FEPRAZONE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C20H20N2O2
Molecular Weight	320.385
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of FEPRAZONE

Structure Search

SMILES

CC(C)=CCC1C(=O)N(N(C1=O)C2=CC=CC=C2)C3=CC=CC=C3

InChI

InChIKey=RBBWCVQDXDFISW-UHFFFAOYSA-N

InChI=1S/C20H20N2O2/c1-15(2)13-14-18-19(23)21(16-9-5-3-6-10-16)22(20(18)24)17-11-7-4-8-12-17/h3-13,18H,14H2,1-2H3

HIDE SMILES / InChI

Molecular Formula	C20H20N2O2
Molecular Weight	320.385
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: http://www.ncbi.nlm.nih.gov/pubmed/1094965
Curator's Comment: description was created based on several sources, including, https://www.jstage.jst.go.jp/article/cpb1958/34/1/34_1_214/_pdf

Feprazone is an anti-inflammatory compound developed for the treatment of such conditions as osteoarthritis, rheumatoid arthritis, rheumatic fever and gouty arthritis. The drug was tested in phase III of clinical trials, however its further faith is unknown.

Originator

Approval Year

Conditions

Conditions

Condition	Modality	Targets	Highest Phase	Product
Rheumatoid arthritis 316 Sources: http://www.ncbi.nlm.nih.gov/pubmed/1094965	Palliative		Phase III 656	Unknown Approved Use Unknown
Osteoarthritis 157 Sources: http://en.cnki.com.cn/Article_en/CJFDTOTAL-XYYL806.006.htm	Palliative		Phase III 656	Unknown Approved Use Unknown
Rheumatic fever 6 Sources: http://en.cnki.com.cn/Article_en/CJFDTOTAL-XYYL806.006.htm	Palliative		Phase III 656	Unknown Approved Use Unknown
Gouty arthritis 4 Sources: http://en.cnki.com.cn/Article_en/CJFDTOTAL-XYYL806.006.htm	Palliative		Phase III 656	Unknown Approved Use Unknown

PubMed

PubMed

Title	Date	PubMed
Retrospective analysis of drug-induced urticaria and angioedema: a survey of 2287 patients.	2001 Nov	11792017

Patents

Patents

Sample Use Guides

In Vivo Use Guide

150 mg four times daily.

Route of Administration: Oral

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:36:55 GMT 2023` Edited by `admin` on `Fri Dec 15 16:36:55 GMT 2023`
Record UNII	7BVX6J0CGR
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

FEPRAZONE

Official Name

English

4-(3-METHYL-2-BUTENYL)-1,2-DIPHENYL-3,5-PYRAZOLIDINEDIONE

Systematic Name

English

FEPRAZONE [JAN]

Common Name

English

FEPRAZONE [MART.]

Common Name

English

DA 2370

Code

English

feprazone [INN]

Common Name

English

DA-2370

Code

English

Feprazone [WHO-DD]

Common Name

English

FEPRAZONE [MI]

Common Name

English

Classification Tree Code System Code

WHO-ATC

M01AX18

Created by admin on Fri Dec 15 16:36:55 GMT 2023 , Edited by admin on Fri Dec 15 16:36:55 GMT 2023

NCI_THESAURUS

C1323

Created by admin on Fri Dec 15 16:36:55 GMT 2023 , Edited by admin on Fri Dec 15 16:36:55 GMT 2023

WHO-ATC

M02AA16

Created by admin on Fri Dec 15 16:36:55 GMT 2023 , Edited by admin on Fri Dec 15 16:36:55 GMT 2023

WHO-VATC

QM01AX18

Created by admin on Fri Dec 15 16:36:55 GMT 2023 , Edited by admin on Fri Dec 15 16:36:55 GMT 2023

WHO-VATC

QM01AX68

Created by admin on Fri Dec 15 16:36:55 GMT 2023 , Edited by admin on Fri Dec 15 16:36:55 GMT 2023

WHO-VATC

QM02AA16

Created by admin on Fri Dec 15 16:36:55 GMT 2023 , Edited by admin on Fri Dec 15 16:36:55 GMT 2023

WHO-ATC

M01AX68

Created by admin on Fri Dec 15 16:36:55 GMT 2023 , Edited by admin on Fri Dec 15 16:36:55 GMT 2023

Code System Code Type Description

DRUG BANK

DB13364

Created by admin on Fri Dec 15 16:36:55 GMT 2023 , Edited by admin on Fri Dec 15 16:36:55 GMT 2023

PRIMARY

MESH

D011298

Created by admin on Fri Dec 15 16:36:55 GMT 2023 , Edited by admin on Fri Dec 15 16:36:55 GMT 2023

PRIMARY

RXCUI

8673

Created by admin on Fri Dec 15 16:36:55 GMT 2023 , Edited by admin on Fri Dec 15 16:36:55 GMT 2023

PRIMARY

RxNorm

SMS_ID

100000080977

Created by admin on Fri Dec 15 16:36:55 GMT 2023 , Edited by admin on Fri Dec 15 16:36:55 GMT 2023

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WIKIPEDIA

Feprazone

Created by admin on Fri Dec 15 16:36:55 GMT 2023 , Edited by admin on Fri Dec 15 16:36:55 GMT 2023

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MERCK INDEX

m5309

Created by admin on Fri Dec 15 16:36:55 GMT 2023 , Edited by admin on Fri Dec 15 16:36:55 GMT 2023

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Merck Index

PUBCHEM

35455

Created by admin on Fri Dec 15 16:36:55 GMT 2023 , Edited by admin on Fri Dec 15 16:36:55 GMT 2023

PRIMARY

ECHA (EC/EINECS)

250-324-3

Created by admin on Fri Dec 15 16:36:55 GMT 2023 , Edited by admin on Fri Dec 15 16:36:55 GMT 2023

PRIMARY

FDA UNII

7BVX6J0CGR

Created by admin on Fri Dec 15 16:36:55 GMT 2023 , Edited by admin on Fri Dec 15 16:36:55 GMT 2023

PRIMARY

EVMPD

SUB07607MIG

Created by admin on Fri Dec 15 16:36:55 GMT 2023 , Edited by admin on Fri Dec 15 16:36:55 GMT 2023

PRIMARY

EPA CompTox

DTXSID3023051

Created by admin on Fri Dec 15 16:36:55 GMT 2023 , Edited by admin on Fri Dec 15 16:36:55 GMT 2023

PRIMARY

CAS

30748-29-9

Created by admin on Fri Dec 15 16:36:55 GMT 2023 , Edited by admin on Fri Dec 15 16:36:55 GMT 2023

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NCI_THESAURUS

C65675

Created by admin on Fri Dec 15 16:36:55 GMT 2023 , Edited by admin on Fri Dec 15 16:36:55 GMT 2023

PRIMARY

INN

3441

Created by admin on Fri Dec 15 16:36:55 GMT 2023 , Edited by admin on Fri Dec 15 16:36:55 GMT 2023

PRIMARY

ChEMBL

CHEMBL1452696

Created by admin on Fri Dec 15 16:36:55 GMT 2023 , Edited by admin on Fri Dec 15 16:36:55 GMT 2023

PRIMARY

DRUG CENTRAL

1169

Created by admin on Fri Dec 15 16:36:55 GMT 2023 , Edited by admin on Fri Dec 15 16:36:55 GMT 2023

PRIMARY

Related Record Type Details


					7BVX6J0CGR

FEPRAZONE

ACTIVE MOIETY