PIMEFYLLINE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C15H18N6O2
Molecular Weight	314.3424
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of PIMEFYLLINE

Structure Search

SMILES

CN1C2=C(N(CCNCC3=CN=CC=C3)C=N2)C(=O)N(C)C1=O

InChI

InChIKey=CDHVRXOLGDSJGX-UHFFFAOYSA-N

InChI=1S/C15H18N6O2/c1-19-13-12(14(22)20(2)15(19)23)21(10-18-13)7-6-17-9-11-4-3-5-16-8-11/h3-5,8,10,17H,6-7,9H2,1-2H3

HIDE SMILES / InChI

Molecular Formula	C15H18N6O2
Molecular Weight	314.3424
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.drugfuture.com/chemdata/Pimefylline.html | https://apps.who.int/iris/bitstream/handle/10665/67830/WHO_EDM_QSM_2003.2.pdf | Elks, J. (2014) The Dictionary of Drugs: Chemical Data, page 981, retrieved from: https://books.google.ru/books?id=0vXTBwAAQBAJ

Pimefylline is an N-methylated xanthine derivative. It is a coronary vasodilator and muscle relaxant.

Approval Year

PubMed

PubMed

Title	Date	PubMed
[Hemokinetic and metabolic action of 7-2-(3-pyridyl-methylamino)-ethyl-theophylline nicotinate as a basis of medical treatment of chronic obliterating peripheral arteriopathy].	1973-11	4776567

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:27:12 GMT 2025` Edited by `admin` on `Mon Mar 31 18:27:12 GMT 2025`
Record UNII	8680B5Y37A
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

PIMEFYLLINE

Official Name

English

PIMEFYLLINE [MI]

Preferred Name

English

7-(2-((3-PYRIDYLMETHYL)-AMINO)ETHYL)THEOPHYLLINE

Systematic Name

English

pimefylline [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C744

Created by admin on Mon Mar 31 18:27:12 GMT 2025 , Edited by admin on Mon Mar 31 18:27:12 GMT 2025

NCI_THESAURUS

C29707

Created by admin on Mon Mar 31 18:27:12 GMT 2025 , Edited by admin on Mon Mar 31 18:27:12 GMT 2025

Code System Code Type Description

INN

2606

Created by admin on Mon Mar 31 18:27:12 GMT 2025 , Edited by admin on Mon Mar 31 18:27:12 GMT 2025

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CAS

10001-43-1

Created by admin on Mon Mar 31 18:27:12 GMT 2025 , Edited by admin on Mon Mar 31 18:27:12 GMT 2025

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NCI_THESAURUS

C66384

Created by admin on Mon Mar 31 18:27:12 GMT 2025 , Edited by admin on Mon Mar 31 18:27:12 GMT 2025

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DRUG CENTRAL

3472

Created by admin on Mon Mar 31 18:27:12 GMT 2025 , Edited by admin on Mon Mar 31 18:27:12 GMT 2025

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SMS_ID

100000081950

Created by admin on Mon Mar 31 18:27:12 GMT 2025 , Edited by admin on Mon Mar 31 18:27:12 GMT 2025

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EVMPD

SUB09837MIG

Created by admin on Mon Mar 31 18:27:12 GMT 2025 , Edited by admin on Mon Mar 31 18:27:12 GMT 2025

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MERCK INDEX

m8812

Created by admin on Mon Mar 31 18:27:12 GMT 2025 , Edited by admin on Mon Mar 31 18:27:12 GMT 2025

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Merck Index

EPA CompTox

DTXSID30142861

Created by admin on Mon Mar 31 18:27:12 GMT 2025 , Edited by admin on Mon Mar 31 18:27:12 GMT 2025

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ChEMBL

CHEMBL2105195

Created by admin on Mon Mar 31 18:27:12 GMT 2025 , Edited by admin on Mon Mar 31 18:27:12 GMT 2025

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PUBCHEM

65597

Created by admin on Mon Mar 31 18:27:12 GMT 2025 , Edited by admin on Mon Mar 31 18:27:12 GMT 2025

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FDA UNII

8680B5Y37A

Created by admin on Mon Mar 31 18:27:12 GMT 2025 , Edited by admin on Mon Mar 31 18:27:12 GMT 2025

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Related Record Type Details


					8Y694512DA

PIMEPHYLLINE NICOTINATE

SALT/SOLVATE -> PARENT

Related Record Type Details


					8680B5Y37A

ACTIVE MOIETY