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Details

Stereochemistry ABSOLUTE
Molecular Formula 2C5H6NO3.Ca
Molecular Weight 296.29
Optical Activity UNSPECIFIED
Defined Stereocenters 2 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CALCIUM PIDOLATE

SMILES

[Ca++].[O-]C(=O)[C@@H]1CCC(=O)N1.[O-]C(=O)[C@@H]2CCC(=O)N2

InChI

InChIKey=YQFZERWESBDNRJ-QHTZZOMLSA-L
InChI=1S/2C5H7NO3.Ca/c2*7-4-2-1-3(6-4)5(8)9;/h2*3H,1-2H2,(H,6,7)(H,8,9);/q;;+2/p-2/t2*3-;/m00./s1

HIDE SMILES / InChI

Molecular Formula C5H6NO3
Molecular Weight 128.106
Charge -1
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 1 / 1
E/Z Centers 0
Optical Activity UNSPECIFIED

Molecular Formula Ca
Molecular Weight 40.078
Charge 2
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

In calcium pidolate, the calcium ion is bound to two molecules of pyrrolidone carboxylic acid that act as protein supports. None of the calcium salts currently employed therapeutically (chloride, carbonate, lactate, gluconate, glucoheptonate, gluconolactate, gluconogalactogluconate, lactobionate, etc.) contain a protein support. Calcium pidolate is the only drug in which the calcium is transported by a protein substrate that is directly assimilable and specific to the body's bony matrix. Calcium pidolate can help the body's own calcium in performing its two primary roles: in any adverse changes in bony tissue during its growth, during bone ageing or traumatic bone lesions, Calcium pidolate can provide both a protein framework and a mineral source, as regards various metabolic functions of calcium, calcium pidolate have demonstrated that the substance is perfectly absorbed and distributed throughout various tissues and that it stimulates numerous hormonal and metabolic activities. In the treatment of various forms of osteoporosis with calcium pidolate, it is used curatively.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Unknown

Approved Use

Unknown

Sample Use Guides

Calcium Pidolate, orally, at an equimolar dose of 135 mg/kg Ca2+ per day
Route of Administration: Oral
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:38:49 GMT 2023
Edited
by admin
on Fri Dec 15 15:38:49 GMT 2023
Record UNII
7Y2LVU5EKK
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
CALCIUM PIDOLATE
MART.   WHO-DD  
Common Name English
CALCIUM PIDOLATE [MART.]
Common Name English
CALCIUM L-PYROGLUTAMATE
Common Name English
L-PYRROLIDONE CARBOXYLIC ACID, CALCIUM SALT
Common Name English
L-CALCIUM PIDOLATE
Common Name English
CALCIDONE
Brand Name English
PIDOLIC ACID CALCIUM SALT (2:1)
Common Name English
CALCIUM PCA [INCI]
Common Name English
L-PROLINE, 5-OXO-, CALCIUM SALT (2:1)
Common Name English
PROLINE, 5-OXO-, CALCIUM SALT (2:1), L-
Common Name English
5-OXO-L-PROLINE CALCIUM SALT
Common Name English
Calcium pidolate [WHO-DD]
Common Name English
EFICAL
Brand Name English
CALCIUM OXOPROLINE
Systematic Name English
CALCIUM PCA
INCI  
INCI  
Official Name English
Code System Code Type Description
RXCUI
87393
Created by admin on Fri Dec 15 15:38:49 GMT 2023 , Edited by admin on Fri Dec 15 15:38:49 GMT 2023
PRIMARY RxNorm
FDA UNII
7Y2LVU5EKK
Created by admin on Fri Dec 15 15:38:49 GMT 2023 , Edited by admin on Fri Dec 15 15:38:49 GMT 2023
PRIMARY
DAILYMED
7Y2LVU5EKK
Created by admin on Fri Dec 15 15:38:49 GMT 2023 , Edited by admin on Fri Dec 15 15:38:49 GMT 2023
PRIMARY
EPA CompTox
DTXSID501019893
Created by admin on Fri Dec 15 15:38:49 GMT 2023 , Edited by admin on Fri Dec 15 15:38:49 GMT 2023
PRIMARY
SMS_ID
100000090379
Created by admin on Fri Dec 15 15:38:49 GMT 2023 , Edited by admin on Fri Dec 15 15:38:49 GMT 2023
PRIMARY
MESH
C092985
Created by admin on Fri Dec 15 15:38:49 GMT 2023 , Edited by admin on Fri Dec 15 15:38:49 GMT 2023
PRIMARY
ECHA (EC/EINECS)
250-602-4
Created by admin on Fri Dec 15 15:38:49 GMT 2023 , Edited by admin on Fri Dec 15 15:38:49 GMT 2023
PRIMARY
CAS
31377-05-6
Created by admin on Fri Dec 15 15:38:49 GMT 2023 , Edited by admin on Fri Dec 15 15:38:49 GMT 2023
PRIMARY
PUBCHEM
14559044
Created by admin on Fri Dec 15 15:38:49 GMT 2023 , Edited by admin on Fri Dec 15 15:38:49 GMT 2023
PRIMARY
EVMPD
SUB13194MIG
Created by admin on Fri Dec 15 15:38:49 GMT 2023 , Edited by admin on Fri Dec 15 15:38:49 GMT 2023
PRIMARY
Related Record Type Details
PARENT -> SALT/SOLVATE