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Details

Stereochemistry ACHIRAL
Molecular Formula C19H38O2
Molecular Weight 298.5038
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of Isopropyl palmitate

SMILES

CCCCCCCCCCCCCCCC(=O)OC(C)C

InChI

InChIKey=XUGNVMKQXJXZCD-UHFFFAOYSA-N
InChI=1S/C19H38O2/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-19(20)21-18(2)3/h18H,4-17H2,1-3H3

HIDE SMILES / InChI
Molecular Formula C19H38O2
Molecular Weight 298.5038
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description
Curator's Comment: Description was created based on several sources, including https://www.carecreations.basf.com/product-formulations/products/products-detail/ISOPROPYL%20PALMITATE/30528720 and http://www.ncbi.nlm.nih.gov/pubmed/17077540

Isopropyl palmitate is the ester of isopropyl alcohol and palmitic acid. It is an emollient, moisturizer, thickening agent, and anti-static agent. Isopropyl Palmitate is a traditional, fast spreading emollient for modern cosmetic applications. Isopropyl palmitate is approved by ECOCERT for Natural and Organic Cosmetics. It is on FDA CFR - Code of Federal Regulations Title 21 list.

Approval Year

1996
224
Targets

Targets

Primary TargetPharmacologyConditionPotency
Inhibitor
8504
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Sourcing

Sourcing

Vendor/AggregatorIDURL
ChEBI
CHEBI:84262
https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:84262
ChemicalBook
CB0451826
https://www.chemicalbook.com/ChemicalProductProperty_EN_CB0451826
eMolecules
495289
https://www.emolecules.com/cgi-bin/more?vid=495289
MolPort
MolPort-003-929-332
https://www.molport.com/shop/molecule-link/MolPort-003-929-332
ZINC
ZINC000008214589
http://zinc15.docking.org/substances/ZINC000008214589
PubMed

PubMed

TitleDatePubMed
Pluronic lecithin organogel as a topical drug delivery system.
2010-01
Foreign body reaction to bone wax an unusual cause of persistent serous discharge from iliac crest graft donor site and the possible means to avoid such complication - a case report.
2009-11-27
Microemulsions as a surrogate carrier for dermal drug delivery.
2009-05
Topical delivery of flurbiprofen from pluronic lecithin organogel.
2009-01
The role of capillary force promoters in dry coating procedures--evaluation of acetylated monoglyceride, isopropyl myristate and palmitate.
2009-01
Aerosol OT microemulsions as carriers for transdermal delivery of hydrophobic and hydrophilic local anesthetics.
2008-06
Assessment of oil polarity: comparison of evaluation methods.
2008-02-04
Use of bone wax during laparoscopic renal ablative procedures: optimizing port utilization and reducing tract-site exposure.
2008-02-02
Infection rates and healing using bone wax and a soluble polymer material.
2008-02
Preparation and evaluation of diltiazem hydrochloride diffusion-controlled transdermal delivery system.
2008
[Screening of Panax notoginsenoside water in oil microemulsion formulations and their evaluation in vitro and in vivo].
2007-07
Effect of penetration enhancers on skin permeation of trazodone hydrochloride from matrix type transdermal formulation through mouse and human cadaver epidermis.
2007-04-19
Lecithin organogels used as bioactive compounds carriers. A microdomain properties investigation.
2007-04-10
Comedogenicity in rabbit: some cosmetic ingredients/vehicles.
2007
Transdermal delivery of hydrophobic and hydrophilic local anesthetics from o/w and w/o Brij 97-based microemulsions.
2007
Transdermal permeability of N-acetyl-D-glucosamine.
2007
Microemulsions as transdermal drug delivery vehicles.
2006-11-16
Investigation of fatty acid esters to replace isopropyl myristate in the sterility test for ophthalmic ointments.
2006-11-16
Characterisation of microstructures formed in isopropyl palmitate/water/Aerosol OT:1-butanol (2:1) system.
2006-11
Effects of isopropyl palmitate on the skin permeation of drugs.
2006-11
The hairless guinea-pig as a model for treatment of acute irritation in humans.
2006-08
Effect of oil phase lipophilicity on in vitro drug release from o/w microemulsions with low surfactant content.
2006-06
Characterization of microemulsion structures in the pseudoternary phase diagram of isopropyl palmitate/water/Brij 97:1-butanol.
2006-05-12
The hairless guinea-pig as a model for treatment of cumulative irritation in humans.
2006-02
[Analysis of constituents of essential oil from the skin of water caltrop].
2006-01
Biocompatible lecithin organogels: structure and phase equilibria.
2005-01-04
Microemulsions for dermal drug delivery studied by dynamic light scattering: effect of interparticle interactions in oil-in-water microemulsions.
2003-04
Effect of hydrophobic permeation enhancers on the release and skin permeation kinetics from matrix type transdermal drug delivery system of ketotifen fumarate.
2001-08-15
Patents

