5-VINYLDEOXYURIDINE

OC[C@H]1O[C@H](C[C@@H]1O)N2C=C(C=C)C(=O)NC2=O

InChIKey=YAAQOXBNCODRSI-DJLDLDEBSA-N

InChI=1S/C11H14N2O5/c1-2-6-4-13(11(17)12-10(6)16)9-3-7(15)8(5-14)18-9/h2,4,7-9,14-15H,1,3,5H2,(H,12,16,17)/t7-,8+,9+/m0/s1

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	3 / 3
E/Z Centers	0
Optical Activity	UNSPECIFIED

PubMed

Title	Date	PubMed
Synthesis and in vitro anti-mycobacterial activity of 5-substituted pyrimidine nucleosides.	2005-12-15	16140016
Synthesis and biological investigations of 5-substituted pyrimidine nucleosides coupled to a dihydropyridine/pyridinium salt redox chemical delivery system.	2001-11	11822172
Vaccinia virus inhibitors as a paradigm for the chemotherapy of poxvirus infections.	2001-04	11292644
Structure-activity relationship of the affinity of 5-substituted uracil nucleoside analogues for varicella-zoster virus thymidine kinase and their activity against varicella-zoster virus.	1997-08	9298756
Synthesis and antiviral activity of phosphonoacetic and phosphonoformic acid esters of 5-bromo-2'-deoxyuridine and related pyrimidine nucleosides and acyclonucleosides.	1989-02	2521518
5-substituted deoxyuridines--structural requirements for antiviral activity against herpes simplex virus types 1 and 2 and possible biochemical basis for relative potency.	1984-06	6089658
Antiherpes activity of (E)-5-(2-bromovinyl)- and 5-vinyl-1-beta-D-arabinofuranosyluracil and some other 5-substituted uracil arabinosyl nucleosides in two different cell lines.	1983-09	6316849
(E)-5-(2-Bromovinyl)-2'-deoxyuridine: a potent and selective anti-herpes agent.	1979-06	223163
Antiviral action and cellular toxicity of four thymidine analogues: 5-ethyl-,5-vinyl-, 5-propyl-, and 5-allyl-2'- deoxyuridine.	1976-07	185944

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 22:09:38 GMT 2025` Edited by `admin` on `Mon Mar 31 22:09:38 GMT 2025`
Record UNII	87V72AT994
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

5-VINYLDEOXYURIDINE

Systematic Name

English

5-VINYL-2'-DEOXYURIDINE

Preferred Name

English

Code System Code Type Description

PUBCHEM

148744

Created by admin on Mon Mar 31 22:09:38 GMT 2025 , Edited by admin on Mon Mar 31 22:09:38 GMT 2025

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EPA CompTox

DTXSID10970866

Created by admin on Mon Mar 31 22:09:38 GMT 2025 , Edited by admin on Mon Mar 31 22:09:38 GMT 2025

PRIMARY

FDA UNII

87V72AT994

Created by admin on Mon Mar 31 22:09:38 GMT 2025 , Edited by admin on Mon Mar 31 22:09:38 GMT 2025

PRIMARY

CAS

55520-67-7

Created by admin on Mon Mar 31 22:09:38 GMT 2025 , Edited by admin on Mon Mar 31 22:09:38 GMT 2025

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Related Record Type Details


					87V72AT994

ACTIVE MOIETY