| Stereochemistry | RACEMIC |
| Molecular Formula | C10H14O3 |
| Molecular Weight | 182.2164 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC1=C(OCC(O)CO)C=CC=C1
InChI
InChIKey=JWDYCNIAQWPBHD-UHFFFAOYSA-N
InChI=1S/C10H14O3/c1-8-4-2-3-5-10(8)13-7-9(12)6-11/h2-5,9,11-12H,6-7H2,1H3
| Molecular Formula | C10H14O3 |
| Molecular Weight | 182.2164 |
| Charge | 0 |
| Count |
MOL RATIO
1 MOL RATIO (average) |
| Stereochemistry | RACEMIC |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Optical Activity | ( + / - ) |
Mephenesin is a centrally acting muscle relaxant. This medication is prescribed for muscle spasm. It can be used as an antidote for strychnine poisoning. Most common side effects are: lassitude, drowsiness, weakness, loss of appetite, nausea and vomiting, hypersensitivity reactions. Its clinical usefulness is considered to be limited by its brief duration of action.
CNS Activity
Originator
Approval Year
Doses
AEs
Sourcing
PubMed
Patents
Sample Use Guides
Oral: 1 to 2 tablets per dose (500 - 1000 mg), 3 times daily
Topical: 2 to 3 times a day with area messages of about ten minutes (duration - 5 days).
Route of Administration:
Other
Mephenesin is oxidatively metabolized in vitro 'by rat and mouse liver slices to 3- (o-tolyloxy)lactic acid. The uMoles of mephenesin metabolized per gram of fresh tissue was apparently a linear relationship with time up to 60 minutes. The maximum percent of substrate oxidized occurred between 1 500- 2000 ug.
