ABT-107 TARTRATE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C19H20N4O.C4H6O6
Molecular Weight	470.4751
Optical Activity	UNSPECIFIED
Defined Stereocenters	3 / 3
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

O[C@H]([C@@H](O)C(O)=O)C(O)=O.C1CN2CCC1[C@H](C2)OC3=CC=C(N=N3)C4=CC=C5NC=CC5=C4

InChI

InChIKey=YESVBFSPCCSJKX-UWPISNKWSA-N

InChI=1S/C19H20N4O.C4H6O6/c1-2-16-15(5-8-20-16)11-14(1)17-3-4-19(22-21-17)24-18-12-23-9-6-13(18)7-10-23;5-1(3(7)8)2(6)4(9)10/h1-5,8,11,13,18,20H,6-7,9-10,12H2;1-2,5-6H,(H,7,8)(H,9,10)/t18-;1-,2-/m01/s1

HIDE SMILES / InChI

Molecular Formula	C19H20N4O
Molecular Weight	320.3883
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	0
Optical Activity	UNSPECIFIED

Molecular Formula	C4H6O6
Molecular Weight	150.0868
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

PubMed

Title	Date	PubMed
In vitro pharmacological characterization of a novel selective alpha7 neuronal nicotinic acetylcholine receptor agonist ABT-107.	2010 Sep 1	20504915
In vivo pharmacological characterization of a novel selective alpha7 neuronal nicotinic acetylcholine receptor agonist ABT-107: preclinical considerations in Alzheimer's disease.	2010 Sep 1	20504913

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:30:23 GMT 2023` Edited by `admin` on `Fri Dec 15 16:30:23 GMT 2023`
Record UNII	83C9062IVH
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ABT-107 TARTRATE

Code

English

(3R)-3-((6-(1H-INDOL-5-YL)PYRIDAZIN-3-YL)OXY)-1-AZONIABICYCLO(2.2.2)OCTANE (2R,3R)-3-CARBOXY-2,3-DIHYDROXYPROPANOATE

Systematic Name

English

1-AZABICYCLO(2.2.2)OCTANE, 3-((6-(1H-INDOL-5-YL)-3-PYRIDAZINYL)OXY)-, (3R)-, (2R,3R)-2,3-DIHYDROXYBUTANEDIOATE (1:1)

Systematic Name

English

BUTANEDIOIC ACID, 2,3-DIHYDROXY-, (2R,3R)-, COMPD. WITH (3R)-3-((6-(1H-INDOL-5-YL)-3-PYRIDAZINYL)OXY)-1-AZABICYCLO(2.2.2)OCTANE (1:1)

Common Name

English

Code System Code Type Description

ChEMBL

CHEMBL2151570

Created by admin on Fri Dec 15 16:30:23 GMT 2023 , Edited by admin on Fri Dec 15 16:30:23 GMT 2023

PRIMARY

PUBCHEM

68540578

Created by admin on Fri Dec 15 16:30:23 GMT 2023 , Edited by admin on Fri Dec 15 16:30:23 GMT 2023

PRIMARY

FDA UNII

83C9062IVH

Created by admin on Fri Dec 15 16:30:23 GMT 2023 , Edited by admin on Fri Dec 15 16:30:23 GMT 2023

PRIMARY

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ABT-107 FREE BASE

ACTIVE MOIETY