TIAPIRINOL

Details

Stereochemistry	MIXED
Molecular Formula	C12H16N2O4S
Molecular Weight	284.331
Optical Activity	UNSPECIFIED
Defined Stereocenters	0 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC1=NC=C(CO)C(C2NC(CCS2)C(O)=O)=C1O

InChI

InChIKey=ZLIAWSCQKUNLSI-UHFFFAOYSA-N

InChI=1S/C12H16N2O4S/c1-6-10(16)9(7(5-15)4-13-6)11-14-8(12(17)18)2-3-19-11/h4,8,11,14-16H,2-3,5H2,1H3,(H,17,18)

HIDE SMILES / InChI

Molecular Formula	C12H16N2O4S
Molecular Weight	284.331
Charge	0
Count

Stereochemistry	MIXED
Additional Stereochemistry	No
Defined Stereocenters	0 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: Bitamin (1967), 35, (4), 322-33. | https://worldwide.espacenet.com/publicationDetails/biblio?DB=EPODOC&II=0&ND=3&adjacent=true&locale=en_EP&FT=D&date=19670222&CC=GB&NR=1059896A&KC=A

Tiapirinol is a thiazine derivative patented by Tanabe Seiyaku Co., Ltd. as a low toxic compound useful to prevent hypohepatia. In acute toxicity tests on mice, the toxicity of Tiapirinol is lower than that of pyridoxal phosphate and other vitamin B6 derivative. Tiapirinol showed vitamin B6 activity approximately equivalent to that of pyridoxal phosphate or pyridoxine for the growth of vitamin B6 deficient rats and also for the convulsions caused by antivitamin B6 agents.

Originator

Approval Year

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:08:09 GMT 2025` Edited by `admin` on `Mon Mar 31 18:08:09 GMT 2025`
Record UNII	7ZRJ2BMC6X
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

TIAPIRINOL

Official Name

English

tiapirinol [INN]

Preferred Name

English

TETRAHYDRO-2-(3-HYDROXY-5-(HYDROXYMETHYL)-2-METHYL-4-PYRIDYL)-2H-1,3-THIAZINE-4-CARBOXYLIC ACID

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C26017