Details
Stereochemistry | ABSOLUTE |
Molecular Formula | C18H21NO5 |
Molecular Weight | 331.363 |
Optical Activity | UNSPECIFIED |
Defined Stereocenters | 4 / 4 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
[H][C@]12C[C@H](OC)C=C[C@]13C4=CC5=C(OCO5)C=C4CO[C@]3(O)CN2C
InChI
InChIKey=YLWAQARRNQVEHD-PBZHRCKQSA-N
InChI=1S/C18H21NO5/c1-19-9-18(20)17(4-3-12(21-2)6-16(17)19)13-7-15-14(22-10-23-15)5-11(13)8-24-18/h3-5,7,12,16,20H,6,8-10H2,1-2H3/t12-,16+,17+,18-/m1/s1
Molecular Formula | C18H21NO5 |
Molecular Weight | 331.363 |
Charge | 0 |
Count |
|
Stereochemistry | ABSOLUTE |
Additional Stereochemistry | No |
Defined Stereocenters | 4 / 4 |
E/Z Centers | 0 |
Optical Activity | UNSPECIFIED |
DescriptionSources: https://www.ncbi.nlm.nih.gov/pubmed/16557463
Sources: https://www.ncbi.nlm.nih.gov/pubmed/16557463
Lycorine, galantamine and tazettine has been found as one of the major alkaloid from Amaryllidaceae plants. Tazettine showed affinity to the serotonin reuptake transport protein.
Approval Year
Sample Use Guides
In Vitro Use Guide
Sources: https://www.ncbi.nlm.nih.gov/pubmed/14669261
Curator's Comment: Four groups of Amaryllidaceae alkaloids, one of which was tazettine was evaluated in vitro for their ability to inhibit Plasmodium falciparum growth by a high-throughput screening method with a 96-well microtiter plate. It was shown, that tazettine had the least potent activity against P. falciparum (K1).
Unknown
Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 08:09:46 GMT 2023
by
admin
on
Sat Dec 16 08:09:46 GMT 2023
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Record UNII |
76WEU12CSO
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Record Status |
Validated (UNII)
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