BUTAMOXANE

Details

Stereochemistry	RACEMIC
Molecular Formula	C13H19NO2
Molecular Weight	221.2955
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCCCNCC1COC2=C(O1)C=CC=C2

InChI

InChIKey=ODRQYAHPAJZPQP-UHFFFAOYSA-N

InChI=1S/C13H19NO2/c1-2-3-8-14-9-11-10-15-12-6-4-5-7-13(12)16-11/h4-7,11,14H,2-3,8-10H2,1H3

HIDE SMILES / InChI

Molecular Formula	C13H19NO2
Molecular Weight	221.2955
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/21776 | Archives Internationales de Pharmacodynamie et de Therapie (1953), 95, 285-314 | Archives Internationales de Pharmacodynamie et de Therapie (1937), 55, 15-51

Butamoxane is aminomethyl-benzodioxane derivative with sympatholytic activity. Butamoxane showes a central action as well as the adrenaline-antagonizing action.

Originator

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Adrenergic receptor alpha 64 Target ID: CHEMBL2095203 Sources: https://apps.who.int/iris/bitstream/handle/10665/275695/WHO-EMP-RHT-TSN-2018.1-eng.pdf?sequence=1&isAllowed=y	Antagonist 2778

PubMed

Title	Date	PubMed
The metabolism of drugs in isolated rat hepatocytes. A comparison with in vivo drug metabolism and drug metabolism in subcellular liver fractions.	1977 Nov-Dec	21776

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:13:26 GMT 2023` Edited by `admin` on `Fri Dec 15 16:13:26 GMT 2023`
Record UNII	7725983GSD
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

BUTAMOXANE

Official Name

English

2-(BUTYLAMINOMETHYL)-1,4-BENZODIOXANE

Systematic Name

English

butamoxane [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C72900