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Details

Stereochemistry ACHIRAL
Molecular Formula C19H38O2
Molecular Weight 298.5038
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of Isopropyl palmitate

SMILES

CCCCCCCCCCCCCCCC(=O)OC(C)C

InChI

InChIKey=XUGNVMKQXJXZCD-UHFFFAOYSA-N
InChI=1S/C19H38O2/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-19(20)21-18(2)3/h18H,4-17H2,1-3H3

HIDE SMILES / InChI
Molecular Formula C19H38O2
Molecular Weight 298.5038
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description
Curator's Comment: Description was created based on several sources, including https://www.carecreations.basf.com/product-formulations/products/products-detail/ISOPROPYL%20PALMITATE/30528720 and http://www.ncbi.nlm.nih.gov/pubmed/17077540

Isopropyl palmitate is the ester of isopropyl alcohol and palmitic acid. It is an emollient, moisturizer, thickening agent, and anti-static agent. Isopropyl Palmitate is a traditional, fast spreading emollient for modern cosmetic applications. Isopropyl palmitate is approved by ECOCERT for Natural and Organic Cosmetics. It is on FDA CFR - Code of Federal Regulations Title 21 list.

Approval Year

1996
225
Targets

Targets

Primary TargetPharmacologyConditionPotency
Inhibitor
8297
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Sourcing

Sourcing

Vendor/AggregatorIDURL
ChEBI
CHEBI:84262
https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:84262
ChemicalBook
CB0451826
https://www.chemicalbook.com/ChemicalProductProperty_EN_CB0451826
MolPort
MolPort-003-929-332
https://www.molport.com/shop/molecule-link/MolPort-003-929-332
ZINC
ZINC000008214589
http://zinc15.docking.org/substances/ZINC000008214589
eMolecules
495289
https://www.emolecules.com/cgi-bin/more?vid=495289
PubMed

PubMed

TitleDatePubMed
Effect of hydrophobic permeation enhancers on the release and skin permeation kinetics from matrix type transdermal drug delivery system of ketotifen fumarate.
2001 Mar-Apr
Microemulsions for dermal drug delivery studied by dynamic light scattering: effect of interparticle interactions in oil-in-water microemulsions.
2003 Apr
Biocompatible lecithin organogels: structure and phase equilibria.
2005 Jan 4
The hairless guinea-pig as a model for treatment of acute irritation in humans.
2006 Aug
The hairless guinea-pig as a model for treatment of cumulative irritation in humans.
2006 Feb
[Analysis of constituents of essential oil from the skin of water caltrop].
2006 Jan
Effect of oil phase lipophilicity on in vitro drug release from o/w microemulsions with low surfactant content.
2006 Jun
Characterization of microemulsion structures in the pseudoternary phase diagram of isopropyl palmitate/water/Brij 97:1-butanol.
2006 May 12
Characterisation of microstructures formed in isopropyl palmitate/water/Aerosol OT:1-butanol (2:1) system.
2006 Nov
Effects of isopropyl palmitate on the skin permeation of drugs.
2006 Nov
Microemulsions as transdermal drug delivery vehicles.
2006 Nov 16
Investigation of fatty acid esters to replace isopropyl myristate in the sterility test for ophthalmic ointments.
2006 Nov 16
Effect of penetration enhancers on skin permeation of trazodone hydrochloride from matrix type transdermal formulation through mouse and human cadaver epidermis.
2006 Nov-Dec
Transdermal delivery of hydrophobic and hydrophilic local anesthetics from o/w and w/o Brij 97-based microemulsions.
2007
Transdermal permeability of N-acetyl-D-glucosamine.
2007
Lecithin organogels used as bioactive compounds carriers. A microdomain properties investigation.
2007 Apr 10
Use of bone wax during laparoscopic renal ablative procedures: optimizing port utilization and reducing tract-site exposure.
2007 Oct-Dec
Aerosol OT microemulsions as carriers for transdermal delivery of hydrophobic and hydrophilic local anesthetics.
2008 Jun
Topical delivery of flurbiprofen from pluronic lecithin organogel.
2009 Jan
Microemulsions as a surrogate carrier for dermal drug delivery.
2009 May
Foreign body reaction to bone wax an unusual cause of persistent serous discharge from iliac crest graft donor site and the possible means to avoid such complication - a case report.
2009 Nov 27
Pluronic lecithin organogel as a topical drug delivery system.
2010 Jan
Patents

