U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class
Concept
Record UNII
7EM2VXC85Q
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
NBL-015
Code English
NBL-015 (ANTI-CLAUDIN18.2 MAB)
Common Name English
Fully human monoclonal IgG1 antibody against the type 2 isoform of human Claudin 18 protein (Claudin 18.2).
Common Name English
Classification Tree Code System Code
FDA ORPHAN DRUG 810021
Created by admin on Sat Dec 16 18:23:34 GMT 2023 , Edited by admin on Sat Dec 16 18:23:34 GMT 2023
FDA ORPHAN DRUG 784020
Created by admin on Sat Dec 16 18:23:34 GMT 2023 , Edited by admin on Sat Dec 16 18:23:34 GMT 2023
Code System Code Type Description
FDA UNII
7EM2VXC85Q
Created by admin on Sat Dec 16 18:23:34 GMT 2023 , Edited by admin on Sat Dec 16 18:23:34 GMT 2023
PRIMARY
This is a non-substance concept
Related Record Type Details
ACTIVE MOIETY
Upon binding to Claudin18.2-expressing tumor cells, NBL-015 mediates antibody-dependent cellular toxicity (ADCC) in the presence of NK cells
This is a non-substance concept