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Approval Year

Unknown
149124
Substance Class Protein
Created
by admin
on Wed Apr 02 07:30:03 GMT 2025
Edited
by admin
on Wed Apr 02 07:30:03 GMT 2025
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG1
Sequence Origin HUMANIZED MOUSE
Sequence Type COMPLETE
Record UNII
7JNY4KV3NK
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ociperlimab [INN]
Preferred Name English
OCIPERLIMAB
USAN   INN  
Official Name English
IMMUNOGLOBULIN G1, ANTI-(HUMAN RECEPTOR TIGIT) (HUMAN-MUS MUSCULUS MONOCLONAL BGB-A1217 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL BGB-A1217 .KAPPA.-CHAIN, DIMER
Common Name English
OCIPERLIMAB [USAN]
Common Name English
IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS TIGIT (T-CELL IMMUNORECEPTOR WITH IG DOMAIN AND ITIM, V-SET IG MEMBER 9, VSIG9, V-SET AND TRANSMEMBRANE MEMBER 3, VSTM3)), HUMANIZED MONOCLONAL ANTIBODY; GAMMA1 HEAVY CHAIN HUMANIZED (1-449) (VH (HOMO SAPIENS I
Common Name English
BGB-A1217
Code English
IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS TIGIT (T-CELL IMMUNORECEPTOR WITH IG DOMAIN AND ITIM, V-SET IG MEMBER 9, VSIG9, V-SET AND TRANSMEMBRANE MEMBER 3, VSTM3)), HUMANIZED MONOCLONAL ANTIBODY (OCIPERLIMAB)
Common Name English
Ociperlimab [WHO-DD]
Common Name English
BGBA-1217
Code English
BGBA1217
Code English
Code System Code Type Description
NCI_THESAURUS
C170906
Created by admin on Wed Apr 02 07:30:03 GMT 2025 , Edited by admin on Wed Apr 02 07:30:03 GMT 2025
PRIMARY
CAS
2342597-93-5
Created by admin on Wed Apr 02 07:30:03 GMT 2025 , Edited by admin on Wed Apr 02 07:30:03 GMT 2025
PRIMARY
INN
11452
Created by admin on Wed Apr 02 07:30:03 GMT 2025 , Edited by admin on Wed Apr 02 07:30:03 GMT 2025
PRIMARY
FDA UNII
7JNY4KV3NK
Created by admin on Wed Apr 02 07:30:03 GMT 2025 , Edited by admin on Wed Apr 02 07:30:03 GMT 2025
PRIMARY
SMS_ID
300000026757
Created by admin on Wed Apr 02 07:30:03 GMT 2025 , Edited by admin on Wed Apr 02 07:30:03 GMT 2025
PRIMARY
USAN
JK-219
Created by admin on Wed Apr 02 07:30:03 GMT 2025 , Edited by admin on Wed Apr 02 07:30:03 GMT 2025
PRIMARY
From To
4_134 4_194
4_23 4_88
3_134 3_194
3_23 3_88
2_369 2_427
2_263 2_323
2_222 4_214
2_146 2_202
2_22 2_96
1_369 1_427
1_263 1_323
1_231 2_231
1_228 2_228
1_222 3_214
1_146 1_202
1_22 1_96
Glycosylation Link Type Site
N 1_299
N 2_299
Related Record Type Details
T-CELL IMMUNORECEPTOR WITH IG AND ITIM DOMAINS
TARGET -> INHIBITOR
Related Record Type Details
OCIPERLIMAB
ACTIVE MOIETY

Structural Modifications

Modification Type Location Site Location Type Residue Modified Extent Fragment Name Fragment Approval
AMINO ACID REMOVAL [1_449] [2_449] C-TERMINUS LYSINE K3Z4F929H6
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
NIH
NCATS
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