Details
Stereochemistry | ABSOLUTE |
Molecular Formula | C20H32O2 |
Molecular Weight | 304.4669 |
Optical Activity | UNSPECIFIED |
Defined Stereocenters | 8 / 8 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
[H][C@@]12CC[C@H](O)[C@@]1(C)CC[C@@]3([H])[C@@]2([H])CC[C@@]4([H])CC(=O)[C@H](C)C[C@]34C
InChI
InChIKey=IKXILDNPCZPPRV-RFMGOVQKSA-N
InChI=1S/C20H32O2/c1-12-11-20(3)13(10-17(12)21)4-5-14-15-6-7-18(22)19(15,2)9-8-16(14)20/h12-16,18,22H,4-11H2,1-3H3/t12-,13+,14+,15+,16+,18+,19+,20+/m1/s1
Molecular Formula | C20H32O2 |
Molecular Weight | 304.4669 |
Charge | 0 |
Count |
|
Stereochemistry | ABSOLUTE |
Additional Stereochemistry | No |
Defined Stereocenters | 8 / 8 |
E/Z Centers | 0 |
Optical Activity | UNSPECIFIED |
DescriptionSources: http://steroid.es/drostanolone.html
Sources: http://steroid.es/drostanolone.html
Dromostanolone Propionate (known by the brand names Masteron and Drolban) was invented by Syntex in 1959. About 10 years later it was released on the American market by Lilly as brand name Drolban. The drug was first approved in the USA for use as a treatment of female breast cancer. However, the profile of side-effects included pronouncement of male characteristics in women and when more effective breast cancer treatments came to market drostanolone was gradually phased out. No longer used clinically dromostanolone propionate became very popular in the bodybuilding community. Today dromostanolone propionate remains on the list of approved medications, but it is not being manufactured or sold by pharmaceutical companies. It is still produced illegally by underground labs for use in the bodybuilding community.
Originator
Approval Year
Targets
Primary Target | Pharmacology | Condition | Potency |
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Target ID: CHEMBL1871 Sources: https://www.ncbi.nlm.nih.gov/pubmed/3758193 |
Conditions
Condition | Modality | Targets | Highest Phase | Product |
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Primary | Drolban Approved UseUnknown |
Doses
Dose | Population | Adverse events |
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100 mg 4 times / day multiple, oral Dose: 100 mg, 4 times / day Route: oral Route: multiple Dose: 100 mg, 4 times / day Sources: |
unhealthy, adult n = 9 Health Status: unhealthy Age Group: adult Sex: M+F Population Size: 9 Sources: |
Disc. AE: Hypertriglyceridemia... AEs leading to discontinuation/dose reduction: Hypertriglyceridemia (5 patients) Sources: |
AEs
AE | Significance | Dose | Population |
---|---|---|---|
Hypertriglyceridemia | 5 patients Disc. AE |
100 mg 4 times / day multiple, oral Dose: 100 mg, 4 times / day Route: oral Route: multiple Dose: 100 mg, 4 times / day Sources: |
unhealthy, adult n = 9 Health Status: unhealthy Age Group: adult Sex: M+F Population Size: 9 Sources: |
PubMed
Title | Date | PubMed |
---|---|---|
Myocardial infarction with intracoronary thrombus induced by anabolic steroids. | 2004 Dec |
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Intracerebroventricular self-administration of commonly abused anabolic-androgenic steroids in male hamsters (Mesocricetus auratus): nandrolone, drostanolone, oxymetholone, and stanozolol. | 2005 Jun |
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6alpha-Methylandrostenedione: gas chromatographic mass spectrometric detection in doping control. | 2008 |
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Systematic review of the clinical effect of glucocorticoids on nonhematologic malignancy. | 2008 Mar 28 |
|
Identification of drostanolone and 17-methyldrostanolone metabolites produced by cryopreserved human hepatocytes. | 2009 Mar |
Sample Use Guides
In Vivo Use Guide
Sources: http://steroid.es/drostanolone.html
Unknown
Route of Administration:
Intramuscular
Substance Class |
Chemical
Created
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admin
on
Edited
Fri Dec 15 16:14:38 GMT 2023
by
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on
Fri Dec 15 16:14:38 GMT 2023
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Record UNII |
7DR7H00HDT
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Record Status |
Validated (UNII)
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Record Version |
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NCI_THESAURUS |
C243
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NCI_THESAURUS |
C2360
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WIKIPEDIA |
Designer-drugs-Drostanolone
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DEA NO. |
4000
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Drostanolone
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m4767
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C1076
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7DR7H00HDT
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DTXSID6022971
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3319
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23678
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6011
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C100263
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DB00858
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SUB06414MIG
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1159
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100000081008
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34838
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58-19-5
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CHEMBL1201048
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200-367-9
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Related Record | Type | Details | ||
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ACTIVE MOIETY |