U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS
Angiotensinamide is octapeptide amide of bovine angiotensin II used to increase blood pressure by vasoconstriction. Angiotensinamide is indicated for the treatment of severe hypotension unresponsive to traditional pressor agents. Angiotensinamide has a strong pressure effect, due to the increased peripheral resistance of blood vessels, especially small caliber arterioles. Under the influence of angiotensinamide, the vessels of the internal organs, skin, kidneys are particularly narrowed. Blood circulation in skeletal muscles and coronary vessels does not change significantly. The drug has no direct effect on the heart and does not cause arrhythmias in therapeutic doses. Angiotensinamide is rapidly inactivated by enzymes contained in the blood, and therefore, when administered once, it has a short-term (2–3 min) pressure effect. However, the duration of the effect can be relatively easily controlled by selecting the appropriate rate of administration of the drug solution.

Approval Year

PubMed

PubMed

TitleDatePubMed
[Induction of "epinephrine myocarditis" by hypertensin. Light- and electron-microscopic studies (author's transl)].
1974
Cerebrovascular permeability to horseradish peroxidase in hypertensive rats: effects of unilateral locus ceruleus lesion.
1987
Substance Class Protein
Created
by admin
on Sat Dec 16 01:00:10 GMT 2023
Edited
by admin
on Sat Dec 16 01:00:10 GMT 2023
Protein Sub Type
Sequence Type COMPLETE
Record UNII
7WAL1X78KV
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ANGIOTENSIN AMIDE
MI   USAN  
USAN  
Official Name English
Angiotensinamide [WHO-DD]
Common Name English
ASN-ARG-VAL-TYR-VAL-HIS-PRO-PHE
Common Name English
N-(1-(N-(N-(N-(N-(N2-L-ASPARAGINYL-L-ARGINYL)-L-VALYL)-L-TYROSYL)-L-VALYL)-L-HISTIDYL)-L-PROLYL)-3-PHENYL-L-ALANINE
Systematic Name English
ANGIOTENSIN AMIDE [MI]
Common Name English
ANGIOTENSIN AMIDE [USAN]
Common Name English
ANGIOTENSINAMIDE
INN   MART.   WHO-DD  
INN  
Official Name English
angiotensinamide [INN]
Common Name English
ANGIOTENSINAMIDE [MART.]
Common Name English
NSC-107678
Code English
ANGIOTENSIN II, 1-L-ASPARAGINE-5-L-VALINE-
Common Name English
1-L-ASPARAGINE-5-L-VALINEANGIOTENSIN II
Common Name English
Classification Tree Code System Code
WHO-ATC C01CX06
Created by admin on Sat Dec 16 01:00:10 GMT 2023 , Edited by admin on Sat Dec 16 01:00:10 GMT 2023
NCI_THESAURUS C548
Created by admin on Sat Dec 16 01:00:10 GMT 2023 , Edited by admin on Sat Dec 16 01:00:10 GMT 2023
WHO-VATC QC01CX06
Created by admin on Sat Dec 16 01:00:10 GMT 2023 , Edited by admin on Sat Dec 16 01:00:10 GMT 2023
Code System Code Type Description
NSC
107678
Created by admin on Sat Dec 16 01:00:10 GMT 2023 , Edited by admin on Sat Dec 16 01:00:10 GMT 2023
PRIMARY
DRUG BANK
DB13517
Created by admin on Sat Dec 16 01:00:10 GMT 2023 , Edited by admin on Sat Dec 16 01:00:10 GMT 2023
PRIMARY
MERCK INDEX
m1914
Created by admin on Sat Dec 16 01:00:10 GMT 2023 , Edited by admin on Sat Dec 16 01:00:10 GMT 2023
PRIMARY Merck Index
EPA CompTox
DTXSID401018923
Created by admin on Sat Dec 16 01:00:10 GMT 2023 , Edited by admin on Sat Dec 16 01:00:10 GMT 2023
PRIMARY
FDA UNII
7WAL1X78KV
Created by admin on Sat Dec 16 01:00:10 GMT 2023 , Edited by admin on Sat Dec 16 01:00:10 GMT 2023
PRIMARY
EVMPD
SUB05511MIG
Created by admin on Sat Dec 16 01:00:10 GMT 2023 , Edited by admin on Sat Dec 16 01:00:10 GMT 2023
PRIMARY
CAS
53-73-6
Created by admin on Sat Dec 16 01:00:10 GMT 2023 , Edited by admin on Sat Dec 16 01:00:10 GMT 2023
PRIMARY
CHEBI
2719
Created by admin on Sat Dec 16 01:00:10 GMT 2023 , Edited by admin on Sat Dec 16 01:00:10 GMT 2023
PRIMARY
DRUG CENTRAL
4338
Created by admin on Sat Dec 16 01:00:10 GMT 2023 , Edited by admin on Sat Dec 16 01:00:10 GMT 2023
PRIMARY
PUBCHEM
10351092
Created by admin on Sat Dec 16 01:00:10 GMT 2023 , Edited by admin on Sat Dec 16 01:00:10 GMT 2023
PRIMARY
ChEMBL
CHEMBL409803
Created by admin on Sat Dec 16 01:00:10 GMT 2023 , Edited by admin on Sat Dec 16 01:00:10 GMT 2023
PRIMARY
ECHA (EC/EINECS)
200-182-3
Created by admin on Sat Dec 16 01:00:10 GMT 2023 , Edited by admin on Sat Dec 16 01:00:10 GMT 2023
PRIMARY
INN
1057
Created by admin on Sat Dec 16 01:00:10 GMT 2023 , Edited by admin on Sat Dec 16 01:00:10 GMT 2023
PRIMARY
WIKIPEDIA
ANGIOTENSINAMIDE
Created by admin on Sat Dec 16 01:00:10 GMT 2023 , Edited by admin on Sat Dec 16 01:00:10 GMT 2023
PRIMARY
NCI_THESAURUS
C77008
Created by admin on Sat Dec 16 01:00:10 GMT 2023 , Edited by admin on Sat Dec 16 01:00:10 GMT 2023
PRIMARY
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL