U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Structurally Diverse
Created
by admin
on Sat Jun 26 16:56:14 UTC 2021
Edited
by admin
on Sat Jun 26 16:56:14 UTC 2021
Source Materials Class ORGANISM
Source Materials Type AUTOLOGOUS HUMAN
Source Materials State LIVE
Source Materials Parent
Part BLOOD
Fraction Material Type CELL
Fraction Name T-CELLS
Record UNII
7K2YOJ14X0
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
LISOCABTAGENE MARALEUCEL
USAN   INN  
Official Name English
LISOCABTAGENE MARALEUCEL [USAN]
Common Name English
JCAR-017
Code English
JCAR017
Code English
LISOCABTAGENE MARALEUCEL [INN]
Common Name English
LISOCABTAGENE MARALEUCEL [WHO-DD]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C129826
Created by admin on Sat Jun 26 16:56:14 UTC 2021 , Edited by admin on Sat Jun 26 16:56:14 UTC 2021
FDA ORPHAN DRUG 730920
Created by admin on Sat Jun 26 16:56:14 UTC 2021 , Edited by admin on Sat Jun 26 16:56:14 UTC 2021
FDA ORPHAN DRUG 644018
Created by admin on Sat Jun 26 16:56:14 UTC 2021 , Edited by admin on Sat Jun 26 16:56:14 UTC 2021
FDA ORPHAN DRUG 516115
Created by admin on Sat Jun 26 16:56:14 UTC 2021 , Edited by admin on Sat Jun 26 16:56:14 UTC 2021
FDA ORPHAN DRUG 600517
Created by admin on Sat Jun 26 16:56:14 UTC 2021 , Edited by admin on Sat Jun 26 16:56:14 UTC 2021
NCI_THESAURUS C28681
Created by admin on Sat Jun 26 16:56:14 UTC 2021 , Edited by admin on Sat Jun 26 16:56:14 UTC 2021
EU-Orphan Drug EU/3/18/2099
Created by admin on Sat Jun 26 16:56:14 UTC 2021 , Edited by admin on Sat Jun 26 16:56:14 UTC 2021
NCI_THESAURUS C137999
Created by admin on Sat Jun 26 16:56:14 UTC 2021 , Edited by admin on Sat Jun 26 16:56:14 UTC 2021
Code System Code Type Description
INN
10805
Created by admin on Sat Jun 26 16:56:14 UTC 2021 , Edited by admin on Sat Jun 26 16:56:14 UTC 2021
PRIMARY
FDA UNII
7K2YOJ14X0
Created by admin on Sat Jun 26 16:56:14 UTC 2021 , Edited by admin on Sat Jun 26 16:56:14 UTC 2021
PRIMARY
NCI_THESAURUS
C125192
Created by admin on Sat Jun 26 16:56:14 UTC 2021 , Edited by admin on Sat Jun 26 16:56:14 UTC 2021
PRIMARY
Related Record Type Details
ACTIVE MOIETY

Agent Modifications

Modification Process Modification Role Modification Type Amount Fragment Name Fragment ID
TRANSDUCTION OF EXPRESSION VECTOR RECEPTOR EXPRESSION RETROVIRAL TRANSFECTION LISOCABTAGENE MARALEUCEL LENTIVIRUS VECTOR TO1TNB1HUL

Structural Modifications

Modification Type Location Site Location Type Residue Modified Extent Fragment Name Fragment Approval
INSERTED GENE EXPRESSION VECTOR LISOCABTAGENE MARALEUCEL TRANSGENE INSERT 939TQL8M8R
VECTOR EXPRESSED PROTEIN UNSPECIFIED SUBSTANCE
1cd64bba
(not in database)
CAR-T RECEPTOR UNSPECIFIED SUBSTANCE
d9371313
(not in database)
Name Property Type Amount Referenced Substance Defining Parameters References
CD4/CD8 RATIO IMMUNOLOGICAL