U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 11:24:20 GMT 2023
Edited
by admin
on Sat Dec 16 11:24:20 GMT 2023
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG1
Sequence Origin MOUSE CHIMERIC
Sequence Type COMPLETE
Record UNII
820CI2BHRP
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
COSFROVIXIMAB
INN   USAN  
USAN   INN  
Official Name English
IMMUNOGLOBULIN G1-KAPPA, ANTI-(EBOLAVIRUS/RESTON EBOLAVIRUS/SUDAN EBOLAVIRUS/TAI FOREST EBOLAVIRUS GLYCOPROTEIN)CHIMERIC HOMO SAPIENS-MUS MUSCULUS MONOCLONAL ANTIBODY: .GAMMA.1 HEAVY CHAIN (1-452) (MUS MUSCULUS VH (IGHV8-8*01 (77%) (IGHD)-IGHJ4*01 (93%))
Systematic Name English
ZMAPP COMPONENT C13C6FR1
Common Name English
13C6
Code English
cosfroviximab [INN]
Common Name English
C13C6FR1
Code English
COSFROVIXIMAB [USAN]
Common Name English
Cosfroviximab [WHO-DD]
Common Name English
ZMAPP COMPONENT C13C6
Brand Name English
ZMAPP COMPONENT C13C6-FR1
Common Name English
C13C6-FR1
Code English
MB-003 COMPONENT C13C6-FR1
Common Name English
IMMUNOGLOBULIN G1, ANTI-(EBOLAVIRUS/RESTON EBOLAVIRUS/SUDAN EBOLAVIRUS/TAI FOREST EBOLAVIRUS GLYCOPROTEIN) (HUMAN-MUS MUSCULUS MONOCLONAL C13C6-FR1 HEAVY CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL C13C6-FR1 .KAPPA.-CHAIN, DIMER
Common Name English
Classification Tree Code System Code
FDA ORPHAN DRUG 440914
Created by admin on Sat Dec 16 11:24:20 GMT 2023 , Edited by admin on Sat Dec 16 11:24:20 GMT 2023
Code System Code Type Description
FDA UNII
820CI2BHRP
Created by admin on Sat Dec 16 11:24:20 GMT 2023 , Edited by admin on Sat Dec 16 11:24:20 GMT 2023
PRIMARY
CAS
1792982-57-0
Created by admin on Sat Dec 16 11:24:20 GMT 2023 , Edited by admin on Sat Dec 16 11:24:20 GMT 2023
PRIMARY
NCI_THESAURUS
C171831
Created by admin on Sat Dec 16 11:24:20 GMT 2023 , Edited by admin on Sat Dec 16 11:24:20 GMT 2023
PRIMARY
USAN
DE-19
Created by admin on Sat Dec 16 11:24:20 GMT 2023 , Edited by admin on Sat Dec 16 11:24:20 GMT 2023
PRIMARY
INN
10535
Created by admin on Sat Dec 16 11:24:20 GMT 2023 , Edited by admin on Sat Dec 16 11:24:20 GMT 2023
PRIMARY
From To
1_22 1_97
1_149 1_205
1_225 3_213
1_231 2_231
1_234 2_234
1_266 1_326
1_372 1_430
2_22 2_97
2_149 2_205
2_225 4_213
2_266 2_326
2_372 2_430
3_23 3_88
3_133 3_193
4_23 4_88
4_133 4_193
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_302
N 2_302
Related Record Type Details
TARGET->LIGAND
TARGET ORGANISM->INHIBITOR
Does not inhibit virus directly in-vitro. May rely on complement for in-vivo activity.
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL