U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C14H21ClN2O2
Molecular Weight 284.782
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 1
Charge 0

SHOW SMILES / InChI
Structure of CLOVOXAMINE

SMILES

COCCCC\C(C1=CC=C(Cl)C=C1)=N/OCCN

InChI

InChIKey=XXPVSQRPGBUFKM-SAPNQHFASA-N
InChI=1S/C14H21ClN2O2/c1-18-10-3-2-4-14(17-19-11-9-16)12-5-7-13(15)8-6-12/h5-8H,2-4,9-11,16H2,1H3/b17-14+

HIDE SMILES / InChI

Molecular Formula C14H21ClN2O2
Molecular Weight 284.782
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 1
Optical Activity NONE

Clovoxamine is an antidepressant and anxiolytic drug, acting as a serotonin and norepinephrine reuptake inhibitor. The drug was investigated in the double-blind clinical trials for the treatment of anxiety neurosis, where it was compared with diazepam, and found to have comparable efficacy but higher drop out rate.

Approval Year

Patents
Substance Class Chemical
Created
by admin
on Fri Dec 15 17:13:40 GMT 2023
Edited
by admin
on Fri Dec 15 17:13:40 GMT 2023
Record UNII
7I22J7RY2A
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
CLOVOXAMINE
INN   MART.  
INN  
Official Name English
clovoxamine [INN]
Common Name English
4'-CHLORO-5-METHOXYVALEROPHENONE (E)-O-(2-AMINOETHYL)OXIME
Systematic Name English
CLOVOXAMINE [MART.]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C265
Created by admin on Fri Dec 15 17:13:40 GMT 2023 , Edited by admin on Fri Dec 15 17:13:40 GMT 2023
Code System Code Type Description
CHEBI
36813
Created by admin on Fri Dec 15 17:13:40 GMT 2023 , Edited by admin on Fri Dec 15 17:13:40 GMT 2023
PRIMARY
INN
3880
Created by admin on Fri Dec 15 17:13:40 GMT 2023 , Edited by admin on Fri Dec 15 17:13:40 GMT 2023
PRIMARY
MESH
C020724
Created by admin on Fri Dec 15 17:13:40 GMT 2023 , Edited by admin on Fri Dec 15 17:13:40 GMT 2023
PRIMARY
SMS_ID
100000084035
Created by admin on Fri Dec 15 17:13:40 GMT 2023 , Edited by admin on Fri Dec 15 17:13:40 GMT 2023
PRIMARY
CAS
54739-19-4
Created by admin on Fri Dec 15 17:13:40 GMT 2023 , Edited by admin on Fri Dec 15 17:13:40 GMT 2023
PRIMARY
NCI_THESAURUS
C78003
Created by admin on Fri Dec 15 17:13:40 GMT 2023 , Edited by admin on Fri Dec 15 17:13:40 GMT 2023
PRIMARY
PUBCHEM
6335903
Created by admin on Fri Dec 15 17:13:40 GMT 2023 , Edited by admin on Fri Dec 15 17:13:40 GMT 2023
PRIMARY
EPA CompTox
DTXSID501023903
Created by admin on Fri Dec 15 17:13:40 GMT 2023 , Edited by admin on Fri Dec 15 17:13:40 GMT 2023
PRIMARY
EVMPD
SUB06778MIG
Created by admin on Fri Dec 15 17:13:40 GMT 2023 , Edited by admin on Fri Dec 15 17:13:40 GMT 2023
PRIMARY
WIKIPEDIA
CLOVOXAMINE
Created by admin on Fri Dec 15 17:13:40 GMT 2023 , Edited by admin on Fri Dec 15 17:13:40 GMT 2023
PRIMARY
FDA UNII
7I22J7RY2A
Created by admin on Fri Dec 15 17:13:40 GMT 2023 , Edited by admin on Fri Dec 15 17:13:40 GMT 2023
PRIMARY
ChEMBL
CHEMBL2105603
Created by admin on Fri Dec 15 17:13:40 GMT 2023 , Edited by admin on Fri Dec 15 17:13:40 GMT 2023
PRIMARY
Related Record Type Details
SALT/SOLVATE -> PARENT
Related Record Type Details
ACTIVE MOIETY