IMCY-0098

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 18:27:25 GMT 2025` Edited by `admin` on `Wed Apr 02 18:27:25 GMT 2025`
Protein Type	PEPTIDE
Protein Sub Type
Sequence Origin	SYNTHETIC
Sequence Type	COMPLETE
Record UNII	7M9GZF9VTT
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

IMCY-0098

Common Name

English

H-His-Cys-Pro-Tyr-Cys-Ser-Leu-Gln-Pro-Leu-Ala-Leu-Glu-Gly-Ser-Leu-Gln-Lys-Arg-Gly-NH2

Preferred Name

English

L-histidyl-L-cysteinyl-L-prolyl-L-tyrosyl-L-cysteinyl-L-seryl-Lleucyl-L-glutaminyl-L-prolyl-L-leucyl-L-alanyl-L-leucyl-Lglutamylglycyl-L- seryl-L-leucyl-L-glutaminyl-L-lysyl-L-arginylglycinamide

Common Name

English

Code System Code Type Description

FDA UNII

7M9GZF9VTT

Created by admin on Wed Apr 02 18:27:25 GMT 2025 , Edited by admin on Wed Apr 02 18:27:25 GMT 2025

PRIMARY

SMS_ID

300000037269

Created by admin on Wed Apr 02 18:27:25 GMT 2025 , Edited by admin on Wed Apr 02 18:27:25 GMT 2025

PRIMARY

From	To
1_2	1_5

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					SD3HRQ5ABW

Cytolytic CD4 T-cell

TARGET -> ACTIVATOR

Comments:

Thioredox motif (CXXC) stimulates or activates cells

Amount:


					O2J76Y002M

HUMAN C-PEPTIDE

TARGET->TOLEROGEN

Comments:

Cytolytic CD4+ T cells eliminated autoreactive pathogenic T cells directed against this epitope and other epitopes presented on the same APC (bystander effect), thus protecting ?-cells from autoimmune attack. Peptide designed to bind MHCII.

Amount:

Related Record Type Details


					7M9GZF9VTT

IMCY-0098

ACTIVE MOIETY

Comments:

to prevent and suppress Type 1 Diabetes (T1D)

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION	[1_20]	N-TERMINUS	G		GLYCINAMIDE	4JDT453NWO

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL