Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C38H70N2O13 |
| Molecular Weight | 762.968 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 18 / 18 |
| E/Z Centers | 1 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]3O[C@H](C)C[C@@H]([C@H]3O)N(C)C)[C@](C)(O)C[C@@H](C)\C(=N/OC)[C@H](C)[C@@H](O)[C@]1(C)O
InChI
InChIKey=HPZGUSZNXKOMCQ-SQYJNGITSA-N
InChI=1S/C38H70N2O13/c1-15-26-38(10,46)31(42)21(4)28(39-48-14)19(2)17-36(8,45)33(53-35-29(41)25(40(11)12)16-20(3)49-35)22(5)30(23(6)34(44)51-26)52-27-18-37(9,47-13)32(43)24(7)50-27/h19-27,29-33,35,41-43,45-46H,15-18H2,1-14H3/b39-28+/t19-,20-,21+,22+,23-,24+,25+,26-,27+,29-,30+,31-,32+,33-,35+,36-,37-,38-/m1/s1
| Molecular Formula | C38H70N2O13 |
| Molecular Weight | 762.968 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 18 / 18 |
| E/Z Centers | 1 |
| Optical Activity | UNSPECIFIED |
Lexithromycin is an early semi-synthetic erythromycin, prepared by reaction of the 9-keto moiety to methyl oxime. Lexithromycin has improved absorption in vivo over erythromycin due to increased hydrophopicity and pH stability. Like all erythromycins, lexithromycin shows broad spectrum antibacterial activity and acts by binding to the 30S and 50S ribosomal sub-units, blocking protein synthesis. Formulations containing lexithromycin were tested in clinical trials as treatment for HIV but were discontinued.
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 21:26:28 GMT 2025
by
admin
on
Mon Mar 31 21:26:28 GMT 2025
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| Record UNII |
7QKO29734U
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| Record Status |
Validated (UNII)
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| Record Version |
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Official Name | English | ||
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Preferred Name | English | ||
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Common Name | English | ||
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| Classification Tree | Code System | Code | ||
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NCI_THESAURUS |
C261
Created by
admin on Mon Mar 31 21:26:28 GMT 2025 , Edited by admin on Mon Mar 31 21:26:28 GMT 2025
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| Code System | Code | Type | Description | ||
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6532846
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118244-59-0
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53066-26-5
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7QKO29734U
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6785
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C87760
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CHEMBL2106397
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100000082287
Created by
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PRIMARY | |||
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SUB08499MIG
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admin on Mon Mar 31 21:26:28 GMT 2025 , Edited by admin on Mon Mar 31 21:26:28 GMT 2025
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CC-11
Created by
admin on Mon Mar 31 21:26:28 GMT 2025 , Edited by admin on Mon Mar 31 21:26:28 GMT 2025
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PRIMARY |
| Related Record | Type | Details | ||
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ACTIVE MOIETY |
