TILIQUINOL

Details

Stereochemistry	ACHIRAL
Molecular Formula	C10H9NO
Molecular Weight	159.1846
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC1=CC=C(O)C2=C1C=CC=N2

InChI

InChIKey=RPVGLMKJGQMQSN-UHFFFAOYSA-N

InChI=1S/C10H9NO/c1-7-4-5-9(12)10-8(7)3-2-6-11-10/h2-6,12H,1H3

HIDE SMILES / InChI

Molecular Formula	C10H9NO
Molecular Weight	159.1846
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: http://sante-medecine.journaldesfemmes.com/faq/31020-intetrix-indications-posologie-et-effets-secondaires | https://www.ncbi.nlm.nih.gov/pubmed/26088504

Tiliquinol in combination with tilbroquinol and tiliquinol lauryl sulfate are the active components of Intetrix, a medicine prescribed to adults who suffer from amoebiasis. Amoebiasis refers to an infection caused by the parasite Entamoeba histolytica. Intetrix is marketed as a capsule and is administered orally.

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Amoebiasis 11 Sources: http://sante-medecine.journaldesfemmes.com/faq/31020-intetrix-indications-posologie-et-effets-secondaires	Curative		Phase I 428	INTETRIX Approved Use Unknown

Sourcing

Vendor/Aggregator	ID	URL
1PlusChem LLC	1P00DJHU	https://www.1pchem.com/search?query=1P00DJHU
A2B Chem	AG30994	http://a2bchem.com/prod/AG30994
AA Blocks	AA00DIYE	http://aablocks.com/goods/Goods/detail?id=AA00DIYE
AK Scientific	8090AB	https://aksci.com/item_detail.php?cat=8090AB
Achemo Scientific Limited	AC-44691	http://www.achemo.com/search/?Keyword=AC-44691
Alfa Chemistry	ACM5541673	http://www.alfa-chemistry.com/search.aspx?q=ACM5541673
Alinda	ALBB-027828	http://alinda.ru/finechem_en_.html?i=ALBB-027828
Ambeed	A260708	http://www.ambeed.com/search/Search.html?keyword=A260708
AstaTech	AB1120	http://astatechinc.com/CPSResult.php?CRNO=AB1120
Chem Scene	CS-W019183	http://www.chemscene.com/goproductList/searchProductList?productObj=CS-W019183
ChemBridge	5511450	http://www.hit2lead.com/screening-compounds/5511450
ChemDiv	BB58-1201	http://chemistryondemand.com:8080/eShop/search_results.jsp?idnumber=BB58-1201
Combi-Blocks	ST-5140	http://www.combi-blocks.com/cgi-bin/find.cgi?ST-5140
Debye Scientific	DB-016624	https://www.debyesci.com/index.php?id=product&ext[cno]=DB-016624
Enamine	BBV-38270228	http://www.enaminestore.com/catalog/BBV-38270228
Fluorochem	235465	http://www.fluorochem.co.uk/Products/Product?code=235465
Hairui	HR154933	http://www.hairuichem.com/en/product/search.do?q=HR154933
KeyOrganics	DS-18629	http://www.keyorganicsinc.com/bionet/catalogsearch/result?q=DS-18629
Lab Network	LN00005026	https://labnetwork.com/frontend-app/p/#!/moleculedetails/LN00005026
Lab Seeker	SC-98354	http://www.labseeker.com/search.php?keywords=SC-98354&category=0
LabSeeker	SC-98354	http://www.labseeker.com/search.php?keywords=SC-98354&category=0
Matrix Scientific	119811	http://www.matrixscientific.com/119811.html
MolPort	MolPort-003-181-740	https://www.molport.com/shop/molecule-link/MolPort-003-181-740
SynQuest	4H01-1-AE	http://www.synquestlabs.com/search-result.html?q=4H01-1-AE
Synthonix	M69187	https://synthonix.com/catalogsearch/result/?q=M69187
TimTec	ST50976389	http://www.echemstore.com/catalogsearch/result/?q=ST50976389
Toronto Research Chemicals	M329348	https://www.trc-canada.com/product-detail/?CatNum=M329348
Wonderchem	WD06C8T	http://www.wonder-chem.com/search.html?text=WD06C8T
WuXi AppTec	WX649085	https://www.labnetwork.com/frontend-app/p/#!/supplier/wuxi/product/WX649085
eMolecules	107056494	https://orderbb.emolecules.com/search/#?query=107056494
eMolecules	7450853	https://orderbb.emolecules.com/search/#?query=7450853
eNovation Chemicals	D766015	https://www.enovationchem.com/Products.asp?SEARCHTEXT=D766015&searchbtn.x=0&searchbtn.y=0
mcule	MCULE-1998544820	https://mcule.com/MCULE-1998544820/

PubMed

Title	Date	PubMed
[Neuropathy and ocular involvement following prolonged use of tilbroquinol and tiliquinol].	1985 Jan	3923584
[Resistance of Vibrio cholerae 0:1 to the 0/129 compound and multiresistance to antibiotics].	1992	1327350
[In vitro sensitivity of Vibrio cholerae serotype 0:139 to an intestinal antiseptic tiliquinol-tilbroquinol combination].	1994	8003903

Patents

Sample Use Guides

In Vivo Use Guide

The recommended daily dose is 4 capsules of Intetrix (2 in the morning and 2 in the evening) for 10 days. It is best to take the capsules before meals.

Route of Administration: Oral

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:46:39 GMT 2023` Edited by `admin` on `Fri Dec 15 15:46:39 GMT 2023`
Record UNII	813OG1OGVG
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

TILIQUINOL

Official Name

English

Tiliquinol [WHO-DD]

Common Name

English

TILIQUINOL [MART.]

Common Name

English

5-METHYL-8-QUINOLINOL

Systematic Name

English

NSC-130828

Code

English

5-METHYLQUINOLIN-8-OL

Systematic Name

English

5-METHYL-8-HYDROXYQUINOLINE

Systematic Name

English

tiliquinol [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C254