EFMOROCTOCOG ALFA

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

US Approved Rx (2014)

First approved in 2014

Approval Year

Substance Class	Protein Created by `admin` on `Mon Mar 31 21:33:13 GMT 2025` Edited by `admin` on `Mon Mar 31 21:33:13 GMT 2025`
Protein Sub Type
Sequence Type	COMPLETE
Record UNII	7PCM518YLR
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

EFMOROCTOCOG ALFA

Official Name

English

antihemophilic factor (recombinant), fc fusion protein

Preferred Name

English

ELOCTA

Brand Name

English

(1-743)-(1638-2332)-BLOOD-COAGULATION FACTOR VIII (SYNTHETIC HUMAN) FUSION PROTEIN WITH IMMUNOGLOBULIN G1 (SYNTHETIC HUMAN FC DOMAIN FRAGMENT), (1444-6'),(1447-9')-BIS(DISULFIDE) WITH IMMUNOGLOBULIN G1 (SYNTHETIC HUMAN FC DOMAIN FRAGMENT)

Common Name

English

EFRALOCTOCOG ALFA [JAN]

Common Name

English

Efmoroctocog alfa [WHO-DD]

Common Name

English

COAGULATION FACTOR VIII RECOMBINANT IMMUNOGLUBULIN G1 FUSION PROTEIN

Common Name

English

ELOCTATE

Brand Name

English

ANTIHEMOPHILIC FACTOR (RECOMBINANT, FC FUSION PROTEIN)

Common Name

English

efmoroctocog alfa [INN]

Common Name

English

Classification Tree Code System Code

FDA ORPHAN DRUG

321610

Created by admin on Mon Mar 31 21:33:13 GMT 2025 , Edited by admin on Mon Mar 31 21:33:13 GMT 2025

Code System Code Type Description

DAILYMED

7PCM518YLR

Created by admin on Mon Mar 31 21:33:13 GMT 2025 , Edited by admin on Mon Mar 31 21:33:13 GMT 2025

PRIMARY

NCI_THESAURUS

C167039

Created by admin on Mon Mar 31 21:33:13 GMT 2025 , Edited by admin on Mon Mar 31 21:33:13 GMT 2025

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SMS_ID

100000158419

Created by admin on Mon Mar 31 21:33:13 GMT 2025 , Edited by admin on Mon Mar 31 21:33:13 GMT 2025

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FDA UNII

7PCM518YLR

Created by admin on Mon Mar 31 21:33:13 GMT 2025 , Edited by admin on Mon Mar 31 21:33:13 GMT 2025

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WIKIPEDIA

Efmoroctocog alfa

Created by admin on Mon Mar 31 21:33:13 GMT 2025 , Edited by admin on Mon Mar 31 21:33:13 GMT 2025

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DRUG CENTRAL

5178

Created by admin on Mon Mar 31 21:33:13 GMT 2025 , Edited by admin on Mon Mar 31 21:33:13 GMT 2025

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DRUG BANK

DB11607

Created by admin on Mon Mar 31 21:33:13 GMT 2025 , Edited by admin on Mon Mar 31 21:33:13 GMT 2025

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EVMPD

SUB168409

Created by admin on Mon Mar 31 21:33:13 GMT 2025 , Edited by admin on Mon Mar 31 21:33:13 GMT 2025

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INN

9680

Created by admin on Mon Mar 31 21:33:13 GMT 2025 , Edited by admin on Mon Mar 31 21:33:13 GMT 2025

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CAS

1270012-79-7

Created by admin on Mon Mar 31 21:33:13 GMT 2025 , Edited by admin on Mon Mar 31 21:33:13 GMT 2025

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RXCUI

1543095

Created by admin on Mon Mar 31 21:33:13 GMT 2025 , Edited by admin on Mon Mar 31 21:33:13 GMT 2025

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From	To
1_153	1_179
1_248	1_329
1_528	1_554
1_630	1_711
1_938	1_964
1_1005	1_1009
1_1127	1_1275
1_1280	1_1432
1_1444	2_6
1_1447	2_9
1_1479	1_1539
1_1585	1_1643
2_41	2_101
2_147	2_205

Glycosylation Type

HUMAN

Glycosylation Link Type	Site
N	1_41
N	1_239
N	1_916
N	1_1224
N	1_1515
N	2_77

Related Record Type Details


					7PCM518YLR

EFMOROCTOCOG ALFA

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION	[1_346] [1_718] [1_719] [1_723] [1_770] [1_786]		Tyr		TYROSINE O-SULFATE	29166358BF

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL