Approval Year
| Substance Class |
Protein
Created
by
admin
on
Edited
Tue Apr 01 18:13:21 GMT 2025
by
admin
on
Tue Apr 01 18:13:21 GMT 2025
|
| Protein Type | RECEPTOR |
| Protein Sub Type | |
| Sequence Origin | HUMAN |
| Sequence Type | COMPLETE |
| Record UNII |
7Q6KJ2Q69D
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Preferred Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
Q03431
Created by
admin on Tue Apr 01 18:13:21 GMT 2025 , Edited by admin on Tue Apr 01 18:13:21 GMT 2025
|
PRIMARY | |||
|
7Q6KJ2Q69D
Created by
admin on Tue Apr 01 18:13:21 GMT 2025 , Edited by admin on Tue Apr 01 18:13:21 GMT 2025
|
PRIMARY |
| From | To |
|---|---|
| 1_22 | 1_91 |
| 1_82 | 1_122 |
| 1_105 | 1_144 |
| Glycosylation Type | HUMAN |
| Glycosylation Link Type | Site |
|---|---|
| N | 1_125 |
| N | 1_135 |
| N | 1_140 |
| N | 1_150 |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
|
AGONIST -> TARGET |
This results in activation of the cAMP signaling pathway in target cells. In rats and monkeys, abaloparatide had an anabolic effect on bone, demonstrated by increases in BMD and bone mineral content (BMC) that correlated with increases in bone strength at vertebral and/or nonvertebral sites.
ACTIVATOR
EC50
|
||
|
AGONIST -> TARGET | |||
|
AGONIST -> TARGET |
|
||
|
|
AGONIST -> TARGET |
|
Structural Modifications
| Modification Type | Location Site | Location Type | Residue Modified | Extent | Fragment Name | Fragment Approval |
|---|---|---|---|---|---|---|
| AMINO_ACID_SUBSTITUTION | [1_525] | SITE_SPECIFIC | T | THREONINE PHOSPHATE | 3L4WX7B1EI |
| Name | Property Type | Amount | Referenced Substance | Defining | Parameters | References |
|---|---|---|---|---|---|---|
| MOL_WEIGHT | CHEMICAL |
|
||||
| Molecular Formula | CHEMICAL |
|