Details
| Stereochemistry | RACEMIC |
| Molecular Formula | C17H15ClN2O.ClH |
| Molecular Weight | 335.228 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
Cl.OC1(C2=NCCCN2C3=C1C=CC=C3)C4=CC=CC(Cl)=C4
InChI
InChIKey=CVTGQABRWAXYMD-UHFFFAOYSA-N
InChI=1S/C17H15ClN2O.ClH/c18-13-6-3-5-12(11-13)17(21)14-7-1-2-8-15(14)20-10-4-9-19-16(17)20;/h1-3,5-8,11,21H,4,9-10H2;1H
| Molecular Formula | C17H15ClN2O |
| Molecular Weight | 298.767 |
| Charge | 0 |
| Count |
|
| Stereochemistry | RACEMIC |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Optical Activity | ( + / - ) |
| Molecular Formula | ClH |
| Molecular Weight | 36.461 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Ciclazindol is an indole derivative and monoamine uptake inhibitor patented by pharmaceutical company John Wyeth and Brother Ltd. as an antidepressant. Besides that, Ciclazindol is effective anorectic agent, inducing weight loss in rats and man. Ciclazindol was shown to inhibit ATP-sensitive K+ (K(ATP)) channel currents and stimulate insulin secretion from CRI-G1 insulin-secreting cells. The inhibition of KATP channel currents by ciclazindol is unaffected by the removal of intracellular Mg2+ ions and after trypsinization of the cytoplasmic surface of excised patches, treatments known to abolish sulphonylurea sensitivity.
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 17:56:54 GMT 2025
by
admin
on
Mon Mar 31 17:56:54 GMT 2025
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| Record UNII |
792OU8W6Z9
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| Record Status |
Validated (UNII)
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| Record Version |
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Systematic Name | English |
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3084667
Created by
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792OU8W6Z9
Created by
admin on Mon Mar 31 17:56:54 GMT 2025 , Edited by admin on Mon Mar 31 17:56:54 GMT 2025
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37647-67-9
Created by
admin on Mon Mar 31 17:56:54 GMT 2025 , Edited by admin on Mon Mar 31 17:56:54 GMT 2025
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PRIMARY |
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PARENT -> SALT/SOLVATE |
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ACTIVE MOIETY |