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Details

Stereochemistry RACEMIC
Molecular Formula C10H15N
Molecular Weight 149.2328
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PHENPROMETHAMINE

SMILES

CNCC(C)C1=CC=CC=C1

InChI

InChIKey=AUFSOOYCQYDGES-UHFFFAOYSA-N
InChI=1S/C10H15N/c1-9(8-11-2)10-6-4-3-5-7-10/h3-7,9,11H,8H2,1-2H3

HIDE SMILES / InChI
Molecular Formula C10H15N
Molecular Weight 149.2328
Charge 0
Count
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

Description

Phenpromethamine is an adrenergic agent. Phenpromethamine was used as vasodilator agent. It is a stimulant which is banned in sport. It is available in supplements which are sold as fat burners or pre-workout boosters. Phenpromethamine is a potent CYP2D6 inhibitor.

Approval Year

1943
64
Overview

Overview

CYP3A4CYP2C9CYP2D6hERG
inhibitor
1587
inhibitor
1852

OverviewOther

Other InhibitorOther SubstrateOther Inducer
Drug as perpetrator​

Drug as perpetrator​

TargetModalityActivityMetaboliteClinical evidence
CYP3A4
1925
 weak [Inhibition 100 uM]
CYP2D6
1891
 yes [IC50 76.6 uM]
Sourcing

Sourcing

Vendor/AggregatorIDURL
3B Scientific (Wuhan) Corp
3B3-032262
http://www.3bsc.com/index/pro_info.php?id=53526
AA Blocks
AA00GVWZ
http://www.aablocks.com/goods/Goods/detail?id=AA00GVWZ
AHH Chemical co.,ltd
MT-54171
http://www.ahhchemical.com/product/MT-54171.html
Acadechem
ACDR-055826
http://acadechemical.com/product/68234
Angene
AGN-PC-0W3HQ7
http://www.angenechemical.com/productshow/AGN-PC-0W3HQ7.html
Aurora Fine Chemicals LLC
A00.513.754
http://online.aurorafinechemicals.com/info?ID=A00.513.754
Aurora Fine Chemicals LLC
K00.817.613
http://online.aurorafinechemicals.com/info?ID=K00.817.613
Aurum Pharmatech LLC
T7102
http://www.Aurumpharmatech.com/Product/ProductDetails/T7102
Chemspace
CSSB00000188365
https://chem-space.com/CSSB00000188365
Clearsynth
CS-M-22214
https://www.clearsynth.com/en/CSM22214.html
Enamine
Z57797325
https://www.enaminestore.com/catalog/Z57797325
Matrix Scientific
33297
https://www.matrixscientific.com/033297.html
Oakwood
58699
http://www.oakwoodchemical.com/ProductsList.aspx?CategoryID=-2&txtSearch=48018&ExtHyperLink=1
Sigma-Aldrich
CDS011312_ALDRICH
https://www.sigmaaldrich.com/catalog/product/aldrich/cds011312?utm_source=pubchem&utm_campaign=pubchem_2017&utm_medium=referral
Smolecule
S602184
https://www.smolecule.com/products/s602184
THE BioTek
bt-289328
https://www.thebiotek.com/product/others/bt-289328
Vitas-M Laboratory
BBL000279
http://www.request.vitasmlab.biz/index.php?option=com_search_stk&Itemid=22&stk=BBL000279&?utm_source=pubchem&utm_medium=p_search_link&utm_campaign=pubchem_search&utm_content=pubchem_slink
mcule
MCULE-5892396720
https://mcule.com/MCULE-5892396720/
PubMed

