Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C4H3ClN2O2 |
| Molecular Weight | 146.532 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
ClC1=CNC(=O)NC1=O
InChI
InChIKey=ZFTBZKVVGZNMJR-UHFFFAOYSA-N
InChI=1S/C4H3ClN2O2/c5-2-1-6-4(9)7-3(2)8/h1H,(H2,6,7,8,9)
| Molecular Formula | C4H3ClN2O2 |
| Molecular Weight | 146.532 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Interaction of monoclonal antibodies directed against bromodeoxyuridine with pyrimidine bases, nucleosides, and DNA. | 1986 Mar 1 |
|
| Structure-activity relationship of ligands of uracil phosphoribosyltransferase from Toxoplasma gondii. | 1994 Aug 17 |
|
| Synthesis of 5-chloro-1-(2,3-dideoxy-3-fluoro-beta-D-glycero-hex-2- enopyranose-4-ulosyl)uracil as potential anticancer/antiviral agent. | 2001 Apr-Jul |
|
| An improved resazurin-based cytotoxicity assay for hepatic cells. | 2002 |
|
| Detection and quantification of 5-chlorocytosine in DNA by stable isotope dilution and gas chromatography/negative ion chemical ionization/mass spectrometry. | 2002 Feb |
|
| Analytical and pharmacokinetic studies with 5-chloro-2'-deoxycytidine. | 2002 Nov 15 |
|
| Hydrophilic interaction liquid chromatography-APCI-mass spectrometry determination of 5-fluorouracil in plasma and tissues. | 2005 Jul 15 |
|
| Evaluation of novel one-electron reduction with metal in DNA. | 2006 |
|
| Myeloperoxidase generates 5-chlorouracil in human atherosclerotic tissue: a potential pathway for somatic mutagenesis by macrophages. | 2006 Feb 10 |
|
| [Clinical benefit of S-1 in metastatic breast cancer]. | 2006 Jun |
|
| Controlled delivery of 5-chlorouracil using poly(ortho esters) in filtering surgery for glaucoma. | 2008 Jul |
|
| Examination of hypochlorous acid-induced damage to cytosine residues in a CpG dinucleotide in DNA. | 2008 Jun |
|
| Significance of 5-fluorouracil-related enzyme activities in predicting sensitivity to 5-fluorouracil in bladder carcinoma. | 2009 Apr |
|
| Retrospective analysis of S-1 monotherapy in patients with metastatic colorectal cancer after failure to fluoropyrimidine and irinotecan or to fluoropyrimidine, irinotecan and oxaliplatin. | 2009 May |
|
| [Markers of chloric acid (I) in biological systems--identification and properties]. | 2010 |
|
| Characterization of a novel lymph node metastasis model from human colonic cancer and its preclinical use for comparison of anti-metastatic efficacy between oral S-1 and UFT/ LV. | 2010 Aug |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 00:42:09 UTC 2023
by
admin
on
Sat Dec 16 00:42:09 UTC 2023
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| Record UNII |
7LQ4V03RNY
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| Record Status |
Validated (UNII)
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| Record Version |
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1820-81-1
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15758
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217-339-7
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1279054
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7LQ4V03RNY
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60762
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28172
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DTXSID7075137
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| Related Record | Type | Details | ||
|---|---|---|---|---|
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PARENT -> IMPURITY |
USP Peak Value = 0.15%
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
|
