NORIBOGAINE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C19H24N2O
Molecular Weight	296.4067
Optical Activity	UNSPECIFIED
Defined Stereocenters	4 / 4
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC[C@H]1C[C@H]2C[C@@H]3[C@H]1N(C2)CCC4=C3NC5=C4C=C(O)C=C5

InChI

InChIKey=RAUCDOKTMDOIPF-ZFRACTKTSA-N

InChI=1S/C19H24N2O/c1-2-12-7-11-8-16-18-14(5-6-21(10-11)19(12)16)15-9-13(22)3-4-17(15)20-18/h3-4,9,11-12,16,19-20,22H,2,5-8,10H2,1H3/t11-,12-,16-,19-/m0/s1

HIDE SMILES / InChI

Molecular Formula	C19H24N2O
Molecular Weight	296.4067
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	4 / 4
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

PubMed

Title	Date	PubMed
Noribogaine, but not 18-MC, exhibits similar actions as ibogaine on GDNF expression and ethanol self-administration.	2010-10	21040239
Indolealkylamines: biotransformations and potential drug-drug interactions.	2008-06	18454322
Determination of ibogaine and noribogaine in biological fluids and hair by LC-MS/MS after Tabernanthe iboga abuse Iboga alkaloids distribution in a drowning death case.	2008-03-21	18024037
Ibogaine, an anti-addictive drug: pharmacology and time to go further in development. A narrative review.	2008-03	18650249
Acute toxicity of ibogaine and noribogaine.	2008	19142057
Liquid chromatography-electrospray mass spectrometry determination of ibogaine and noribogaine in human plasma and whole blood. Application to a poisoning involving Tabernanthe iboga root.	2006-11-07	16798116
Distribution of ibogaine and noribogaine in a man following a poisoning involving root bark of the Tabernanthe iboga shrub.	2006-09	16959135
Quantitation of ibogaine and 12-hydroxyibogamine in human plasma by liquid chromatography with fluorimetric detection.	2005-08-05	16002351
Addiction research. Ibogaine therapy: a 'vast, uncontrolled experiment'.	2005-04-15	15831735
In vivo neurobiological effects of ibogaine and its O-desmethyl metabolite, 12-hydroxyibogamine (noribogaine), in rats.	2001-05	11303040
Comparative neuropharmacology of ibogaine and its O-desmethyl metabolite, noribogaine.	2001	11705118
Mechanisms of antiaddictive actions of ibogaine.	1998-05-30	9668680
Time-dependent interactions between iboga agents and cocaine.	1997-10-08	9384223

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 21:55:01 GMT 2025` Edited by `admin` on `Mon Mar 31 21:55:01 GMT 2025`
Record UNII	87T5QTN9SK
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

J666.099A

Preferred Name

English

NORIBOGAINE

Common Name

English

IBOGAINE, O-DEMETHYL-

Common Name

English

O-NORIBOGAINE

Common Name

English

IBOGAMIN-12-OL

Common Name

English

(-)-NORIBOGAINE

Common Name

English

12-HYDROXYIBOGAMINE

Common Name

English

O-DEMETHYLIBOGAINE

Common Name

English

Code System Code Type Description

EVMPD

SUB79173