MAGNESIUM ADIPATE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C6H8O4.Mg
Molecular Weight	168.4303
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[Mg++].[O-]C(=O)CCCCC([O-])=O

InChI

InChIKey=QXNFATVALXHNRJ-UHFFFAOYSA-L

InChI=1S/C6H10O4.Mg/c7-5(8)3-1-2-4-6(9)10;/h1-4H2,(H,7,8)(H,9,10);/q;+2/p-2

HIDE SMILES / InChI

Molecular Formula	Mg
Molecular Weight	24.305
Charge	2
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C6H8O4
Molecular Weight	144.1253
Charge	-2
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/10907229
Curator's Comment: description was created based on several sources, including: http://drug-info.in/magnesium-magnesium-adipate-apogepha-arzneimittel/ | Seelig, M.S. (2012) "Magnesium Deficiency in the Pathogenesis of Disease", p.146 Retrieved from https://books.google.ru/books?id=dP_pBwAAQBAJ | https://www.ncbi.nlm.nih.gov/pubmed/7224794

Magnesium adipate is a magnesium salt. It was reported that treatment with a preparation containing magnesium adipate and magnesium nicotinate (in tablet or ampule form for i.v. or i.m. administration) has been useful in the treatment of patients with coronary, cerebral and peripheral atherosclerosis.

Approval Year

Conditions

Condition	Modality	Highest Phase	Product
Hypomagnesemia 3 Sources: https://www.ncbi.nlm.nih.gov/pubmed/7224794 https://www.ncbi.nlm.nih.gov/pubmed/1190966	Curative	Not Provided 504	Magnesium Approved Use Unknown
Thromboembolism 8 Sources: https://www.ncbi.nlm.nih.gov/pubmed/13846794	Preventing	Not Provided 504	Magnesium Approved Use Unknown
Atherosclerosis 74 Sources: Seelig, M.S. (2012) 'Magnesium Deficiency in the Pathogenesis of Disease', p.146 Retrieved from https://books.google.ru/books?id=dP_pBwAAQBAJ	Primary	Not Provided 504	Magnesium Approved Use Unknown

PubMed

Title	Date	PubMed
[Research on changes in the serum magnesium level during thromboembolism prevention with magnesium adipate].	1960 Apr 28	13846794
[Calcium, magnesium, phosphorus, chloride and glucose in the blood of cattle following intravenous infusion of solutions with various calcium and magnesium concentration aimed at improving the treatment of hypomagnesemia].	1975 Jun	1190966
[Blood mineral (Ca, Mg, Na K, Pa) levels and aspartate aminotransferase, leucine aminopeptidase, creatine phosphokinase and alkaline phosphatase activity and blood glucose levels in cattle with hypomagnesemia prior to and following infusion of a 500 ml solution containing 60 g of Mg adipate and 60 g of Ca gluconate].	1981	7224794
[Modification of blood serum mineral levels and aspartate aminotransferase, leucine aminopeptidase and alkaline phosphatase activity and plasma in glucose levels in healthy cattle by Ca-Mg-containing solutions].	1981	7224793
Effect of intravenous magnesium on ventricular tachyarrhythmias associated with acute myocardial infarction.	2000 Jun	10907229
Influence of selected auxiliary substances on some physicochemical properties of solid dispersions containing magnesium salts.	2004 Mar-Apr	15493290

Patents

Sample Use Guides

In Vivo Use Guide

3 x 2 coated tablets (= 300 mg Mg/24 h or 12.34 mmol Mg/24 h, respectively).

Route of Administration: Oral

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Sat Dec 16 06:18:13 GMT 2023` Edited by `admin` on `Sat Dec 16 06:18:13 GMT 2023`
Record UNII	7SU414350A
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

MAGNESIUM ADIPATE

Systematic Name

English

NSC-85380

Code

English

ADIPIC ACID, MAGNESIUM SALT

Common Name

English

HEXANEDIOIC ACID, MAGNESIUM SALT (1:1)

Common Name

English

Magnesium adipate [WHO-DD]

Common Name

English

ADIPIC ACID, MAGNESIUM SALT (1:1)

Common Name

English

Code System Code Type Description

CAS

7486-39-7