Details
Stereochemistry | ACHIRAL |
Molecular Formula | C5H9NO3 |
Molecular Weight | 131.1299 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
NCC(=O)CCC(O)=O
InChI
InChIKey=ZGXJTSGNIOSYLO-UHFFFAOYSA-N
InChI=1S/C5H9NO3/c6-3-4(7)1-2-5(8)9/h1-3,6H2,(H,8,9)
Molecular Formula | C5H9NO3 |
Molecular Weight | 131.1299 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Aminolevulinic Acid is the first compound in the porphyrin synthesis pathway. The metabolism of aminolevulinic acid (ALA) is the first step in the biochemical
pathway resulting in heme synthesis. Aminolevulinic acid is not a photosensitizer, but rather a
metabolic precursor of protoporphyrin IX (PpIX), which is a photosensitizer. The synthesis of ALA is
normally tightly controlled by feedback inhibition of the enzyme, ALA synthetase, presumably by
intracellular heme levels. ALA, when provided to the cell, bypasses this control point and results in the
accumulation of PpIX, which is converted into heme by ferrochelatase through the addition of iron to the PpIX nucleus. Marketed under the brand name LEVULAN KERASTICK for Topical Solution plus blue light illumination using the BLU-U Blue Light Photodynamic Therapy Illuminator, it is indicated for the treatment of minimally to moderately
thick actinic keratoses (Grade 1 or 2, see table 2 for definition) of the face or scalp. Aminolevulinic acid is also being studied in the treatment of other conditions and types of cancer. An orally-administered in vivo diagnostic agent, Aminolevulinic acid, is used in photodynamic diagnosis
(PDD) whose aim is to help doctors visualize the tumor tissue during surgical resection of malignant glioma, it is
already sold in over 20 European countries including Germany and the U.K. According to the presumed mechanism of action, photosensitization following application of aminolevulinic acid (ALA) topical solution occurs through the metabolic conversion of ALA to protoporphyrin IX (PpIX), which accumulates in the skin to which aminolevulinic acid has been applied. When exposed to light of appropriate wavelength and energy, the accumulated PpIX produces a photodynamic reaction, a cytotoxic process dependent upon the simultaneous presence of light and oxygen. The absorption of light results in an excited state of the porphyrin molecule, and subsequent spin transfer from PpIX to molecular oxygen generates singlet oxygen, which can further react to form superoxide and hydroxyl radicals. Photosensitization of actinic (solar) keratosis lesions using aminolevulinic acid, plus illumination with the BLU-UTM Blue Light Photodynamic Therapy Illuminator (BLU-U), is the basis for aminolevulinic acid photodynamic therapy (PDT).
CNS Activity
Sources: https://www.ncbi.nlm.nih.gov/pubmed/12493610 | https://www.ncbi.nlm.nih.gov/pubmed/9792218
Curator's Comment: There is low permeability of the undisrupted BBB in humans
Originator
Sources: http://www.mdpi.com/1420-3049/16/5/4140
Curator's Comment: The first report on excessive protoporphyrin accumulation and high photosensitivity after exogenous administration of ALA in humans was presented by Berlin et al. in 1956
Approval Year
Targets
Primary Target | Pharmacology | Condition | Potency |
---|---|---|---|
Target ID: CHEMBL2311221 |
Conditions
Condition | Modality | Targets | Highest Phase | Product |
---|---|---|---|---|
Primary | LEVULAN KERASTICK Approved UseThe LEVULAN KERASTICK for Topical Solution plus blue light illumination using the BLU-U Blue
Light Photodynamic Therapy Illuminator is indicated for the treatment of minimally to moderately
thick actinic keratoses (Grade 1 or 2, see table 2 for definition) of the face or scalp. Launch Date1999 |
|||
Diagnostic | Gliolan Approved UseGliolan is indicated in adult patients for visualisation of malignant tissue during surgery for malignant
glioma (WHO grade III and IV). Launch Date2006 |
|||
Primary | ALA Approved UseCondylomata Acuminata Launch Date2007 |
Cmax
Value | Dose | Co-administered | Analyte | Population |
---|---|---|---|---|
15.44 μg/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/11961050/ |
100 mg single, intravenous dose: 100 mg route of administration: Intravenous experiment type: SINGLE co-administered: |
AMINOLEVULINIC ACID plasma | Homo sapiens population: HEALTHY age: ADULT sex: UNKNOWN food status: UNKNOWN |
|
4.65 μg/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/11961050/ |
100 mg single, oral dose: 100 mg route of administration: Oral experiment type: SINGLE co-administered: |
AMINOLEVULINIC ACID plasma | Homo sapiens population: HEALTHY age: ADULT sex: UNKNOWN food status: UNKNOWN |
|
274.7 μg/L |
0.2 mg/kg bw single, oral dose: 0.2 mg/kg bw route of administration: Oral experiment type: SINGLE co-administered: |
AMINOLEVULINIC ACID plasma | Homo sapiens population: HEALTHY age: ADULT sex: UNKNOWN food status: UNKNOWN |
|
1862.6 μg/L |
2 mg/kg bw single, oral dose: 2 mg/kg bw route of administration: Oral experiment type: SINGLE co-administered: |
AMINOLEVULINIC ACID plasma | Homo sapiens population: HEALTHY age: ADULT sex: UNKNOWN food status: UNKNOWN |
|
8239.1 μg/L |
20 mg/kg bw single, oral dose: 20 mg/kg bw route of administration: Oral experiment type: SINGLE co-administered: |
AMINOLEVULINIC ACID plasma | Homo sapiens population: HEALTHY age: ADULT sex: UNKNOWN food status: UNKNOWN |
AUC
Value | Dose | Co-administered | Analyte | Population |
---|---|---|---|---|
13.7 μg × h/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/11961050/ |
100 mg single, intravenous dose: 100 mg route of administration: Intravenous experiment type: SINGLE co-administered: |
AMINOLEVULINIC ACID plasma | Homo sapiens population: HEALTHY age: ADULT sex: UNKNOWN food status: UNKNOWN |
|
7.4 μg × h/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/11961050/ |
100 mg single, oral dose: 100 mg route of administration: Oral experiment type: SINGLE co-administered: |
AMINOLEVULINIC ACID plasma | Homo sapiens population: HEALTHY age: ADULT sex: UNKNOWN food status: UNKNOWN |
|
424.2 μg × h/L |
0.2 mg/kg bw single, oral dose: 0.2 mg/kg bw route of administration: Oral experiment type: SINGLE co-administered: |
AMINOLEVULINIC ACID plasma | Homo sapiens population: HEALTHY age: ADULT sex: UNKNOWN food status: UNKNOWN |
|
2901.3 μg × h/L |
2 mg/kg bw single, oral dose: 2 mg/kg bw route of administration: Oral experiment type: SINGLE co-administered: |
AMINOLEVULINIC ACID plasma | Homo sapiens population: HEALTHY age: ADULT sex: UNKNOWN food status: UNKNOWN |
|
27143.5 μg × h/L |
20 mg/kg bw single, oral dose: 20 mg/kg bw route of administration: Oral experiment type: SINGLE co-administered: |
AMINOLEVULINIC ACID plasma | Homo sapiens population: HEALTHY age: ADULT sex: UNKNOWN food status: UNKNOWN |
T1/2
Value | Dose | Co-administered | Analyte | Population |
---|---|---|---|---|
50.1 min EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/11961050/ |
100 mg single, intravenous dose: 100 mg route of administration: Intravenous experiment type: SINGLE co-administered: |
AMINOLEVULINIC ACID plasma | Homo sapiens population: HEALTHY age: ADULT sex: UNKNOWN food status: UNKNOWN |
|
