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Details

Stereochemistry ACHIRAL
Molecular Formula C12H12N2.ClH
Molecular Weight 220.698
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of BENZIDINE MONOHYDROCHLORIDE

SMILES

Cl.NC1=CC=C(C=C1)C2=CC=C(N)C=C2

InChI

InChIKey=FYRTZXXTIDKEJD-UHFFFAOYSA-N
InChI=1S/C12H12N2.ClH/c13-11-5-1-9(2-6-11)10-3-7-12(14)8-4-10;/h1-8H,13-14H2;1H

HIDE SMILES / InChI

Molecular Formula C12H12N2
Molecular Weight 184.2371
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula ClH
Molecular Weight 36.461
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
[Express method of determining blood in the abdominal cavity in closed abdominal injuries].
2001
Detection of fetal erythroid cells from maternal blood using fluorescence in situ hybridization and liquid culture.
2001 Apr
Using base-specific Salmonella tester strains to characterize the types of mutation induced by benzidine and benzidine congeners after reductive metabolism.
2001 Dec
Synthesis of C8-adenosine adducts of arylamines using palladium catalysis.
2001 Dec 27
Biomarker risk assessment and bladder cancer detection in a cohort exposed to benzidine.
2001 Mar 21
Dependence of papanicolaou gradings of exfoliated urothelial cells upon GSTM1 and GSTT1 polymorphism in benzidine-exposed workers of the Shanghai dye industry.
2001 Nov
[Fluorescence development of blood fingerprint].
2001 Oct
Re: Biomarker risk assessment and bladder cancer detection in a cohort exposed to benzidine.
2001 Oct 3
Evaluation of opioid receptors in synovial membranes of horses.
2001 Sep
Effects of Matrine on proliferation and differentiation in K-562 cells.
2001 Sep
Benzidine.
2002
Ultrastructural localization of light-induced lipid peroxides.
2002
How many food additives are rodent carcinogens?
2002
Binding mode analysis of 3-(4-benzoyl-1-methyl-1H-2-pyrrolyl)-N-hydroxy-2-propenamide: a new synthetic histone deacetylase inhibitor inducing histone hyperacetylation, growth inhibition, and terminal cell differentiation.
2002 Apr 25
Co-transfection of p16(INK4a) and p53 genes into the K562 cell line inhibits cell proliferation.
2002 Feb
The effect of proteasome inhibitors on mammalian erythroid terminal differentiation.
2002 Jul
Anaerobic reduction of a sulfonated azo dye, Congo Red, by sulfate-reducing bacteria.
2002 Mar
Harmful azo colorants in leather. Determination based on their cleavage and extraction of corresponding carcinogenic aromatic amines using modern extraction techniques.
2002 May 10
Organic analysis by ion chromatography. 1. Determination of aromatic amines and aromatic diisocyanates by cation-exchange chromatography with amperometric detection.
2002 May 17
Biodegradation of benzidine based azodyes Direct red and Direct blue by the immobilized cells of Pseudomonas fluorescens D41.
2002 Oct
[Effects of SCL antisense ooligonucleotides on K562 and CEM cell lines].
2002 Oct
Semiconductor-mediated photocatalysed degradation of two selected priority organic pollutants, benzidine and 1,2-diphenylhydrazine, in aqueous suspension.
2002 Oct
A light and electron microscopic study of the mouse visceral yolk sac endodermal cells in the middle and late embryonic periods, showing the possibility of definitive erythropoiesis.
2002 Sep
Mutant spectra analysis at hisG46 in Salmonella typhimurium strain YG1029 induced by mammalian S9- and plant-activated aromatic amines.
2003
Immobilization of thermolysin to polyamide nonwoven materials.
2003 Apr 20
New sensitive determination method of benzidine-hemoglobin adducts by gas chromatography-electron impact mass spectrometry.
2003 Jan 5
[Aromatic amines with certain, probable, or possible carcinogenic action: reference values].
2003 Jan-Mar
Markers of genetic susceptibility in human environmental hygiene and toxicology: the role of selected CYP, NAT and GST genes.
2003 Jun
Separation and trace estimation of benzidine and its macromolecular adducts using supercritical fluid chromatography.
2003 Oct 5
Evaluation of anti-prion activity of congo red and its derivatives in experimentally infected hamsters.
2004
Lactoperoxidase-catalyzed activation of carcinogenic aromatic and heterocyclic amines.
2004 Dec
Optimization of an analytical method for detecting paraphenylenediamine (PPD) by GC/MS-iontrap in biological liquids.
2004 Dec 2
Oxidation of benzidine and its derivatives by thyroid peroxidase.
2004 Feb
Occupational exposure and urological cancer.
2004 Feb
Comparative metabolic activation of benzidine and N-acetylbenzidine by prostaglandin H synthase.
2004 Jun 15
Assessment of the performance of the Ames II assay: a collaborative study with 19 coded compounds.
2004 Mar 14
Surface-modified mesoporous ceramics as delivery vehicle for haemoglobin.
2004 May-Jun
Listing occupational carcinogens.
2004 Nov
Cancer mortality and incidence among a cohort of benzidine and dichlorobenzidine dye manufacturing workers.
2004 Nov
Production of hemo- and immunoregulatory cytokines by erythroblast antigen+ and glycophorin A+ cells from human bone marrow.
2004 Oct 18
Alkylaniline-hemoglobin adducts and risk of non-smoking-related bladder cancer.
2004 Oct 6
Polymorphism of N-acetyltransferase 2 (NAT2) gene polymorphism in shanghai population: occupational and non-occupational bladder cancer patient groups.
2004 Sep
Morphology, cytochemical staining, and ultrastructural characteristics of the blood cells of the giant lizard of El Hierro (Gallotia simonyi).
2005 Apr
[Effect of specific siRNA targeting against bcr-abl chimeric gene on chronic myelogenous leukemia cells].
2005 Jan 19
The formation of cucurbit[n]uril (n = 6, 7) complexes with amino compounds in aqueous formic acid studied by capillary electrophoresis.
2005 Jun
Patents
Substance Class Chemical
Created
by admin
on Fri Dec 15 18:50:02 GMT 2023
Edited
by admin
on Fri Dec 15 18:50:02 GMT 2023
Record UNII
8CT94058SV
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
BENZIDINE MONOHYDROCHLORIDE
Systematic Name English
(1,1'-BIPHENYL)-4,4'-DIAMINE, HYDROCHLORIDE (1:1)
Systematic Name English
(1,1'-BIPHENYL)-4,4'-DIAMINE, MONOHYDROCHLORIDE
Common Name English
(1,1'-BIPHENYL)-4,4'-DIAMINE, HYDROCHLORIDE
Systematic Name English
Code System Code Type Description
PUBCHEM
61741
Created by admin on Fri Dec 15 18:50:02 GMT 2023 , Edited by admin on Fri Dec 15 18:50:02 GMT 2023
PRIMARY
CAS
14414-68-7
Created by admin on Fri Dec 15 18:50:02 GMT 2023 , Edited by admin on Fri Dec 15 18:50:02 GMT 2023
NON-SPECIFIC STOICHIOMETRY
FDA UNII
8CT94058SV
Created by admin on Fri Dec 15 18:50:02 GMT 2023 , Edited by admin on Fri Dec 15 18:50:02 GMT 2023
PRIMARY
CAS
75752-15-7
Created by admin on Fri Dec 15 18:50:02 GMT 2023 , Edited by admin on Fri Dec 15 18:50:02 GMT 2023
PRIMARY
Related Record Type Details
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