Rilimogene Glafolivec

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Structurally Diverse Created by `admin` on `Sat Dec 16 19:46:00 GMT 2023` Edited by `admin` on `Sat Dec 16 19:46:00 GMT 2023`
Source Materials Class	ORGANISM
Source Materials Type	RECOMBINANT VIRUS
Source Materials State	LIVE NON-REPLICATING GENETICALLY MODIFIED
Organism Family	Poxviridae
Organism Genus	Avipoxvirus
Organism Species	fowlpox virus
Infraspecific Type	RECOMBINANT VECTOR
Infraspecific Name	PSA(L155)-LFA-3/ICAM-1/B7.1
Part	whole
Record UNII	7PLH7RM47T
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Rilimogene Glafolivec

Official Name

English

rilimogene glafolivec [INN]

Common Name

English

recombinant non-replicating fowlpox viral vector expressing a modified prostate specific antigen (PSA) plus three co-stimulatory molecules, lymphocyte associated function antigen-3 (LFA-3), intracellular adhesion molecule-1 (ICAM-1) and B7.1

Common Name

English

RILIMOGENE GLAFOLIVEC [WHO-DD]

Common Name

English

RILIMOGENE GLAFOLIVEC [USAN]

Common Name

English

PROSTVAC-F

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C2667

Created by admin on Sat Dec 16 19:46:00 GMT 2023 , Edited by admin on Sat Dec 16 19:46:00 GMT 2023

Code System Code Type Description

FDA UNII

7PLH7RM47T

Created by admin on Sat Dec 16 19:46:00 GMT 2023 , Edited by admin on Sat Dec 16 19:46:00 GMT 2023

PRIMARY

INN

9632

Created by admin on Sat Dec 16 19:46:00 GMT 2023 , Edited by admin on Sat Dec 16 19:46:00 GMT 2023

PRIMARY

CAS

1225283-42-0

Created by admin on Sat Dec 16 19:46:00 GMT 2023 , Edited by admin on Sat Dec 16 19:46:00 GMT 2023

PRIMARY

USAN

YY-130

Created by admin on Sat Dec 16 19:46:00 GMT 2023 , Edited by admin on Sat Dec 16 19:46:00 GMT 2023

PRIMARY

Related Record Type Details


					7PLH7RM47T

Rilimogene Glafolivec

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
VECTOR EXPRESSED PROTEIN					T-LYMPHOCYTE ACTIVATION ANTIGEN CD80	W6H7SY78HC
VECTOR EXPRESSED PROTEIN					Lymphocyte function-associated antigen 3	ULW3BA7J7W
VECTOR EXPRESSED PROTEIN					T-lymphocyte activation antigen CD80 preprotein	APN8654GMB
VECTOR EXPRESSED PROTEIN					Rilimogene galvacirepvec expressed prostate-specific antigen (I155L, N196Y)	SWH9LGX9PA
VECTOR EXPRESSED PROTEIN					Rilimogene galvacirepvec expressed intracellular adhesion molecule-1	E14H39HRH1