Details
Stereochemistry | ABSOLUTE |
Molecular Formula | C14H17NO8 |
Molecular Weight | 327.2867 |
Optical Activity | UNSPECIFIED |
Defined Stereocenters | 5 / 5 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
CC(=O)NC1=CC=C(O[C@@H]2O[C@@H]([C@@H](O)[C@H](O)[C@H]2O)C(O)=O)C=C1
InChI
InChIKey=IPROLSVTVHAQLE-BYNIDDHOSA-N
InChI=1S/C14H17NO8/c1-6(16)15-7-2-4-8(5-3-7)22-14-11(19)9(17)10(18)12(23-14)13(20)21/h2-5,9-12,14,17-19H,1H3,(H,15,16)(H,20,21)/t9-,10-,11+,12-,14+/m0/s1
Molecular Formula | C14H17NO8 |
Molecular Weight | 327.2867 |
Charge | 0 |
Count |
|
Stereochemistry | ABSOLUTE |
Additional Stereochemistry | No |
Defined Stereocenters | 5 / 5 |
E/Z Centers | 0 |
Optical Activity | UNSPECIFIED |
Approval Year
PubMed
Title | Date | PubMed |
---|---|---|
Intracellular inhibition of UDP-glucose dehydrogenase during ethanol oxidation. | 1983 Mar |
|
Interindividual variability in acetaminophen glucuronidation by human liver microsomes: identification of relevant acetaminophen UDP-glucuronosyltransferase isoforms. | 2001 Dec |
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Cisapride raises the bioavailability of paracetamol by inhibiting its glucuronidation in man. | 2001 Jul |
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Type I diabetes mellitus does not alter initial splanchnic glucose extraction or hepatic UDP-glucose flux during enteral glucose administration. | 2001 Jun |
|
Immune thrombocytopenia resulting from sensitivity to metabolites of naproxen and acetaminophen. | 2001 Jun 15 |
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Effect of nizatidine on paracetamol and its metabolites in human plasma. | 2002 Jun |
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Transiently altered acetaminophen metabolism after liver transplantation. | 2003 Jun |
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Higher insulin concentrations are required to suppress gluconeogenesis than glycogenolysis in nondiabetic humans. | 2003 Sep |
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The quantification of paracetamol, paracetamol glucuronide and paracetamol sulphate in plasma and urine using a single high-performance liquid chromatography assay. | 2004 Feb 18 |
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Identification of phenacetin metabolites in human urine after administration of phenacetin-C2H3: measurement of futile metabolic deacetylation via HPLC/MS-SPE-NMR and HPLC-ToF MS. | 2006 Jul |
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Evidence that processes other than gluconeogenesis may influence the ratio of deuterium on the fifth and third carbons of glucose: implications for the use of 2H2O to measure gluconeogenesis in humans. | 2008 Jan |
|
Hepatic synthesis and urinary elimination of acetaminophen glucuronide are exacerbated in bile duct-ligated rats. | 2008 Mar |
|
Sources of hepatic glucose production by 2H2O ingestion and Bayesian analysis of 2H glucuronide enrichment. | 2008 Sep |
|
Simultaneous RP-HPLC determination of sotalol, metoprolol, alpha-hydroxymetoprolol, paracetamol and its glucuronide and sulfate metabolites in human urine. | 2009 Jun |
Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 04:37:23 UTC 2023
by
admin
on
Sat Dec 16 04:37:23 UTC 2023
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Record UNII |
8BE7G9R76X
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Record Status |
Validated (UNII)
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Record Version |
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-
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83944
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C037386
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32636
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8BE7G9R76X
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DTXSID30936449
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16110-10-4
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admin on Sat Dec 16 04:37:23 UTC 2023 , Edited by admin on Sat Dec 16 04:37:23 UTC 2023
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Related Record | Type | Details | ||
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SALT/SOLVATE -> PARENT |
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Related Record | Type | Details | ||
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PARENT -> METABOLITE INACTIVE |
MAJOR
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