44.4 min EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/11961050/ |
100 mg single, oral dose: 100 mg route of administration: Oral experiment type: SINGLE co-administered: |
AMINOLEVULINIC ACID plasma | Homo sapiens population: HEALTHY age: ADULT sex: UNKNOWN food status: UNKNOWN |
|
0.75 h |
0.2 mg/kg bw single, oral dose: 0.2 mg/kg bw route of administration: Oral experiment type: SINGLE co-administered: |
AMINOLEVULINIC ACID plasma | Homo sapiens population: HEALTHY age: ADULT sex: UNKNOWN food status: UNKNOWN |
|
0.84 h |
2 mg/kg bw single, oral dose: 2 mg/kg bw route of administration: Oral experiment type: SINGLE co-administered: |
AMINOLEVULINIC ACID plasma | Homo sapiens population: HEALTHY age: ADULT sex: UNKNOWN food status: UNKNOWN |
|
1.94 h |
20 mg/kg bw single, oral dose: 20 mg/kg bw route of administration: Oral experiment type: SINGLE co-administered: |
AMINOLEVULINIC ACID plasma | Homo sapiens population: HEALTHY age: ADULT sex: UNKNOWN food status: UNKNOWN |
Funbound
Value | Dose | Co-administered | Analyte | Population |
---|---|---|---|---|
88% |
0.2 mg/kg bw single, oral dose: 0.2 mg/kg bw route of administration: Oral experiment type: SINGLE co-administered: |
AMINOLEVULINIC ACID plasma | Homo sapiens population: HEALTHY age: ADULT sex: UNKNOWN food status: UNKNOWN |
|
88% |
2 mg/kg bw single, oral dose: 2 mg/kg bw route of administration: Oral experiment type: SINGLE co-administered: |
AMINOLEVULINIC ACID plasma | Homo sapiens population: HEALTHY age: ADULT sex: UNKNOWN food status: UNKNOWN |
|
88% |
20 mg/kg bw single, oral dose: 20 mg/kg bw route of administration: Oral experiment type: SINGLE co-administered: |
AMINOLEVULINIC ACID plasma | Homo sapiens population: HEALTHY age: ADULT sex: UNKNOWN food status: UNKNOWN |
Doses
Dose | Population | Adverse events |
---|---|---|
20 mg/kg single, oral Recommended Dose: 20 mg/kg Route: oral Route: single Dose: 20 mg/kg Sources: |
unhealthy, 70.5 years (range: 53–84 years) Health Status: unhealthy Age Group: 70.5 years (range: 53–84 years) Sex: M+F Sources: |
Other AEs: Alanine aminotransferase increase, Hypotension... Other AEs: Alanine aminotransferase increase (grade 3, 6.6%) Sources: Hypotension (grade 3, 1.6%) Urticaria (grade 3, 1.6%) |
10 % 1 times / day multiple, topical Recommended Dose: 10 %, 1 times / day Route: topical Route: multiple Dose: 10 %, 1 times / day Sources: |
unhealthy Health Status: unhealthy Sex: M+F Sources: |
Disc. AE: Application site burning, Application site pain... AEs leading to discontinuation/dose reduction: Application site burning (1 patient) Sources: Application site pain (1 patient) |
100 mg single, intravenous Dose: 100 mg Route: intravenous Route: single Dose: 100 mg Sources: |
healthy |
|
100 mg single, oral |
healthy |
|
1328 mg single, intravesical Dose: 1328 mg Route: intravesical Route: single Dose: 1328 mg Sources: |
unhealthy |
AEs
AE | Significance | Dose | Population |
---|---|---|---|
Hypotension | grade 3, 1.6% | 20 mg/kg single, oral Recommended Dose: 20 mg/kg Route: oral Route: single Dose: 20 mg/kg Sources: |
unhealthy, 70.5 years (range: 53–84 years) Health Status: unhealthy Age Group: 70.5 years (range: 53–84 years) Sex: M+F Sources: |
Urticaria | grade 3, 1.6% | 20 mg/kg single, oral Recommended Dose: 20 mg/kg Route: oral Route: single Dose: 20 mg/kg Sources: |
unhealthy, 70.5 years (range: 53–84 years) Health Status: unhealthy Age Group: 70.5 years (range: 53–84 years) Sex: M+F Sources: |
Alanine aminotransferase increase | grade 3, 6.6% | 20 mg/kg single, oral Recommended Dose: 20 mg/kg Route: oral Route: single Dose: 20 mg/kg Sources: |