Patents

04336243
1
JP2000119178A
1
JP2003519659A
1
JPH0565218A
1
JPH0930964A
1
JPH1135448A
1
JPS62298526A
7

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Isopropyl palmitate inhibited 44% of N-palmitoylethanolamine-selective acid amidase (NPAA) from rat lung homogenates at 100 uM
Substance Class Chemical
Created
by admin
on Mon Mar 31 17:35:06 GMT 2025
Edited
by admin
on Mon Mar 31 17:35:06 GMT 2025
Record UNII
8CRQ2TH63M
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
NSC-69169
Preferred Name English
Isopropyl palmitate
EP   HSDB   II   INCI   MART.   USP-RS   VANDF   WHO-DD  
INCI  
Official Name English
Isopropyl palmitate [WHO-DD]
Common Name English
ESTOL 1517
Brand Name English
ISOPROPYL PALMITATE [II]
Common Name English
HARIOL IPP
Common Name English
HEXADECANOIC ACID, 1-METHYLETHYL ESTER
Common Name English
ISOPROPYL PALMITATE [MART.]
Common Name English
EMEREST 2316
Brand Name English
ISOPROPYL PALMITATE [USP-RS]
Common Name English
ISOPROPYL PALMITATE [EP MONOGRAPH]
Common Name English
ISOPROPYL PALMITATE [HSDB]
Common Name English
PALMITIC ACID, ISOPROPYL ESTER
Common Name English
ISOPROPYL HEXADECANOATE
Systematic Name English
ISOPROPYL PALMITATE [EP IMPURITY]
Common Name English
WICKENOL 111
Brand Name English
ISOPROPYL PALMITATE [VANDF]
Common Name English
Classification Tree Code System Code
EPA PESTICIDE CODE 208
Created by admin on Mon Mar 31 17:35:06 GMT 2025 , Edited by admin on Mon Mar 31 17:35:06 GMT 2025
Code System Code Type Description
CAS
142-91-6
Created by admin on Mon Mar 31 17:35:06 GMT 2025 , Edited by admin on Mon Mar 31 17:35:06 GMT 2025
PRIMARY
NCI_THESAURUS
C45678
Created by admin on Mon Mar 31 17:35:06 GMT 2025 , Edited by admin on Mon Mar 31 17:35:06 GMT 2025
CONCEPT Industrial Aid
MESH
C005060
Created by admin on Mon Mar 31 17:35:06 GMT 2025 , Edited by admin on Mon Mar 31 17:35:06 GMT 2025
PRIMARY
EPA CompTox
DTXSID9027104
Created by admin on Mon Mar 31 17:35:06 GMT 2025 , Edited by admin on Mon Mar 31 17:35:06 GMT 2025
PRIMARY
FDA UNII
8CRQ2TH63M
Created by admin on Mon Mar 31 17:35:06 GMT 2025 , Edited by admin on Mon Mar 31 17:35:06 GMT 2025
PRIMARY
WIKIPEDIA
ISOPROPYL PALMITATE
Created by admin on Mon Mar 31 17:35:06 GMT 2025 , Edited by admin on Mon Mar 31 17:35:06 GMT 2025
PRIMARY
ECHA (EC/EINECS)
205-571-1
Created by admin on Mon Mar 31 17:35:06 GMT 2025 , Edited by admin on Mon Mar 31 17:35:06 GMT 2025
PRIMARY
RS_ITEM_NUM
1350603
Created by admin on Mon Mar 31 17:35:06 GMT 2025 , Edited by admin on Mon Mar 31 17:35:06 GMT 2025
PRIMARY
ChEMBL
CHEMBL139055
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PRIMARY
HSDB
2647
Created by admin on Mon Mar 31 17:35:06 GMT 2025 , Edited by admin on Mon Mar 31 17:35:06 GMT 2025
PRIMARY
DAILYMED
8CRQ2TH63M
Created by admin on Mon Mar 31 17:35:06 GMT 2025 , Edited by admin on Mon Mar 31 17:35:06 GMT 2025
PRIMARY
SMS_ID
100000077587
Created by admin on Mon Mar 31 17:35:06 GMT 2025 , Edited by admin on Mon Mar 31 17:35:06 GMT 2025
PRIMARY
NSC
69169
Created by admin on Mon Mar 31 17:35:06 GMT 2025 , Edited by admin on Mon Mar 31 17:35:06 GMT 2025
PRIMARY
CHEBI
84262
Created by admin on Mon Mar 31 17:35:06 GMT 2025 , Edited by admin on Mon Mar 31 17:35:06 GMT 2025
PRIMARY
EVMPD
SUB14282MIG
Created by admin on Mon Mar 31 17:35:06 GMT 2025 , Edited by admin on Mon Mar 31 17:35:06 GMT 2025
PRIMARY
RXCUI
1311179
Created by admin on Mon Mar 31 17:35:06 GMT 2025 , Edited by admin on Mon Mar 31 17:35:06 GMT 2025
PRIMARY RxNorm
NCI_THESAURUS
C76718
Created by admin on Mon Mar 31 17:35:06 GMT 2025 , Edited by admin on Mon Mar 31 17:35:06 GMT 2025
PRIMARY
PUBCHEM
8907
Created by admin on Mon Mar 31 17:35:06 GMT 2025 , Edited by admin on Mon Mar 31 17:35:06 GMT 2025
PRIMARY
Related Record Type Details
Structure of Isopropyl palmitate
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