aug 1
Retention of anions on silica-based metalloporphyrin stationary phases.
2002 Feb
Ergotamine-induced anorectal strictures: report of five cases.
2002 Feb
Fibroblasts from the inner granulation tissue of the pseudocapsule in hips at revision arthroplasty induce osteoclast differentiation, as do stromal cells.
2002 Feb
Selective estrogen receptor modulators as a new therapeutic drug group: concept to reality in a decade.
2002 Jan
Anaerobaculum mobile sp. nov., a novel anaerobic, moderately thermophilic, peptide-fermenting bacterium that uses crotonate as an electron acceptor, and emended description of the genus Anaerobaculum.
2002 Jan
A simple spectrophotometric method for the determination of copper in industrial, environmental, biological and soil samples using 2,5-dimercapto-1,3,4-thiadiazole.
2002 Jul
High frequency of phenotypic deviations in Physcomitrella patens plants transformed with a gene-disruption library.
2002 Jul 18
Boronic acid receptors for alpha-hydroxycarboxylates: high affinity of Shinkai's glucose receptor for tartrate.
2002 Jul 26
Engineering the substrate specificity of D-amino-acid oxidase.
2002 Jul 26
Improving the labeling of S-acetyl NHS-MAG(3)-conjugated morpholino oligomers.
2002 Jul-Aug
Stereoselective radical reactions of some tartaric and glyceric acid derivatives.
2002 Jun 13
Recruitment, augmentation and apoptosis of rat osteoclasts in 1,25-(OH)2D3 response to short-term treatment with 1,25-dihydroxyvitamin D3 in vivo.
2002 Jun 7
Consumption of an omega-3 fatty acids product, INCELL AAFA, reduced side-effects of CPT-11 (irinotecan) in mice.
2002 Mar 18
Release of an acid phosphatase activity during lily pollen tube growth involves components of the secretory pathway.
2002 May
Crystallization and preliminary X-ray crystallographic analysis of UDP-N-acetylglucosamine acyltransferase from Helicobacter pylori.
2002 May
Potassium antimonyl tartrate induces reactive oxygen species-related apoptosis in human myeloid leukemic HL60 cells.
2002 May
Synovial macrophage-osteoclast differentiation in inflammatory arthritis.
2002 Oct
Ectonucleotide diphosphohydrolase activity in Crithidia deanei.
2002 Oct
Effects of sigma(1) receptor ligand MS-377 on D(2) antagonists-induced behaviors.
2002 Oct
Development of high-affinity ligands and photoaffinity labels for the D-fructose transporter GLUT5.
2002 Oct 15
Large scale gene expression analysis of osteoclastogenesis in vitro and elucidation of NFAT2 as a key regulator.
2002 Oct 25
Patents

Sample Use Guides

L-(+)-tartaric acid as a food additive. Acceptable Daily Intake: 0-30 mg/kg
Route of Administration: Oral
In Vitro Use Guide
After incubation in medium containing 50 mM L(+)-tartaric acid, osteoclasts and chondroclasts were heavily stained with reaction product.
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:20:25 GMT 2023
Edited
by admin
on Fri Dec 15 15:20:25 GMT 2023
Record UNII
8F0G0F8I3B
Record Status Validated (UNII)
Record Version
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Name Type Language
AMMONIUM BITARTRATE
MI  
Systematic Name English
(2R,3R)-2,3-DIHYDROXYBUTANEDIOIC ACID AMMONIUM SALT (1:1)
Common Name English
L-TARTARIC ACID MONOAMMONIUM SALT
Common Name English
AMMONIUM BITARTRATE [MI]
Common Name English
Code System Code Type Description
EPA CompTox
DTXSID40883950
Created by admin on Fri Dec 15 15:20:25 GMT 2023 , Edited by admin on Fri Dec 15 15:20:25 GMT 2023
PRIMARY
CAS
3095-65-6
Created by admin on Fri Dec 15 15:20:25 GMT 2023 , Edited by admin on Fri Dec 15 15:20:25 GMT 2023
PRIMARY
ECHA (EC/EINECS)
221-442-2
Created by admin on Fri Dec 15 15:20:25 GMT 2023 , Edited by admin on Fri Dec 15 15:20:25 GMT 2023
PRIMARY
PUBCHEM
18352
Created by admin on Fri Dec 15 15:20:25 GMT 2023 , Edited by admin on Fri Dec 15 15:20:25 GMT 2023
PRIMARY
MERCK INDEX
m1770
Created by admin on Fri Dec 15 15:20:25 GMT 2023 , Edited by admin on Fri Dec 15 15:20:25 GMT 2023
PRIMARY Merck Index
FDA UNII
8F0G0F8I3B
Created by admin on Fri Dec 15 15:20:25 GMT 2023 , Edited by admin on Fri Dec 15 15:20:25 GMT 2023
PRIMARY
Related Record Type Details
PARENT -> SALT/SOLVATE