PubMed

TitleDatePubMed
Cytochrome P450 2D6 and 3A4 enzyme inhibition by amine stimulants in dietary supplements.
2016 Mar-Apr
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:21:53 UTC 2023
Edited
by admin
on Fri Dec 15 15:21:53 UTC 2023
Record UNII
7D4542I59V
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
PHENPROMETHAMINE
INN   MART.  
INN  
Official Name English
N-METHYL-2-PHENYLPROPYLAMINE
Systematic Name English
PHENETHYLAMINE, N,.BETA.-DIMETHYL-
Systematic Name English
BENZENEETHANAMINE, N,.BETA.-DIMETHYL-
Systematic Name English
PHENPROMETHAMINE [MART.]
Common Name English
phenpromethamine [INN]
Common Name English
(±)-1-METHYLAMINO-2-PHENYLPROPANE
Systematic Name English
1-METHYLAMINO-2-METHYL-2-PHENYLETHANE
Systematic Name English
DL-N-METHYL-2-PHENYLPROPYLAMINE
Common Name English
1-METHYLAMINO-2-PHENYLPROPANE
Systematic Name English
DL-N,.BETA.-DIMETHYLBENZENEETHANAMINE
Common Name English
PHENYLPROPYLMETHYLAMINE [MI]
Common Name English
VONEDRINE
Brand Name English
N,.BETA.-DIMETHYLBENZENEETHANAMINE
Systematic Name English
N,.BETA.-DIMETHYLPHENETHYLAMINE
Systematic Name English
Code System Code Type Description
FDA UNII
7D4542I59V
Created by admin on Fri Dec 15 15:21:53 UTC 2023 , Edited by admin on Fri Dec 15 15:21:53 UTC 2023
PRIMARY
INN
139
Created by admin on Fri Dec 15 15:21:53 UTC 2023 , Edited by admin on Fri Dec 15 15:21:53 UTC 2023
PRIMARY
PUBCHEM
22276
Created by admin on Fri Dec 15 15:21:53 UTC 2023 , Edited by admin on Fri Dec 15 15:21:53 UTC 2023
PRIMARY
WIKIPEDIA
PHENPROMETHAMINE
Created by admin on Fri Dec 15 15:21:53 UTC 2023 , Edited by admin on Fri Dec 15 15:21:53 UTC 2023
PRIMARY
SMS_ID
100000082242
Created by admin on Fri Dec 15 15:21:53 UTC 2023 , Edited by admin on Fri Dec 15 15:21:53 UTC 2023
PRIMARY
MERCK INDEX
m8688
Created by admin on Fri Dec 15 15:21:53 UTC 2023 , Edited by admin on Fri Dec 15 15:21:53 UTC 2023
PRIMARY Merck Index
NCI_THESAURUS
C167019
Created by admin on Fri Dec 15 15:21:53 UTC 2023 , Edited by admin on Fri Dec 15 15:21:53 UTC 2023
PRIMARY
CAS
93-88-9
Created by admin on Fri Dec 15 15:21:53 UTC 2023 , Edited by admin on Fri Dec 15 15:21:53 UTC 2023
PRIMARY
EPA CompTox
DTXSID20861690
Created by admin on Fri Dec 15 15:21:53 UTC 2023 , Edited by admin on Fri Dec 15 15:21:53 UTC 2023
PRIMARY
EVMPD
SUB09782MIG
Created by admin on Fri Dec 15 15:21:53 UTC 2023 , Edited by admin on Fri Dec 15 15:21:53 UTC 2023
PRIMARY
CAS
6152-73-4
Created by admin on Fri Dec 15 15:21:53 UTC 2023 , Edited by admin on Fri Dec 15 15:21:53 UTC 2023
SUPERSEDED
DRUG CENTRAL
3461
Created by admin on Fri Dec 15 15:21:53 UTC 2023 , Edited by admin on Fri Dec 15 15:21:53 UTC 2023
PRIMARY
ChEMBL
CHEMBL1622886
Created by admin on Fri Dec 15 15:21:53 UTC 2023 , Edited by admin on Fri Dec 15 15:21:53 UTC 2023
PRIMARY
Related Record Type Details
Structure of PHENPROMETHAMINE HYDROCHLORIDE
SALT/SOLVATE -> PARENT
Related Record Type Details
Structure of PHENPROMETHAMINE
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