COSFROVIXIMAB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Investigational

Approval Year

Substance Class	Protein Created by `admin` on `Tue Apr 01 16:24:42 GMT 2025` Edited by `admin` on `Tue Apr 01 16:24:42 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	MOUSE CHIMERIC
Sequence Type	COMPLETE
Record UNII	820CI2BHRP
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

cosfroviximab [INN]

Preferred Name

English

COSFROVIXIMAB

Official Name

English

IMMUNOGLOBULIN G1-KAPPA, ANTI-(EBOLAVIRUS/RESTON EBOLAVIRUS/SUDAN EBOLAVIRUS/TAI FOREST EBOLAVIRUS GLYCOPROTEIN)CHIMERIC HOMO SAPIENS-MUS MUSCULUS MONOCLONAL ANTIBODY: .GAMMA.1 HEAVY CHAIN (1-452) (MUS MUSCULUS VH (IGHV8-8*01 (77%) (IGHD)-IGHJ4*01 (93%))

Systematic Name

English

ZMAPP COMPONENT C13C6FR1

Common Name

English

13C6

Code

English

C13C6FR1

Code

English

COSFROVIXIMAB [USAN]

Common Name

English

Cosfroviximab [WHO-DD]

Common Name

English

ZMAPP COMPONENT C13C6

Brand Name

English

ZMAPP COMPONENT C13C6-FR1

Common Name

English

C13C6-FR1

Code

English

MB-003 COMPONENT C13C6-FR1

Common Name

English

IMMUNOGLOBULIN G1, ANTI-(EBOLAVIRUS/RESTON EBOLAVIRUS/SUDAN EBOLAVIRUS/TAI FOREST EBOLAVIRUS GLYCOPROTEIN) (HUMAN-MUS MUSCULUS MONOCLONAL C13C6-FR1 HEAVY CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL C13C6-FR1 .KAPPA.-CHAIN, DIMER

Common Name

English

Classification Tree Code System Code

FDA ORPHAN DRUG

440914

Created by admin on Tue Apr 01 16:24:42 GMT 2025 , Edited by admin on Tue Apr 01 16:24:42 GMT 2025

Code System Code Type Description

FDA UNII

820CI2BHRP

Created by admin on Tue Apr 01 16:24:42 GMT 2025 , Edited by admin on Tue Apr 01 16:24:42 GMT 2025

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CAS

1792982-57-0

Created by admin on Tue Apr 01 16:24:42 GMT 2025 , Edited by admin on Tue Apr 01 16:24:42 GMT 2025

PRIMARY

SMS_ID

300000005740

Created by admin on Tue Apr 01 16:24:42 GMT 2025 , Edited by admin on Tue Apr 01 16:24:42 GMT 2025

PRIMARY

NCI_THESAURUS

C171831

Created by admin on Tue Apr 01 16:24:42 GMT 2025 , Edited by admin on Tue Apr 01 16:24:42 GMT 2025

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USAN

DE-19

Created by admin on Tue Apr 01 16:24:42 GMT 2025 , Edited by admin on Tue Apr 01 16:24:42 GMT 2025

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INN

10535

Created by admin on Tue Apr 01 16:24:42 GMT 2025 , Edited by admin on Tue Apr 01 16:24:42 GMT 2025

PRIMARY

From	To
1_22	1_97
1_149	1_205
1_225	3_213
1_231	2_231
1_234	2_234
1_266	1_326
1_372	1_430
2_22	2_97
2_149	2_205
2_225	4_213
2_266	2_326
2_372	2_430
3_23	3_88
3_133	3_193
4_23	4_88
4_133	4_193

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_302
N	2_302

Related Record Type Details


					XH5V2SQ5FI

ZAIRE EBOLAVIRUS STRAIN KIKWIT-95 ENVELOPE GLYCOPROTEIN

TARGET->LIGAND

Amount:


					3R8G5WNW24

ZAIRE EBOLAVIRUS

TARGET ORGANISM->INHIBITOR

Comments:

Does not inhibit virus directly in-vitro. May rely on complement for in-vivo activity.

Amount:

Related Record Type Details


					820CI2BHRP

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL