PERADOXIME

Details

Stereochemistry	RACEMIC
Molecular Formula	C22H29N3O4
Molecular Weight	399.4834
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

COC1=CC(C=NOCC(O)CN2CCN(CC2)C3=CC=CC=C3OC)=CC=C1

InChI

InChIKey=QSOFMSXQETVQGE-HAHDFKILSA-N

InChI=1S/C22H29N3O4/c1-27-20-7-5-6-18(14-20)15-23-29-17-19(26)16-24-10-12-25(13-11-24)21-8-3-4-9-22(21)28-2/h3-9,14-15,19,26H,10-13,16-17H2,1-2H3/b23-15-

HIDE SMILES / InChI

Molecular Formula	C22H29N3O4
Molecular Weight	399.4834
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	1
Optical Activity	( + / - )

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/7333331 | Elks, J. (2014) The Dictionary of Drugs: Chemical Data, page 951, retrieved from: https://books.google.ru/books?id=0vXTBwAAQBAJ

Peradoxime is an antihypertensive agent. In normal animals, 37-48% of the radioactivity from an oral dose of labeled peradoxime or parenteral dose was excreted in the urine, and 48-50% in the feces. Biliary and urinary metabolites of peradoxime were principally found as conjugates with glucuronic acid.

Approval Year

PubMed

Title	Date	PubMed

Sample Use Guides

In Vivo Use Guide

Single dose - 2 mg/kg of body weight

Route of Administration: Oral

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:40:01 GMT 2023` Edited by `admin` on `Fri Dec 15 15:40:01 GMT 2023`
Record UNII	7A977PW795
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

PERADOXIME

Official Name

English

peradoxime [INN]

Common Name

English

M-ANISALDEHYDE O-(2-HYDROXY-3-(4-(O-METHOXYPHENYL)-1-PIPERAZINYL)PROPYL) OXIME

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C241