Details
| Stereochemistry | RACEMIC |
| Molecular Formula | C17H15ClN2O.ClH |
| Molecular Weight | 335.228 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
Cl.OC1(C2=CC=CC=C2N3CCCN=C13)C4=CC(Cl)=CC=C4
InChI
InChIKey=CVTGQABRWAXYMD-UHFFFAOYSA-N
InChI=1S/C17H15ClN2O.ClH/c18-13-6-3-5-12(11-13)17(21)14-7-1-2-8-15(14)20-10-4-9-19-16(17)20;/h1-3,5-8,11,21H,4,9-10H2;1H
| Molecular Formula | C17H15ClN2O |
| Molecular Weight | 298.767 |
| Charge | 0 |
| Count |
|
| Stereochemistry | RACEMIC |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Optical Activity | ( + / - ) |
| Molecular Formula | ClH |
| Molecular Weight | 36.461 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Ciclazindol is an indole derivative and monoamine uptake inhibitor patented by pharmaceutical company John Wyeth and Brother Ltd. as an antidepressant. Besides that, Ciclazindol is effective anorectic agent, inducing weight loss in rats and man. Ciclazindol was shown to inhibit ATP-sensitive K+ (K(ATP)) channel currents and stimulate insulin secretion from CRI-G1 insulin-secreting cells. The inhibition of KATP channel currents by ciclazindol is unaffected by the removal of intracellular Mg2+ ions and after trypsinization of the cytoplasmic surface of excised patches, treatments known to abolish sulphonylurea sensitivity.
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 15:24:51 GMT 2023
by
admin
on
Fri Dec 15 15:24:51 GMT 2023
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| Record UNII |
792OU8W6Z9
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| Record Status |
Validated (UNII)
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| Record Version |
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-
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3084667
Created by
admin on Fri Dec 15 15:24:51 GMT 2023 , Edited by admin on Fri Dec 15 15:24:51 GMT 2023
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792OU8W6Z9
Created by
admin on Fri Dec 15 15:24:51 GMT 2023 , Edited by admin on Fri Dec 15 15:24:51 GMT 2023
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37647-67-9
Created by
admin on Fri Dec 15 15:24:51 GMT 2023 , Edited by admin on Fri Dec 15 15:24:51 GMT 2023
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PRIMARY |
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PARENT -> SALT/SOLVATE |
| Related Record | Type | Details | ||
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ACTIVE MOIETY |