Patents

04336243
1
JP2000119178A
1
JP2003519659A
1
JPH0565218A
1
JPH0930964A
1
JPH1135448A
1
JPS62298526A
7

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Isopropyl palmitate inhibited 44% of N-palmitoylethanolamine-selective acid amidase (NPAA) from rat lung homogenates at 100 uM
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:00:42 GMT 2023
Edited
by admin
on Fri Dec 15 15:00:42 GMT 2023
Record UNII
8CRQ2TH63M
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
Isopropyl palmitate
EP   HSDB   II   INCI   MART.   USP-RS   VANDF   WHO-DD  
INCI  
Official Name English
Isopropyl palmitate [WHO-DD]
Common Name English
ESTOL 1517
Brand Name English
ISOPROPYL PALMITATE [II]
Common Name English
HARIOL IPP
Common Name English
HEXADECANOIC ACID, 1-METHYLETHYL ESTER
Common Name English
ISOPROPYL PALMITATE [MART.]
Common Name English
EMEREST 2316
Brand Name English
ISOPROPYL PALMITATE [USP-RS]
Common Name English
ISOPROPYL PALMITATE [INCI]
Common Name English
ISOPROPYL PALMITATE [EP MONOGRAPH]
Common Name English
ISOPROPYL PALMITATE [HSDB]
Common Name English
NSC-69169
Code English
PALMITIC ACID, ISOPROPYL ESTER
Common Name English
ISOPROPYL HEXADECANOATE
Systematic Name English
ISOPROPYL PALMITATE [EP IMPURITY]
Common Name English
WICKENOL 111
Brand Name English
ISOPROPYL PALMITATE [VANDF]
Common Name English
Classification Tree Code System Code
EPA PESTICIDE CODE 208
Created by admin on Fri Dec 15 15:00:42 GMT 2023 , Edited by admin on Fri Dec 15 15:00:42 GMT 2023
Code System Code Type Description
CAS
142-91-6
Created by admin on Fri Dec 15 15:00:42 GMT 2023 , Edited by admin on Fri Dec 15 15:00:42 GMT 2023
PRIMARY
NCI_THESAURUS
C45678
Created by admin on Fri Dec 15 15:00:42 GMT 2023 , Edited by admin on Fri Dec 15 15:00:42 GMT 2023
CONCEPT Industrial Aid
MESH
C005060
Created by admin on Fri Dec 15 15:00:42 GMT 2023 , Edited by admin on Fri Dec 15 15:00:42 GMT 2023
PRIMARY
EPA CompTox
DTXSID9027104
Created by admin on Fri Dec 15 15:00:42 GMT 2023 , Edited by admin on Fri Dec 15 15:00:42 GMT 2023
PRIMARY
FDA UNII
8CRQ2TH63M
Created by admin on Fri Dec 15 15:00:42 GMT 2023 , Edited by admin on Fri Dec 15 15:00:42 GMT 2023
PRIMARY
WIKIPEDIA
ISOPROPYL PALMITATE
Created by admin on Fri Dec 15 15:00:42 GMT 2023 , Edited by admin on Fri Dec 15 15:00:42 GMT 2023
PRIMARY
ECHA (EC/EINECS)
205-571-1
Created by admin on Fri Dec 15 15:00:42 GMT 2023 , Edited by admin on Fri Dec 15 15:00:42 GMT 2023
PRIMARY
RS_ITEM_NUM
1350603
Created by admin on Fri Dec 15 15:00:42 GMT 2023 , Edited by admin on Fri Dec 15 15:00:42 GMT 2023
PRIMARY
ChEMBL
CHEMBL139055
Created by admin on Fri Dec 15 15:00:42 GMT 2023 , Edited by admin on Fri Dec 15 15:00:42 GMT 2023
PRIMARY
HSDB
2647
Created by admin on Fri Dec 15 15:00:42 GMT 2023 , Edited by admin on Fri Dec 15 15:00:42 GMT 2023
PRIMARY
DAILYMED
8CRQ2TH63M
Created by admin on Fri Dec 15 15:00:42 GMT 2023 , Edited by admin on Fri Dec 15 15:00:42 GMT 2023
PRIMARY
SMS_ID
100000077587
Created by admin on Fri Dec 15 15:00:42 GMT 2023 , Edited by admin on Fri Dec 15 15:00:42 GMT 2023
PRIMARY
NSC
69169
Created by admin on Fri Dec 15 15:00:42 GMT 2023 , Edited by admin on Fri Dec 15 15:00:42 GMT 2023
PRIMARY
CHEBI
84262
Created by admin on Fri Dec 15 15:00:42 GMT 2023 , Edited by admin on Fri Dec 15 15:00:42 GMT 2023
PRIMARY
EVMPD
SUB14282MIG
Created by admin on Fri Dec 15 15:00:42 GMT 2023 , Edited by admin on Fri Dec 15 15:00:42 GMT 2023
PRIMARY
RXCUI
1311179
Created by admin on Fri Dec 15 15:00:42 GMT 2023 , Edited by admin on Fri Dec 15 15:00:42 GMT 2023
PRIMARY RxNorm
NCI_THESAURUS
C76718
Created by admin on Fri Dec 15 15:00:42 GMT 2023 , Edited by admin on Fri Dec 15 15:00:42 GMT 2023
PRIMARY
PUBCHEM
8907
Created by admin on Fri Dec 15 15:00:42 GMT 2023 , Edited by admin on Fri Dec 15 15:00:42 GMT 2023
PRIMARY
Related Record Type Details
Structure of Isopropyl palmitate
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