BMS-767778

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C19H20Cl2N4O2
Molecular Weight	407.294
Optical Activity	UNSPECIFIED
Additional Stereochemistry	Yes
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0
Stereo Comments	AXIAL, S

SHOW SMILES / InChI

Structure Search

SMILES

CN(C)C(=O)CN1CC2=C(C1=O)C(C3=CC=C(Cl)C=C3Cl)=C(CN)C(C)=N2

InChI

InChIKey=PECDPZCIECMGCM-UHFFFAOYSA-N

InChI=1S/C19H20Cl2N4O2/c1-10-13(7-22)17(12-5-4-11(20)6-14(12)21)18-15(23-10)8-25(19(18)27)9-16(26)24(2)3/h4-6H,7-9,22H2,1-3H3

HIDE SMILES / InChI

Molecular Formula	C19H20Cl2N4O2
Molecular Weight	407.294
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Substance Class	Chemical Created by `admin` on `Sat Dec 16 11:52:12 UTC 2023` Edited by `admin` on `Sat Dec 16 11:52:12 UTC 2023`
Record UNII	89FYR7JU5A
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

BMS-767778

Common Name

English

6H-PYRROLO(3,4-B)PYRIDINE-6-ACETAMIDE, 3-(AMINOMETHYL)-4-(2,4-DICHLOROPHENYL)-5,7-DIHYDRO-N,N,2-TRIMETHYL-5-OXO-, (4S)-

Systematic Name

English

2-(3-(AMINOMETHYL)-4-(2,4-DICHLOROPHENYL)-2-METHYL-5-OXO-7H-PYRROLO(3,4-B)PYRIDIN-6-YL)-N,N-DIMETHYL-ACETAMIDE

Systematic Name

English

Code System Code Type Description

PUBCHEM

15950755

Created by admin on Sat Dec 16 11:52:12 UTC 2023 , Edited by admin on Sat Dec 16 11:52:12 UTC 2023

PRIMARY

FDA UNII

89FYR7JU5A

Created by admin on Sat Dec 16 11:52:12 UTC 2023 , Edited by admin on Sat Dec 16 11:52:12 UTC 2023

PRIMARY

CAS

915729-95-2

Created by admin on Sat Dec 16 11:52:12 UTC 2023 , Edited by admin on Sat Dec 16 11:52:12 UTC 2023

PRIMARY

Related Record Type Details


					RIGEZF4K05

DIPEPTIDYL PEPTIDASE 4 MEMBRANE FORM

TARGET -> INHIBITOR

Qualification:

IC50

Amount:

Related Record Type Details


					89FYR7JU5A

BMS-767778

ACTIVE MOIETY

Comments:

Official Title: Randomized, Double-Blind, Placebo-Controlled Ascending Single and Multiple Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of BMS-767778 in Healthy Subjects and Subjects With Type 2 Diabetes Mellitus Purpose: To assess the safety and tolerability and the PK/PD relationship of BMS-767778 administered as single and multiple oral doses in healthy subjects, and in subjects with T2DM