25D-NBOME

COC1=CC=CC=C1CNCCC2=CC(OC)=C(C)C=C2OC

InChIKey=UTVHBNXCFSATDB-UHFFFAOYSA-N

InChI=1S/C19H25NO3/c1-14-11-19(23-4)15(12-18(14)22-3)9-10-20-13-16-7-5-6-8-17(16)21-2/h5-8,11-12,20H,9-10,13H2,1-4H3

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Targets

Primary Target	Pharmacology	Condition	Potency
Serotonin 2c (5-HT2c) receptor 131 Target ID: CHEMBL225 Sources: https://www.ncbi.nlm.nih.gov/pubmed/30261175	Agonist 2752		1.37 nM [EC50]
Serotonin 2a (5-HT2a) receptor 237 Target ID: CHEMBL224 Sources: https://www.ncbi.nlm.nih.gov/pubmed/30261175	Agonist 2752		1.53 nM [EC50]

PubMed

Title	Date	PubMed
Neurochemical pharmacology of psychoactive substituted N-benzylphenethylamines: High potency agonists at 5-HT2A receptors.	2018-12	30261175
In vitro phase I metabolism of three phenethylamines 25D-NBOMe, 25E-NBOMe and 25N-NBOMe using microsomal and microbial models.	2018-10	29971945
Analysis of 25I-NBOMe, 25B-NBOMe, 25C-NBOMe and Other Dimethoxyphenyl-N-[(2-Methoxyphenyl) Methyl]Ethanamine Derivatives on Blotter Paper.	2015-10	26378135

Substance Class	Chemical Created by `admin` on `Mon Mar 31 23:21:17 GMT 2025` Edited by `admin` on `Mon Mar 31 23:21:17 GMT 2025`
Record UNII	7RET11HE13
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

25D-NBOME

Common Name

English

2C-D-NBOME

Preferred Name

English

CIMBI-138

Common Name

English

BENZENEETHANAMINE, 2,5-DIMETHOXY-N-((2-METHOXYPHENYL)METHYL)-4-METHYL-

Systematic Name

English

2,5-DIMETHOXY-N-((2-METHOXYPHENYL)METHYL)-4-METHYLBENZENEETHANAMINE

Systematic Name

English

2-(2,5-DIMETHOXY-4-METHYLPHENYL)-N-(2-METHOXYBENZYL)ETHANAMINE

Systematic Name

English

Classification Tree Code System Code

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