unhealthy, 70.5 years (range: 53–84 years) Health Status: unhealthy Age Group: 70.5 years (range: 53–84 years) Sex: M+F Sources: |
Application site burning | 1 patient Disc. AE |
10 % 1 times / day multiple, topical Recommended Dose: 10 %, 1 times / day Route: topical Route: multiple Dose: 10 %, 1 times / day Sources: |
unhealthy Health Status: unhealthy Sex: M+F Sources: |
Application site pain | 1 patient Disc. AE |
10 % 1 times / day multiple, topical Recommended Dose: 10 %, 1 times / day Route: topical Route: multiple Dose: 10 %, 1 times / day Sources: |
unhealthy Health Status: unhealthy Sex: M+F Sources: |
PubMed
Title | Date | PubMed |
---|---|---|
An affordable, portable fluorescence imaging device for skin lesion detection using a dual wavelength approach for image contrast enhancement and aminolaevulinic acid-induced protoporphyrin IX. Part II. In vivo testing. | 2001 |
|
An affordable, portable fluorescence imaging device for skin lesion detection using a dual wavelength approach for image contrast enhancement and aminolaevulinic acid-induced protoporphyrin IX. Part I. Design, spectral and spatial characteristics. | 2001 |
|
Modulator of heme biosynthesis induces apoptosis in leukemia cells. | 2001 Apr |
|
The porphyrias: genetic and acquired aspects. | 2001 Apr |
|
Fluorescence staining of oral cancer using a topical application of 5-aminolevulinic acid: fluorescence microscopic studies. | 2001 Apr |
|
Photodynamic therapy of feline superficial squamous cell carcinoma using topical 5-aminolaevulinic acid. | 2001 Apr |
|
Spectrophotometric microassay for delta-aminolevulinate dehydratase in dried-blood spots as confirmation for hereditary tyrosinemia type I. | 2001 Aug |
|
Correlation between lead exposure indicators and sister chromatid exchange (SCE) frequencies in lymphocytes from inorganic lead exposed workers. | 2001 Aug |
|
Peripheral neuropathy in chronic occupational inorganic lead exposure: a clinical and electrophysiological study. | 2001 Aug |
|
Recognition and transport characteristics of nonpeptidic compounds by basolateral peptide transporter in Caco-2 cells. | 2001 Aug |
|
Anticarcinogenic actions of melatonin which involve antioxidative processes: comparison with other antioxidants. | 2001 Aug |
|
Antitumor effect of 5-aminolevulinic acid-mediated photodynamic therapy can be enhanced by the use of a low dose of photofrin in human tumor xenografts. | 2001 Aug 1 |
|
Evaluation of protoporphyrin IX production, phototoxicity and cell death pathway induced by hexylester of 5-aminolevulinic acid in Reh and HPB-ALL cells. | 2001 Aug 10 |
|
Fluorescence spectroscopy of normal mouse skin exposed to 5-aminolaevulinic acid and red light. | 2001 Aug 15 |
|
Photodynamic therapy with topical delta-aminolaevulinic acid for the treatment of plantar warts. | 2001 Aug 15 |
|
In vivo pharmacokinetics of protoporphyrin IX accumulation following intracutaneous injection of 5-aminolevulinic acid. | 2001 Aug 15 |
|
5-Aminolevulinic acid inhibits [3H]muscimol binding to human and rat brain synaptic membranes. | 2001 Feb |
|
Survival of two patients with severe delta-aminolaevulinic acid dehydratase deficiency porphyria. | 2001 Feb |
|
Haem regulation of the mitochondrial import of the Kluyveromyces lactis 5-aminolaevulinate synthase: an organelle approach. | 2001 Jan 15 |
|
The photosensitizing effect of the photoproduct of protoporphyrin IX. | 2001 Jul |
|
5-Aminolaevulinic acid-mediated photodynamic therapy in multidrug resistant leukemia cells. | 2001 Jul |
