U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 13:40:39 GMT 2023
Edited
by admin
on Sat Dec 16 13:40:39 GMT 2023
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG1
Sequence Origin HUMANIZED MOUSE
Sequence Type COMPLETE
Record UNII
7K5O7P6QIU
Record Status Validated (UNII)
Record Version
  • Download
Related Record Type
Name Type Language
LONCASTUXIMAB TESIRINE
INN  
Official Name English
IMMUNOGLOBULIN G1, ANTI-(HUMAN CD19 ANTIGEN) (HUMAN-MUS MUSCULUS MONOCLONAL RB4V1.2 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL RB4V1.2 .KAPPA.-CHAIN, DIMER, BIS(THIOETHER) WITH N-(31-(2,5-DIHYDRO-2,5-DIOXO-1H-PYRROL-1-YL)-1,29-DIOXO-4,
Systematic Name English
loncastuximab tesirine [INN]
Common Name English
IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS B-LYMPHOCYTE ANTIGEN CD-19)CHIMERIC MONOCLONAL ANTIBODY CONJUGATED TO AN AVERAGE OF TWO MOLECULES OF TESIRINE.GAMMA.1 HEAVY CHAIN (1-449) (MUS MUSCULUS VH (IGHV1-69*02 (86%) (IGHD)-IGHJ4*01)) (8.8.13) (1-120) -
Systematic Name English
Loncastuximab tesirine [WHO-DD]
Common Name English
ADCT-402
Code English
LONCASTUXIMAB TESIRINE [USAN]
Common Name English
Classification Tree Code System Code
FDA ORPHAN DRUG 572816
Created by admin on Sat Dec 16 13:40:39 GMT 2023 , Edited by admin on Sat Dec 16 13:40:39 GMT 2023
FDA ORPHAN DRUG 572716
Created by admin on Sat Dec 16 13:40:39 GMT 2023 , Edited by admin on Sat Dec 16 13:40:39 GMT 2023
Code System Code Type Description
CAS
1879918-31-6
Created by admin on Sat Dec 16 13:40:39 GMT 2023 , Edited by admin on Sat Dec 16 13:40:39 GMT 2023
PRIMARY
NCI_THESAURUS
C125549
Created by admin on Sat Dec 16 13:40:39 GMT 2023 , Edited by admin on Sat Dec 16 13:40:39 GMT 2023
PRIMARY
USAN
FG-29
Created by admin on Sat Dec 16 13:40:40 GMT 2023 , Edited by admin on Sat Dec 16 13:40:40 GMT 2023
PRIMARY
DAILYMED
7K5O7P6QIU
Created by admin on Sat Dec 16 13:40:39 GMT 2023 , Edited by admin on Sat Dec 16 13:40:39 GMT 2023
PRIMARY
FDA UNII
7K5O7P6QIU
Created by admin on Sat Dec 16 13:40:39 GMT 2023 , Edited by admin on Sat Dec 16 13:40:39 GMT 2023
PRIMARY
WIKIPEDIA
Loncastuximab tesirine
Created by admin on Sat Dec 16 13:40:40 GMT 2023 , Edited by admin on Sat Dec 16 13:40:40 GMT 2023
PRIMARY
RXCUI
2540964
Created by admin on Sat Dec 16 13:40:39 GMT 2023 , Edited by admin on Sat Dec 16 13:40:39 GMT 2023
PRIMARY
INN
10586
Created by admin on Sat Dec 16 13:40:39 GMT 2023 , Edited by admin on Sat Dec 16 13:40:39 GMT 2023
PRIMARY
From To
1_22 1_96
1_147 1_203
1_264 1_324
1_370 1_428
2_22 2_96
2_147 2_203
2_264 2_324
2_370 2_428
1_223 3_211
1_229 2_229
1_232 2_223
2_232 4_211
3_23 3_87
3_131 3_191
4_23 4_87
4_131 4_191
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_300
N 2_300
Related Record Type Details
TARGET->CONJUGATED TOXIN
SUB_CONCEPT->SUBSTANCE
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL