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Details

Stereochemistry ACHIRAL
Molecular Formula C13H14N2O2
Molecular Weight 230.2625
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of SORETOLIDE

SMILES

CC1=CC(NC(=O)C2=C(C)C=CC=C2C)=NO1

InChI

InChIKey=GBTKANSDFYFQBK-UHFFFAOYSA-N
InChI=1S/C13H14N2O2/c1-8-5-4-6-9(2)12(8)13(16)14-11-7-10(3)17-15-11/h4-7H,1-3H3,(H,14,15,16)

HIDE SMILES / InChI

Molecular Formula C13H14N2O2
Molecular Weight 230.2625
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Soretolide is an orally active benzamide derivative with anticonvulsant effects and a similar profile of activity to carbamazepine. In animal models, soretolide showed an anticonvulsant profile similar to carbamazepine, being active in the maximal electroshock test and poorly active against pentylenetetrazole-induced seizures. Researchers at the University of Washington, USA and Laboratoires Biocodex, France were investigating the potential use of soretolide as an anticonvulsant. However, development of the compound appears to have been discontinued.

Approval Year

PubMed

PubMed

TitleDatePubMed
Soretolide (Laboratoires Biocodex).
2001 Jun
Substance Class Chemical
Created
by admin
on Sat Dec 16 16:47:04 GMT 2023
Edited
by admin
on Sat Dec 16 16:47:04 GMT 2023
Record UNII
85950PA18Z
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
SORETOLIDE
INN   WHO-DD  
INN  
Official Name English
2,6-DIMETHYL-N-(5-METHYL-3-ISOXAZOLYL)BENZAMIDE
Systematic Name English
soretolide [INN]
Common Name English
Soretolide [WHO-DD]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C264
Created by admin on Sat Dec 16 16:47:04 GMT 2023 , Edited by admin on Sat Dec 16 16:47:04 GMT 2023
Code System Code Type Description
EVMPD
SUB10604MIG
Created by admin on Sat Dec 16 16:47:04 GMT 2023 , Edited by admin on Sat Dec 16 16:47:04 GMT 2023
PRIMARY
CAS
130403-08-6
Created by admin on Sat Dec 16 16:47:04 GMT 2023 , Edited by admin on Sat Dec 16 16:47:04 GMT 2023
PRIMARY
FDA UNII
85950PA18Z
Created by admin on Sat Dec 16 16:47:04 GMT 2023 , Edited by admin on Sat Dec 16 16:47:04 GMT 2023
PRIMARY
PUBCHEM
198730
Created by admin on Sat Dec 16 16:47:04 GMT 2023 , Edited by admin on Sat Dec 16 16:47:04 GMT 2023
PRIMARY
MESH
C105493
Created by admin on Sat Dec 16 16:47:04 GMT 2023 , Edited by admin on Sat Dec 16 16:47:04 GMT 2023
PRIMARY
NCI_THESAURUS
C152408
Created by admin on Sat Dec 16 16:47:04 GMT 2023 , Edited by admin on Sat Dec 16 16:47:04 GMT 2023
PRIMARY
INN
7346
Created by admin on Sat Dec 16 16:47:04 GMT 2023 , Edited by admin on Sat Dec 16 16:47:04 GMT 2023
PRIMARY
ChEMBL
CHEMBL1958077
Created by admin on Sat Dec 16 16:47:04 GMT 2023 , Edited by admin on Sat Dec 16 16:47:04 GMT 2023
PRIMARY
SMS_ID
100000083815
Created by admin on Sat Dec 16 16:47:04 GMT 2023 , Edited by admin on Sat Dec 16 16:47:04 GMT 2023
PRIMARY
EPA CompTox
DTXSID60156517
Created by admin on Sat Dec 16 16:47:04 GMT 2023 , Edited by admin on Sat Dec 16 16:47:04 GMT 2023
PRIMARY
Related Record Type Details
ACTIVE MOIETY