|
Some articles should just not be published. | 2001 Jul |
|
Photodynamic therapy of actinic keratoses with topical aminolevulinic acid hydrochloride and fluorescent blue light. | 2001 Jul |
|
On the promoting action of tamoxifen in a model of hepatocarcinogenesis induced by p-dimethylaminoazobenzene in CF1 mice. | 2001 Jul |
|
Photosensitization and mechanism of cytotoxicity induced by the use of ALA derivatives in photodynamic therapy. | 2001 Jul 20 |
|
Mechanistic basis for suicide inactivation of porphobilinogen synthase by 4,7-dioxosebacic acid, an inhibitor that shows dramatic species selectivity. | 2001 Jul 27 |
|
Photobiological activity of exogenous and endogenous porphyrin derivatives in Escherichia coli and Enterococcus hirae cells. | 2001 Jun |
|
Effect of photodynamic therapy on urinary bladder function: an experimental study with rats. | 2001 Jun |
|
Topical 5-aminolaevulinic acid photodynamic therapy for tumour-stage mycosis fungoides. | 2001 Jun |
|
Systemic photodynamic therapy with aminolaevulinic acid delays the appearance of ultraviolet-induced skin tumours in mice. | 2001 Jun |
|
Role of 5-aminolevulinic acid in the diagnosis and treatment of superficial bladder cancer: improvement in diagnostic sensitivity. | 2001 Jun |
|
High efficiency of 5-aminolevulinate-photodynamic treatment using UVA irradiation. | 2001 Jun |
|
Evidence for direct interaction between enzyme I(Ntr) and aspartokinase to regulate bacterial oligopeptide transport. | 2001 Jun 15 |
|
[Are new treatments always effective ?]. | 2001 Jun-Jul |
|
Iontophoretic delivery of 5-aminolevulinic acid (ALA): effect of pH. | 2001 Mar |
|
Bowen's disease, solar keratoses and superficial basal cell carcinomas treated by photodynamic therapy using a large-field incoherent light source. | 2001 Mar |
|
Light irradiation increases embryotoxicity of photodynamic therapy sensitizers (5-aminolevulinic acid and protoporphyrin IX) in chick embryos. | 2001 Mar-Apr |
|
Abortive assembly of succinate-ubiquinone reductase (complex II) in a ferrochelatase-deficient mutant of Escherichia coli. | 2001 May |
|
[Fluorescence cytology of the urinary bladder]. | 2001 May |
Patents
Sample Use Guides
In Vivo Use Guide
Curator's Comment: Can also be used orally for visualisation of malignant tissue during surgery for malignant glioma (WHO grade III and IV): the recommended dose is 20 mg 5-ALA HCl per kilogram body weight. http://www.ema.europa.eu/docs/en_GB/document_library/EPAR_-_Product_Information/human/000744/WC500021790.pdf
LEVULAN KERASTICK for Topical Solution 20% (aminolevulinic acid HCl) is intended for direct application to individual
lesions diagnosed as actinic keratoses and not to perilesional skin. This product is not intended for
application by patients or unqualified medical personnel. Application should involve either scalp or
face lesions, but not both simultaneously. The recommended treatment frequency is: one application of
the LEVULAN KERASTICK Topical Solution and one dose of illumination per treatment site per 8
week treatment session. Each individual LEVULAN KERASTICK should be used for only one
patient. Photodynamic therapy for actinic keratoses with LEVULAN KERASTICK for Topical
Solution is a two stage process involving a) application of the product to the target lesions with
LEVULAN KERASTICK Topical Solution, followed 14 to 18 hours later by b) illumination with blue
light using the BLU-U Blue Light Photodynamic Therapy Illuminator. The second visit, for
illumination, must take place in the 14-18 hour window following application.
Route of Administration:
Topical
In Vitro Use Guide
Sources: https://www.ncbi.nlm.nih.gov/pubmed/27764515
Curator's Comment: Glioma cells, seeded at the bottom of 96-well plates and incubated with ALA (10 ug/ml) for 6 h, were exposed to the sinusoidal US pulses with a resonance frequency of 1 MHz, 1000 µs duration, 0.4 duty-cycle, and average acoustic power varying from 2 W to 6 W. Ultrasound waves were generated by a flat circular piezoelectric transducer with a diameter of 25 mm. Cell viability was determined by MTT assay.
Aminolevulinic acid (10 ug/ml) mediated sonosensitization of rat RG2 glioma cells in vitro. ALA-mediated SDT evokes cytotoxic effects of low intensity US on rat RG2 glioma cells in vitro.
Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 18:07:10 GMT 2025
by
admin
on
Mon Mar 31 18:07:10 GMT 2025
|
Record UNII |
88755TAZ87
|
Record Status |
Validated (UNII)
|
Record Version |
|
-
Download
Name | Type | Language | ||
---|---|---|---|---|
|
Preferred Name | English | ||
|
Systematic Name | English | ||
|
Common Name | English | ||
|
Systematic Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Systematic Name | English | ||
|
Common Name | English | ||
|
Systematic Name | English | ||
|
Common Name | English | ||
|
Systematic Name | English | ||
|
Systematic Name | English |
Classification Tree | Code System | Code | ||
---|---|---|---|---|
|
NDF-RT |
N0000175846
Created by
admin on Mon Mar 31 18:07:10 GMT 2025 , Edited by admin on Mon Mar 31 18:07:10 GMT 2025
|
||
|
FDA ORPHAN DRUG |
387312
Created by
admin on Mon Mar 31 18:07:10 GMT 2025 , Edited by admin on Mon Mar 31 18:07:10 GMT 2025
|
||
|
FDA ORPHAN DRUG |
710519
Created by
admin on Mon Mar 31 18:07:10 GMT 2025 , Edited by admin on Mon Mar 31 18:07:10 GMT 2025
|
||
|
WHO-ATC |
L01XD04
Created by
admin on Mon Mar 31 18:07:10 GMT 2025 , Edited by admin on Mon Mar 31 18:07:10 GMT 2025
|
||
|
NDF-RT |
N0000171207
Created by
admin on Mon Mar 31 18:07:10 GMT 2025 , Edited by admin on Mon Mar 31 18:07:10 GMT 2025
|
||
|
CFR |
21 CFR 862.1060
Created by
admin on Mon Mar 31 18:07:10 GMT 2025 , Edited by admin on Mon Mar 31 18:07:10 GMT 2025
|
||
|
NCI_THESAURUS |
C1420
Created by
admin on Mon Mar 31 18:07:10 GMT 2025 , Edited by admin on Mon Mar 31 18:07:10 GMT 2025
|
||
|
WHO-VATC |
QL01XD04
Created by
admin on Mon Mar 31 18:07:10 GMT 2025 , Edited by admin on Mon Mar 31 18:07:10 GMT 2025
|
||
|
NDF-RT |
N0000171207
Created by
admin on Mon Mar 31 18:07:10 GMT 2025 , Edited by admin on Mon Mar 31 18:07:10 GMT 2025
|
||
|
NDF-RT |
N0000171207
Created by
admin on Mon Mar 31 18:07:10 GMT 2025 , Edited by admin on Mon Mar 31 18:07:10 GMT 2025
|
||
|
FDA ORPHAN DRUG |
811521
Created by
admin on Mon Mar 31 18:07:10 GMT 2025 , Edited by admin on Mon Mar 31 18:07:10 GMT 2025
|
||
|
NDF-RT |
N0000171207
Created by
admin on Mon Mar 31 18:07:10 GMT 2025 , Edited by admin on Mon Mar 31 18:07:10 GMT 2025
|
||
|
EU-Orphan Drug |
EU/3/16/1811
Created by
admin on Mon Mar 31 18:07:10 GMT 2025 , Edited by admin on Mon Mar 31 18:07:10 GMT 2025
|
Code System | Code | Type | Description | ||
---|---|---|---|---|---|
|
88755TAZ87
Created by
admin on Mon Mar 31 18:07:10 GMT 2025 , Edited by admin on Mon Mar 31 18:07:10 GMT 2025
|
PRIMARY | |||
|
17549
Created by
admin on Mon Mar 31 18:07:10 GMT 2025 , Edited by admin on Mon Mar 31 18:07:10 GMT 2025
|
PRIMARY | |||
|
137
Created by
admin on Mon Mar 31 18:07:10 GMT 2025 , Edited by admin on Mon Mar 31 18:07:10 GMT 2025
|
PRIMARY | |||
|
D000622
Created by
admin on Mon Mar 31 18:07:10 GMT 2025 , Edited by admin on Mon Mar 31 18:07:10 GMT 2025
|
PRIMARY | |||
|
AMINOLEVULINIC ACID
Created by
admin on Mon Mar 31 18:07:10 GMT 2025 , Edited by admin on Mon Mar 31 18:07:10 GMT 2025
|
PRIMARY | |||
|
4784
Created by
admin on Mon Mar 31 18:07:10 GMT 2025 , Edited by admin on Mon Mar 31 18:07:10 GMT 2025
|
PRIMARY | |||
|
88755TAZ87
Created by
admin on Mon Mar 31 18:07:10 GMT 2025 , Edited by admin on Mon Mar 31 18:07:10 GMT 2025
|
PRIMARY | |||
|
DTXSID8048490
Created by
admin on Mon Mar 31 18:07:10 GMT 2025 , Edited by admin on Mon Mar 31 18:07:10 GMT 2025
|
PRIMARY | |||
|
100000089317
Created by
admin on Mon Mar 31 18:07:10 GMT 2025 , Edited by admin on Mon Mar 31 18:07:10 GMT 2025
|
PRIMARY | |||
|
C234
Created by
admin on Mon Mar 31 18:07:10 GMT 2025 , Edited by admin on Mon Mar 31 18:07:10 GMT 2025
|
PRIMARY | |||
|
m1713
Created by
admin on Mon Mar 31 18:07:10 GMT 2025 , Edited by admin on Mon Mar 31 18:07:10 GMT 2025
|
PRIMARY | Merck Index | ||
|
SUB12853MIG
Created by
admin on Mon Mar 31 18:07:10 GMT 2025 , Edited by admin on Mon Mar 31 18:07:10 GMT 2025
|
PRIMARY | |||
|
106-60-5
Created by
admin on Mon Mar 31 18:07:10 GMT 2025 , Edited by admin on Mon Mar 31 18:07:10 GMT 2025
|
PRIMARY | |||
|
DB00855
Created by
admin on Mon Mar 31 18:07:10 GMT 2025 , Edited by admin on Mon Mar 31 18:07:10 GMT 2025
|
PRIMARY | |||
|
166
Created by
admin on Mon Mar 31 18:07:10 GMT 2025 , Edited by admin on Mon Mar 31 18:07:10 GMT 2025
|
PRIMARY | |||
|
683
Created by
admin on Mon Mar 31 18:07:10 GMT 2025 , Edited by admin on Mon Mar 31 18:07:10 GMT 2025
|
PRIMARY | |||
|
155002
Created by
admin on Mon Mar 31 18:07:10 GMT 2025 , Edited by admin on Mon Mar 31 18:07:10 GMT 2025
|
ALTERNATIVE | |||
|
203-414-1
Created by
admin on Mon Mar 31 18:07:10 GMT 2025 , Edited by admin on Mon Mar 31 18:07:10 GMT 2025
|
PRIMARY |
Related Record | Type | Details | ||
---|---|---|---|---|
|
SALT/SOLVATE -> PARENT |
|
||
|
SALT/SOLVATE -> PARENT |
|
Related Record | Type | Details | ||
---|---|---|---|---|
|
PARENT -> IMPURITY |
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
|
||
|
IMPURITY -> PARENT |
|
Related Record | Type | Details | ||
---|---|---|---|---|
|
ACTIVE MOIETY |
|