Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C8H15NO |
| Molecular Weight | 141.2108 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 3 / 3 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CN1[C@H]2CC[C@@H]1C[C@H](O)C2
InChI
InChIKey=CYHOMWAPJJPNMW-JIGDXULJSA-N
InChI=1S/C8H15NO/c1-9-6-2-3-7(9)5-8(10)4-6/h6-8,10H,2-5H2,1H3/t6-,7+,8+
| Molecular Formula | C8H15NO |
| Molecular Weight | 141.2108 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 3 / 3 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Tropine is a naturally-occurring tropane alkaloid, which can be obtained from tropinone under the action of Tropinone reductases I. Tropine serves as an intermediate in the synthesis of different bioactive alkaloids, including atropine. In 1950th was published an article, where was described the use tropine in the treatment of angina pectoris. But in further articles were mentioned the derivative of tropine, atropine for the treatment of this disease.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Structure-activity relationships among derivatives of dicarboxylic acid esters of tropine. | 2002 Oct |
|
| Calystegines in wild and cultivated Erythroxylum species. | 2005 Jun |
|
| Quaternary derivatives of granatanol diesters: potent, ultrashort acting non-depolarizing neuromuscular relaxants. | 2006 Jul 4 |
|
| The functional divergence of short-chain dehydrogenases involved in tropinone reduction. | 2008 May |
|
| Treatment of Cushing disease: overview and recent findings. | 2010 Oct 21 |
Patents
| Substance Class |
Chemical
Created
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admin
on
Edited
Sat Dec 16 05:14:33 GMT 2023
by
admin
on
Sat Dec 16 05:14:33 GMT 2023
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| Record UNII |
7YXR19M72Y
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| Record Status |
Validated (UNII)
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NCI_THESAURUS |
C29704
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| Code System | Code | Type | Description | ||
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57554
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DTXSID2049399
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TROPINE
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7YXR19M72Y
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C005864
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15884
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C61994
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204-384-2
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120-29-6
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43870
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m11230
Created by
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PRIMARY | Merck Index |
| Related Record | Type | Details | ||
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PARENT -> IMPURITY |
CHROMATOGRAPHIC PURITY (TLC)
EP
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ACTIVE MOIETY |
