NIFURTHIAZOLE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C8H6N4O4S
Molecular Weight	254.223
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[O-][N+](=O)C1=CC=C(O1)C2=CSC(NNC=O)=N2

InChI

InChIKey=DUWYZHLZDVCZIO-UHFFFAOYSA-N

InChI=1S/C8H6N4O4S/c13-4-9-11-8-10-5(3-17-8)6-1-2-7(16-6)12(14)15/h1-4H,(H,9,13)(H,10,11)

HIDE SMILES / InChI

Molecular Formula	C8H6N4O4S
Molecular Weight	254.223
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://books.google.ru/books?id=xUlaDwAAQBAJ&pg=PT411&lpg=PT411&dq=NIFURTHIAZOLE retrieved from Drugs: Synonyms and Properties: Synonyms and Properties edited by George W.A Milne | https://www.ncbi.nlm.nih.gov/pubmed/29844300

Nifurthiazole, a 5-nitrofuran derivative, is an antibacterial and antiprotozoal agent, it is active against Trypanosoma. It was also used for controlling Salmonella choleraesuis in swine. The mode of action of 5-nitrofuran analogues is based on red-ox biotransformation.

Approval Year

PubMed

Title	Date	PubMed
Multidirectional Efficacy of Biologically Active Nitro Compounds Included in Medicines.	2018-05-29	29844300

Sample Use Guides

In Vivo Use Guide

LD50 (mus gvg) = 3720 mg/kg

Route of Administration: Oral

Substance Class	Chemical Created by `admin` on `Mon Mar 31 19:12:16 GMT 2025` Edited by `admin` on `Mon Mar 31 19:12:16 GMT 2025`
Record UNII	76C4HVE5L9
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

NIFURTHIAZOLE

Official Name

English

NIFURTHIAZOLE [HSDB]

Preferred Name

English

Formic acid 2-[4-(5-nitro-2-furyl)-2-thiazolyl]hydrazide

Common Name

English

HYDRAZINECARBOXALDEHYDE, 2-(4-(5-NITRO-2-FURANYL)-2-THIAZOLYL)-

Systematic Name

English

NIFURTHIAZOLE [USAN]

Common Name

English

nifurthiazole [INN]

Common Name

English

AS-17665

Code

English

NSC-525334

Code

English

Code System Code Type Description

NCI_THESAURUS

C166999