Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C17H19FN4O5S |
| Molecular Weight | 410.42 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CN1C(=O)C(O)=C(N=C1N2CCCCS2(=O)=O)C(=O)NCC3=CC=C(F)C=C3
InChI
InChIKey=VNIWZCGZPBJWBI-UHFFFAOYSA-N
InChI=1S/C17H19FN4O5S/c1-21-16(25)14(23)13(15(24)19-10-11-4-6-12(18)7-5-11)20-17(21)22-8-2-3-9-28(22,26)27/h4-7,23H,2-3,8-10H2,1H3,(H,19,24)
| Molecular Formula | C17H19FN4O5S |
| Molecular Weight | 410.42 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
DescriptionCurator's Comment: Description was created based on several sources, including
http://www.selleckchem.com/products/BMS-707035.html
Curator's Comment: Description was created based on several sources, including
http://www.selleckchem.com/products/BMS-707035.html
BMS-707035 is a potent, specific, and reversible HIV-I integrase (IN) inhibitor that blocks HIV IN strand transfer activity. Bristol-Myers Squibb was developing BMS-707035 for the treatment of HIV infections, however development was discontinued.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| 3-Hydroxy-6,7-dihydropyrimido[2,1-c][1,4]oxazin-4(9H)-ones as new HIV-1 integrase inhibitors WO2011046873 A1. | 2011-11 |
|
| Anti-infectives: clinical progress of HIV-1 integrase inhibitors. | 2008-06 |
|
| Changes to the HIV long terminal repeat and to HIV integrase differentially impact HIV integrase assembly, activity, and the binding of strand transfer inhibitors. | 2007-10-26 |
|
| HIV-1 integrase inhibitors: an emerging clinical reality. | 2007 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 23:41:24 GMT 2025
by
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on
Mon Mar 31 23:41:24 GMT 2025
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| Record UNII |
7PR4P7YOKT
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| Record Status |
Validated (UNII)
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| Record Version |
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