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Details

Stereochemistry ACHIRAL
Molecular Formula 3C2H3O2.Al
Molecular Weight 204.1136
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of Aluminum acetate

SMILES

[Al+3].CC([O-])=O.CC([O-])=O.CC([O-])=O

InChI

InChIKey=WCOATMADISNSBV-UHFFFAOYSA-K
InChI=1S/3C2H4O2.Al/c3*1-2(3)4;/h3*1H3,(H,3,4);/q;;;+3/p-3

HIDE SMILES / InChI

Molecular Formula C2H3O2
Molecular Weight 59.044
Charge -1
Count
MOL RATIO 3 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula Al
Molecular Weight 26.9815
Charge 3
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Burow invented an astringent antiseptic solution of aluminium acetate in water to relieve the itching and inflammation of minor skin irritations. At present the oflicial U. S. P. procedure to made Burow's solution involves the reaction of aluminum sulfate, calcium carbonate and acetic acid to form aluminum sub-acetate, also termed basic aluminum acetate. The solution is available as an over-the-counter drug for topical administration, with brand names including Domeboro. Burow's solution has been shown to be effective against chronic suppurative otitis media and otitis externa. It is active against bacteria resulting in damage to the cell wall.

Originator

Approval Year

Targets

Primary TargetPharmacologyConditionPotency

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
DOMEBORO
Curative
DOMEBORO

PubMed

Sample Use Guides

In Vivo Use Guide
DOMEBORO® SOOTHING SOAK – dissolve 1 to 3 packets in a pint (16 oz) of cool or warm water – stir until fully dissolved; do not strain or filter. The resulting mixture contains 0.16% (1 packet), 0.32% (2 packets), or 0.48% (3 packets) aluminum acetate and is ready for use For use as a soak: – soak affected area for 15 to 30 minutes as needed, or as directed by a doctor – repeat 3 times a day or as directed by a doctor – discard solution after each use. For use as a compress or wet dressing: – soak a clean, soft cloth in the solution. – apply cloth loosely to affected area for 15 to 30 minutes – repeat as needed or as directed by a doctor – discard solution after each use
Route of Administration: Topical
In Vitro Use Guide
Burow's solution (13% aluminum subacetate) is active against S. aureus and P. aeruginosa, resulting in damage to the cell wall.
Substance Class Chemical
Record UNII
80EHD8I43D
Record Status Validated (UNII)
Record Version