BMS-645737

CC(C)C1=C2N(C=C1C3=NN=C(C)O3)N=CN=C2NC4=CN=C5NC(C)=CC5=C4

InChIKey=OOQXPATWSOGSAV-UHFFFAOYSA-N

InChI=1S/C20H20N8O/c1-10(2)16-15(20-27-26-12(4)29-20)8-28-17(16)19(22-9-23-28)25-14-6-13-5-11(3)24-18(13)21-7-14/h5-10H,1-4H3,(H,21,24)(H,22,23,25)

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

PubMed

Title	Date	PubMed
Incisor degeneration in rats induced by vascular endothelial growth factor/fibroblast growth factor receptor tyrosine kinase inhibition.	2010-02	20100840
Metabolism of 5-isopropyl-6-(5-methyl-1,3,4-oxadiazol-2-yl)-N-(2-methyl-1H-pyrrolo[2,3-b]pyridin-5-yl)pyrrolo[2,1-f][1,2,4]triazin-4-amine (BMS-645737): identification of an unusual N-acetylglucosamine conjugate in the cynomolgus monkey.	2008-12	18787055
Discovery and preclinical studies of 5-isopropyl-6-(5-methyl-1,3,4-oxadiazol-2-yl)-N-(2-methyl-1H-pyrrolo[2,3-b]pyridin-5-yl)pyrrolo[2,1-f][1,2,4]triazin-4-amine (BMS-645737), an in vivo active potent VEGFR-2 inhibitor.	2008-05-01	18395443

Substance Class	Chemical Created by `admin` on `Mon Mar 31 22:38:24 GMT 2025` Edited by `admin` on `Mon Mar 31 22:38:24 GMT 2025`
Record UNII	86H6HFH34L
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

BMS-645737

Common Name

English

PYRROLO(2,1-F)(1,2,4)TRIAZIN-4-AMINE, 5-(1-METHYLETHYL)-6-(5-METHYL-1,3,4-OXADIAZOL-2-YL)-N-(2-METHYL-1H-PYRROLO(2,3-B)PYRIDIN-5-YL)-

Preferred Name

English

Code System Code Type Description

PUBCHEM

22273644

Created by admin on Mon Mar 31 22:38:24 GMT 2025 , Edited by admin on Mon Mar 31 22:38:24 GMT 2025

PRIMARY

EPA CompTox

DTXSID30215483

Created by admin on Mon Mar 31 22:38:24 GMT 2025 , Edited by admin on Mon Mar 31 22:38:24 GMT 2025

PRIMARY

CAS

651744-16-0

Created by admin on Mon Mar 31 22:38:24 GMT 2025 , Edited by admin on Mon Mar 31 22:38:24 GMT 2025

PRIMARY

FDA UNII

86H6HFH34L

Created by admin on Mon Mar 31 22:38:24 GMT 2025 , Edited by admin on Mon Mar 31 22:38:24 GMT 2025

PRIMARY

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					86H6HFH34L

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