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Details

Stereochemistry ACHIRAL
Molecular Formula C11H12N2O.C2H3Cl3O2
Molecular Weight 353.6291
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CHLORAL HYDRATE ANTIPYRINE

SMILES

Cc1cc(=O)n(-c2ccccc2)n1C.C(C(Cl)(Cl)Cl)(O)O

InChI

InChIKey=MIMVDBNKZRBPLZ-UHFFFAOYSA-N
InChI=1S/C11H12N2O.C2H3Cl3O2/c1-9-8-11(14)13(12(9)2)10-6-4-3-5-7-10;3-2(4,5)1(6)7/h3-8H,1-2H3;1,6-7H

HIDE SMILES / InChI

Molecular Formula C2H3Cl3O2
Molecular Weight 165.4029
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C11H12N2O
Molecular Weight 188.2262
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

CHLORAL HYDRATE ANTIPYRINE is a 1:1 mixture of antipyrine with chloral hydrate. It was used as a hypnotic drug known as HYPNAL in the late 19th century.

Approval Year

PubMed

PubMed

TitleDatePubMed
Iatrogenic encephalopathy.
1970 May
The effects of combined sedative and anxiolytic preparations on subjective aspects of sleep and objective measures of arousal and performance the morning following nocturnal medication. I: Acute doses.
1980
Patents

Patents

Substance Class Chemical
Created
by admin
on Sat Jun 26 08:11:57 UTC 2021
Edited
by admin
on Sat Jun 26 08:11:57 UTC 2021
Record UNII
7A1009H34F
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
CHLORAL HYDRATE ANTIPYRINE
Common Name English
CHLORALANTIPYRINE
Common Name English
ANTIPYRINE CHLORAL HYDRATE
Common Name English
3H-PYRAZOL-3-ONE, 1,2-DIHYDRO-1,5-DIMETHYL-2-PHENYL-, COMPD. WITH 2,2,2-TRICHLORO-1,1-ETHANEDIOL (1:1)
Systematic Name English
HYPNAL
Brand Name English
Code System Code Type Description
PUBCHEM
72941437
Created by admin on Sat Jun 26 08:11:57 UTC 2021 , Edited by admin on Sat Jun 26 08:11:57 UTC 2021
PRIMARY
CAS
603-63-4
Created by admin on Sat Jun 26 08:11:57 UTC 2021 , Edited by admin on Sat Jun 26 08:11:57 UTC 2021
PRIMARY
FDA UNII
7A1009H34F
Created by admin on Sat Jun 26 08:11:57 UTC 2021 , Edited by admin on Sat Jun 26 08:11:57 UTC 2021
PRIMARY
Related Record Type Details
PARENT -> SALT/SOLVATE
PARENT -> SALT/SOLVATE