CARPIPRAMINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C28H38N4O
Molecular Weight	446.6275
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

NC(=O)C1(CCN(CCCN2C3=C(CCC4=C2C=CC=C4)C=CC=C3)CC1)N5CCCCC5

InChI

InChIKey=NWPJLRSCSQHPJV-UHFFFAOYSA-N

InChI=1S/C28H38N4O/c29-27(33)28(31-18-6-1-7-19-31)15-21-30(22-16-28)17-8-20-32-25-11-4-2-9-23(25)13-14-24-10-3-5-12-26(24)32/h2-5,9-12H,1,6-8,13-22H2,(H2,29,33)

HIDE SMILES / InChI

Molecular Formula	C28H38N4O
Molecular Weight	446.6275
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: http://ansm.sante.fr/S-informer/Informations-de-securite-Lettres-aux-professionnels-de-sante/PRAZINIL-50mg-carpipramine-comprime-pellicule-retrait-de-son-autorisation-de-mise-sur-le-marche-a-compter-du-2-septembre-2014-Lettre-aux-professionnels-de-sante

Carpipramine (Prazinil, Defekton) is an atypical antipsychotic used for the treatment of schizophrenia and anxiety in France and Japan. In addition to its neuroleptic and anxiolytic effects, carpipramine also has hypnotic properties. In september 2014 L'ANSM decided to withdraw the marketing of Prazinil (carpipramine).

Originator

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Schizophrenia 298 Sources: https://www.ncbi.nlm.nih.gov/pubmed/19231	Primary		Preclinical	Unknown Approved Use Unknown

PubMed

Title	Date	PubMed
Simultaneous determination of four antipsychotic drugs in plasma by high-performance liquid chromatography. Application to management of acute intoxications.	2003 Oct 5	14522030
Atypical properties of several classes of antipsychotic drugs on the basis of differential induction of Fos-like immunoreactivity in the rat brain.	2004 Nov 26	15519367
[Hebephrenic schizophrenia].	2005 Oct	16673701

Patents

Sample Use Guides

In Vivo Use Guide

Doses varied from 50 to 400 mg per day

Route of Administration: Oral

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:13:44 UTC 2023` Edited by `admin` on `Fri Dec 15 16:13:44 UTC 2023`
Record UNII	8AFK6F91EQ
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

CARPIPRAMINE

Official Name

English

BAY B 4343 B

Code

English

CARPIPRAMINE [MI]

Common Name

English

Carpipramine [WHO-DD]

Common Name

English

CARBADIPIMIDINE

Common Name

English

1'-(3-(10,11-DIHYDRO-5H-DIBENZ(B,F)AZEPIN-5-YL)PROPYL)-(1,4'-BIPIPERIDINE)-4'-CARBOXAMIDE

Systematic Name

English

carpipramine [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C265