Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C14H17NO8 |
| Molecular Weight | 327.2867 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 5 / 5 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC(=O)NC1=CC=C(O[C@@H]2O[C@@H]([C@@H](O)[C@H](O)[C@H]2O)C(O)=O)C=C1
InChI
InChIKey=IPROLSVTVHAQLE-BYNIDDHOSA-N
InChI=1S/C14H17NO8/c1-6(16)15-7-2-4-8(5-3-7)22-14-11(19)9(17)10(18)12(23-14)13(20)21/h2-5,9-12,14,17-19H,1H3,(H,15,16)(H,20,21)/t9-,10-,11+,12-,14+/m0/s1
| Molecular Formula | C14H17NO8 |
| Molecular Weight | 327.2867 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 5 / 5 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Cisapride raises the bioavailability of paracetamol by inhibiting its glucuronidation in man. | 2001 Jul |
|
| Type I diabetes mellitus does not alter initial splanchnic glucose extraction or hepatic UDP-glucose flux during enteral glucose administration. | 2001 Jun |
|
| Hepatobiliary excretion of acetaminophen glutathione conjugate and its derivatives in transport-deficient (TR-) hyperbilirubinemic rats. | 2003 Jun |
|
| Induction of multidrug resistance protein 3 in rat liver is associated with altered vectorial excretion of acetaminophen metabolites. | 2003 Sep |
|
| Altered disposition of acetaminophen in mice with a disruption of the Mrp3 gene. | 2005 Nov |
|
| Pathways of galactose metabolism by galactosemics: evidence for galactose conversion to hepatic UDPglucose. | 2006 Feb |
|
| A pharmacokinetic study of paracetamol in Thai beta-thalassemia/HbE patients. | 2006 Sep |
|
| Effects of combined UDP-glucuronosyltransferase (UGT) 1A1*28 and 1A6*2 on paracetamol pharmacokinetics in beta-thalassemia/HbE. | 2007 |
|
| Hepatic synthesis and urinary elimination of acetaminophen glucuronide are exacerbated in bile duct-ligated rats. | 2008 Mar |
|
| In vivo glucuronidation activity of drugs in neonates: extensive interindividual variability despite their young age. | 2009 Aug |
|
| Effect of repeated administration with subtoxic doses of acetaminophen to rats on enterohepatic recirculation of a subsequent toxic dose. | 2009 May 15 |
|
| Does rapid metabolism ensure negligible risk from bisphenol A? | 2009 Nov |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 04:37:23 GMT 2023
by
admin
on
Sat Dec 16 04:37:23 GMT 2023
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| Record UNII |
8BE7G9R76X
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| Record Status |
Validated (UNII)
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| Record Version |
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83944
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C037386
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32636
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8BE7G9R76X
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DTXSID30936449
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16110-10-4
Created by
admin on Sat Dec 16 04:37:23 GMT 2023 , Edited by admin on Sat Dec 16 04:37:23 GMT 2023
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| Related Record | Type | Details | ||
|---|---|---|---|---|
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SALT/SOLVATE -> PARENT |
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| Related Record | Type | Details | ||
|---|---|---|---|---|
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PARENT -> METABOLITE INACTIVE |
MAJOR
URINE
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