ISOFEZOLAC

Details

Stereochemistry	ACHIRAL
Molecular Formula	C23H18N2O2
Molecular Weight	354.4012
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OC(=O)CC1=C(C(=NN1C2=CC=CC=C2)C3=CC=CC=C3)C4=CC=CC=C4

InChI

InChIKey=LZRDDINFIHUVCX-UHFFFAOYSA-N

InChI=1S/C23H18N2O2/c26-21(27)16-20-22(17-10-4-1-5-11-17)23(18-12-6-2-7-13-18)24-25(20)19-14-8-3-9-15-19/h1-15H,16H2,(H,26,27)

HIDE SMILES / InChI

Molecular Formula	C23H18N2O2
Molecular Weight	354.4012
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: http://www.druglead.com/cds/Isofezolac.html | https://books.google.ru/books?id=j-3Cd_SWIksC&pg=PA319&lpg=PA319&dq=Isofezolac&source#v=onepage&q=Isofezolac&f=false

ISOFEZOLAC is a non-steroid anti-inflammatory drug, prostaglandin synthetase inhibitor. It is indicated for use in various forms of rheumatoid arthritis and osteoarthritis.

Originator

Approval Year

PubMed

Title	Date	PubMed
Effect of probenecid on isofezolac kinetics.	1985	4029250
The effect of antacid and aspirin on the bioavailability of isofezolac in man.	1984-09	6500763
Study of two new non-steroid anti-inflammatory drugs having a pyrazole structure (LM 22070 and LM 22102).	1979-04	112931

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:33:23 GMT 2025` Edited by `admin` on `Mon Mar 31 18:33:23 GMT 2025`
Record UNII	7K6U6T1360
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ISOFEZOLAC

Official Name

English

ISOFEZOLAC [MI]

Preferred Name

English

isofezolac [INN]

Common Name

English

1,3,4-TRIPHENYLPYRAZOLE-5-ACETIC ACID

Systematic Name

English

Isofezolac [WHO-DD]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C257